Polyether L-62 (Poloxamer 182) is a non-ionic polyoxyethylene polyoxypropylene block copolymer produced by Hainan County Guoli Chemical Co., Ltd. According to GHS classification, this product falls under skin irritation (Category 2), serious eye damage/eye irritation (Category 2A), specific target organ toxicity - single exposure (Category 3, respiratory irritation), and chronic aquatic toxicity (Category 3), requiring corresponding engineering controls and personal protective measures throughout the entire use process.
The product has low acute oral toxicity (LD₅₀ (rat) > 2000 mg/kg), with no mutagenicity, carcinogenicity, or reproductive toxicity observed. However, with a flash point above 150°C (closed cup), it can still burn when exposed to open flames and high heat, so storage and use must be kept away from ignition sources and heat. Combustion may produce harmful gases such as carbon monoxide and carbon dioxide.
In terms of ecological safety, Polyether L-62 is harmful to aquatic life with long-lasting effects (H412). Therefore, untreated wastewater must not be directly discharged into natural water bodies, and waste disposal must comply with local environmental regulations.
| Hazard Category | GHS Classification | Hazard Code |
|---|---|---|
| Skin Irritation | Category 2 | H315 |
| Serious Eye Damage/Eye Irritation | Category 2A | H319 |
| Specific Target Organ Toxicity (Single Exposure, Respiratory Irritation) | Category 3 | H335 |
| Chronic Aquatic Toxicity | Category 3 | H412 |
| Parameter | Value |
|---|---|
| Acute Oral Toxicity LD₅₀ (Rat) | > 2000 mg/kg |
| Mutagenicity | Not observed |
| Carcinogenicity | Not observed |
| Reproductive Toxicity | Not observed |
| Flash Point (Closed Cup) | > 150°C |
| Explosivity | None |
| Hazardous Combustion Products | Carbon monoxide, carbon dioxide |
Engineering Controls and Ventilation: The work area should be equipped with local exhaust ventilation or general ventilation systems. Use only outdoors or in a well-ventilated area (P271). Avoid large-scale operations in enclosed spaces. If mist/vapor/spray is generated, enhance ventilation.
Personal Protective Equipment (PPE):
Work Habits: Avoid inhaling mist/vapor/spray during operation (P261). Thoroughly wash hands and exposed skin after operation (P264). Do not eat, drink, or smoke in the work area.
| Exposure Route | First Aid Method |
|---|---|
| Skin Contact | Remove contaminated clothing and rinse thoroughly with plenty of running water. If irritation persists, seek medical attention (P302+P352, P332+P313) |
| Eye Contact | Immediately lift eyelids and rinse carefully with running water or saline solution for several minutes. If wearing contact lenses, remove them and continue rinsing. If eye irritation persists, seek medical attention (P305+P351+P338, P337+P313) |
| Inhalation | Quickly move the person to fresh air, maintain a clear airway, and keep in a comfortable breathing position. If breathing is difficult, give oxygen; if breathing stops, immediately perform artificial respiration and seek medical attention (P304+P340) |
| Ingestion | Drink plenty of warm water, induce vomiting, and seek medical attention immediately (P312) |
Storage Conditions:
Firefighting Measures: Firefighters must wear self-contained breathing apparatus and full fireproof and chemical protective clothing, and fight fire from upwind. If possible, move containers from the fire area to an open space, spray water to cool containers until fire is out. Suitable extinguishing agents include water spray, foam, dry powder, carbon dioxide, and sand.
Spill Emergency Response:
Polyether L-62 is harmful to aquatic life with long-lasting effects. Wastewater after use must be treated to meet standards before discharge and must not be directly discharged into natural water bodies. Waste products and packaging should be handled by qualified units in accordance with local hazardous waste management regulations.
The above safety information is compiled based on the product data of Polyether L-62 provided by Hainan County Guoli Chemical Co., Ltd. Please refer to the Safety Data Sheet (SDS) before use.