Question

How to use PEG600MO (Polyethylene Glycol 600 Monooleate)? What is the recommended dosage?

Answer
2026-06-06 官方文档 PEG600MO,聚乙二醇600单油酸酯

PEG600MO (Polyethylene Glycol 600 Monooleate) is a nonionic O/W emulsifier with an HLB value of approximately 13.5, featuring prominent hydrophilicity. Its usage method and dosage should be determined based on the specific application field and target system. The Guoli Chemical product database does not provide specific dosage data for each application field. The following guidance is based on product characteristics and general industry experience.

Usage Instructions

PEG600MO appears as a light yellow to yellow liquid or paste at room temperature (25°C), with a freezing point of approximately 5~10°C. If the product solidifies or pastes due to low-temperature storage, place the container in a warm environment (recommended 25~35°C) for slow reheating, or use an indirect water bath with moderate stirring to restore fluidity. Do not heat directly with open flames or steam.

As an O/W emulsifier, PEG600MO can be added in two general ways: (1) Oil-Phase Addition Method — Mix the product with oil-phase components such as oils and waxes, heat to 60~75°C with stirring, then emulsify with a preheated aqueous phase (usually at the same temperature); (2) Aqueous-Phase Addition Method — Due to its good water solubility, it can be directly added to the aqueous phase, heated to dissolve, and then mixed with the oil phase for emulsification. For solubilization applications (e.g., fragrance or essential oil solubilization), premix PEG600MO with the solubilizate uniformly, then slowly add water under stirring until a transparent or translucent microemulsion forms.

This product is a low-foaming nonionic surfactant with excellent compatibility with anionic, cationic, and amphoteric surfactants. For compounding, calculate based on the target HLB value. The HLB value of PEG600MO is 13.5 (database measured value), effectively enhancing the overall hydrophilicity of the formulation. Note that the product is not resistant to strong alkaline environments and should be avoided in systems with pH>10 for long-term use.

Recommended Dosages for Various Application Fields (General Industry Reference)

Application Field Recommended Dosage (wt%) Functional Role
Cosmetic Creams/Lotions 1.0~5.0 Primary O/W emulsifier or co-emulsifier
Makeup Remover/Cleansing Products 3.0~10.0 Emulsifying solubilizer, helps oil-phase emulsify upon contact with water
Fragrance/Essential Oil Solubilization 1:1~3:1 (solubilizate basis) Solubilizer, forms transparent aqueous solutions
Textile Softening/Anti-static Treatment 2.0~8.0 (treatment bath concentration) Softening agent, antistatic agent
Metalworking Fluids 5.0~15.0 (in concentrate) Emulsifier and auxiliary lubricant component
Pesticide Emulsifiable Concentrates/Emulsions in Water 3.0~10.0 Nonionic pesticide emulsifier
Industrial Cleaners 1.0~5.0 Oil emulsifier, dispersant
Drug Solubilization 0.5~5.0 Solubilizer for poorly soluble drugs

Note: The above dosages are general industry empirical values. The optimal dosage for a specific application should be determined through orthogonal experiments based on the actual formulation system, oil phase type and content, and target product performance. The Guoli Chemical database does not include specific recommended dosages for each application field. It is recommended that users start with the lower end of the suggested range and optimize gradually.

Handling and Usage Precautions

  • Heating Temperature Control: Conventional emulsification temperature is recommended at 60~75°C, preferably not exceeding 80°C, to avoid decomposition of ester bonds under prolonged high-temperature exposure.
  • Homogenization Method: Use high-shear or high-pressure homogenization equipment for emulsification to achieve finer and more stable droplet size distribution.
  • pH Range: The product is stable within pH 4.5~7.5 (1% aqueous solution pH 5.0~7.0), not resistant to strong alkali, and not suitable for alkaline formulations with pH>10.
  • Storage Conditions: Keep sealed in a cool, dry place at 5~30°C. The product is hygroscopic; use promptly after opening and avoid prolonged exposure to humid air.
  • Safety Precautions: Wear protective gloves and goggles during handling, and use in a well-ventilated area. The product may cause skin and eye irritation (GHS Category 2). In case of accidental contact, rinse immediately with plenty of water for at least 15 minutes and seek medical attention if necessary.