Question

What are the main characteristics of Polyethylene Glycol PEG-600?

Answer
2026-05-17 官方文档 聚乙二醇PEG-600

Polyethylene Glycol PEG-600 is a nonionic polymer compound, with excellent emulsifying, wetting, dispersing, and solubilizing capabilities as its core advantages. It also features outstanding resistance to acids, alkalis, and hard water, and is widely used in various industries such as pharmaceuticals, daily chemicals, textiles, and metal processing.

Detailed Description

Polyethylene Glycol PEG-600 (CAS No.: 25322-68-3) is a nonionic surfactant produced by Guoli Chemical. It appears as a colorless to slightly yellow viscous liquid, which becomes a waxy solid at low temperatures. Its molecular structure is rich in ether oxygen groups, which can form hydrogen bonds with water molecules, thus imparting excellent water solubility and moisture absorption/retention properties to the product.

The core characteristics of PEG-600 are concentrated in its strong emulsifying, wetting, dispersing, and solubilizing properties. It can effectively reduce interfacial tension, allowing immiscible oil and water phases to form a stable emulsion; at the same time, it prevents particle aggregation through steric hindrance effects, playing an excellent dispersing role in systems such as ceramic slurries and coatings. Additionally, this product exhibits high tolerance to acids, alkalis, and hard water, maintaining stable performance without failure in complex industrial environments.

In terms of safety, PEG-600 is a non-hazardous substance. Its acute oral toxicity LD50 in rats is greater than 2000 mg/kg, it is non-irritating to the skin (rabbit test), and only mildly irritating to the eyes. Its overall safety is good, making it especially suitable for applications with high safety requirements such as pharmaceuticals and personal care products.

Technical Parameters

Parameter ItemParameter Detail
Product NamePolyethylene Glycol PEG-600
CAS Number25322-68-3
SynonymsPEG-600, Polyethylene Glycol 600, Polyoxyethylene 600, Macrogol 600, Polyethylene glycol 600
Product TypeNonionic polymer compound/Nonionic surfactant
AppearanceColorless to slightly yellow viscous liquid (waxy solid at low temperatures)
Core PropertiesEmulsifying, wetting, dispersing, solubilizing
ToleranceResistant to acids, alkalis, hard water
Skin IrritationNon-irritating (rabbit test)
Eye IrritationMildly irritating (rabbit test)
Acute Toxicity (LD50)>2000 mg/kg (oral, rat)
Hazard ClassificationNon-hazardous

Application Suggestions

PEG-600 has an extremely wide range of applications. Below are typical uses in various industries:

  • Pharmaceutical Field: Used as an ointment base, suppository base, pill carrier, and injection solubilizer, utilizing its water solubility and solubilizing ability to enhance drug bioavailability.
  • Personal Care Products: Used as a humectant, emulsion stabilizer, and superfatting agent for cleansing products, providing long-lasting moisturizing skin feel and improving product stability.
  • Metalworking Fluids: Used as a lubricant and coolant, forming a boundary lubrication film under high temperature and pressure, while reverse solubility provides good cooling effect.
  • Ceramics and Coatings: Used as an efficient dispersant to prevent particle aggregation, obtaining stable slurries with high solid content.
  • Rubber and Plastics: Used as an internal lubricant and mold release agent, improving processing flow and preventing adhesion to molds.
  • Textiles and Papermaking: Used as an antistatic agent, fiber softener, and leveling agent, enhancing fabric hand feel and dyeing uniformity.
  • Pesticide Formulations: Used as an emulsifying dispersant and penetration synergist, ensuring uniform dispersion of the spray solution and improving pesticide utilization.

Precautions

  • It is recommended to wear chemical safety goggles and protective gloves (e.g., nitrile rubber gloves) during operation.
  • Store in a cool, dry, well-ventilated warehouse; the temperature is recommended not to exceed 40°C; keep the container tightly closed to prevent moisture absorption.
  • Keep away from strong oxidizing agents (e.g., peroxides, hypochlorites, permanganates) and strong acids, strong alkalis; store separately.
  • In case of eye contact, rinse immediately with plenty of water, lifting upper and lower eyelids, for at least 15 minutes; if irritation persists, seek medical attention immediately.
  • This product is flammable; in case of fire, water mist, alcohol-resistant foam, dry chemical powder, or carbon dioxide (CO2) extinguishers are suitable.