Hydrogenated castor oil polyoxyethylene ether HEL-40 (HEL-40) is a nonionic surfactant produced by ethoxylation of natural hydrogenated castor oil. According to the UN GHS classification criteria, this product does not belong to hazardous substances or mixtures and is not subject to mandatory hazard labeling. Its acute oral toxicity (rat) LD50 is greater than 5000 mg/kg, and acute dermal toxicity (rabbit) LD50 is greater than 2000 mg/kg, classifying it as practically non-toxic.
Regarding health effects, under normal use conditions, HEL-40 has no significant skin irritation, no known sensitization effects, and based on available data, no mutagenicity, carcinogenicity, or reproductive toxicity. The only note is that this product may cause mild transient eye irritation, so it is recommended to wear appropriate chemical safety goggles when handling. Prolonged or repeated contact may lead to mild skin degreasing or dryness, which is related to its basic surfactant properties rather than toxicity.
Environmentally, HEL-40 is a biodegradable nonionic surfactant that meets OECD standards and does not have significant bioaccumulation potential. At recommended usage concentrations, it is expected to be harmless to aquatic organisms and poses a low risk to the aquatic environment. However, care should be taken to prevent undiluted or untreated large quantities of the product from directly entering water bodies, soil, and public drainage systems.
| Indicator Category | Parameter | Data Source |
|---|---|---|
| Acute oral toxicity (rat) | LD50 > 5000 mg/kg | Guoli Chemical Product Database |
| Acute dermal toxicity (rabbit) | LD50 > 2000 mg/kg | Guoli Chemical Product Database |
| Skin irritation | No significant irritation | Guoli Chemical Product Database |
| Eye irritation | May cause mild transient irritation | Guoli Chemical Product Database |
| Skin sensitization | No known sensitization | Guoli Chemical Product Database |
| Mutagenicity/Carcinogenicity/Reproductive toxicity | No relevant hazard classification | Guoli Chemical Product Database |
| Biodegradability | Biodegradable (meets OECD standards) | Guoli Chemical Product Database |
| Bioaccumulation | Not significant | Guoli Chemical Product Database |
| GHS hazard classification | Not classified as hazardous substance or mixture | Guoli Chemical Product Database |
Given the mild and low-irritation properties of HEL-40, this product is particularly suitable for use in cosmetics and personal care products, such as makeup removers, skin care lotions, shampoos, and shower gels, which are directly in contact with the skin. In industrial applications such as textiles, metalworking fluids, pesticide formulations, and household hard surface cleaning, it is recommended to follow standard industrial chemical handling procedures.