Question

Is hydrogenated castor oil polyoxyethylene ether HEL-40 harmful to the human body? Does it have an impact on the environment?

Answer
2026-06-06 官方文档 氢化蓖麻油聚氧乙烯醚HEL-40

Hydrogenated castor oil polyoxyethylene ether HEL-40 is classified as practically non-toxic, has no significant skin irritation, is biodegradable, and poses a low risk to the aquatic environment. Under normal use conditions, it is relatively safe for both humans and the environment.

Detailed Explanation

Hydrogenated castor oil polyoxyethylene ether HEL-40 (HEL-40) is a nonionic surfactant produced by ethoxylation of natural hydrogenated castor oil. According to the UN GHS classification criteria, this product does not belong to hazardous substances or mixtures and is not subject to mandatory hazard labeling. Its acute oral toxicity (rat) LD50 is greater than 5000 mg/kg, and acute dermal toxicity (rabbit) LD50 is greater than 2000 mg/kg, classifying it as practically non-toxic.

Regarding health effects, under normal use conditions, HEL-40 has no significant skin irritation, no known sensitization effects, and based on available data, no mutagenicity, carcinogenicity, or reproductive toxicity. The only note is that this product may cause mild transient eye irritation, so it is recommended to wear appropriate chemical safety goggles when handling. Prolonged or repeated contact may lead to mild skin degreasing or dryness, which is related to its basic surfactant properties rather than toxicity.

Environmentally, HEL-40 is a biodegradable nonionic surfactant that meets OECD standards and does not have significant bioaccumulation potential. At recommended usage concentrations, it is expected to be harmless to aquatic organisms and poses a low risk to the aquatic environment. However, care should be taken to prevent undiluted or untreated large quantities of the product from directly entering water bodies, soil, and public drainage systems.

Technical Parameters

Indicator CategoryParameterData Source
Acute oral toxicity (rat)LD50 > 5000 mg/kgGuoli Chemical Product Database
Acute dermal toxicity (rabbit)LD50 > 2000 mg/kgGuoli Chemical Product Database
Skin irritationNo significant irritationGuoli Chemical Product Database
Eye irritationMay cause mild transient irritationGuoli Chemical Product Database
Skin sensitizationNo known sensitizationGuoli Chemical Product Database
Mutagenicity/Carcinogenicity/Reproductive toxicityNo relevant hazard classificationGuoli Chemical Product Database
BiodegradabilityBiodegradable (meets OECD standards)Guoli Chemical Product Database
BioaccumulationNot significantGuoli Chemical Product Database
GHS hazard classificationNot classified as hazardous substance or mixtureGuoli Chemical Product Database

Application Recommendations

Given the mild and low-irritation properties of HEL-40, this product is particularly suitable for use in cosmetics and personal care products, such as makeup removers, skin care lotions, shampoos, and shower gels, which are directly in contact with the skin. In industrial applications such as textiles, metalworking fluids, pesticide formulations, and household hard surface cleaning, it is recommended to follow standard industrial chemical handling procedures.

Precautions

  • It is recommended to wear chemical safety goggles and protective gloves during operation to avoid direct contact with eyes.
  • Storage temperature should be kept between 5°C and 35°C, avoiding direct sunlight and extreme temperatures.
  • Keep away from heat sources, ignition sources, and strong oxidizers; avoid storing in the same area as strong acids and strong bases.
  • Heating decomposition may release irritating fumes; ensure good ventilation in the operating area.
  • Prevent large quantities of untreated product from entering water bodies, soil, and public drainage systems.
  • If accidentally gets into eyes, immediately flush with plenty of running water for at least 15 minutes; if symptoms persist, seek medical attention promptly.
  • For specific safe handling instructions, refer to the product Safety Data Sheet (SDS).