Polypropylene glycol PPG-200 is a low-toxicity chemical product and is not classified as a hazardous material under normal conditions. However, during handling, eye protection, ventilation, and adherence to storage and emergency procedures are still required.
Detailed explanation
Polypropylene glycol PPG-200 (CAS No.: 25322-69-4) has low acute toxicity. The oral LD50 in rats is > 2000 mg/kg, and it is not classified as a hazardous material during normal transport and storage. However, according to GHS classification criteria, this product may cause eye irritation (H319), which is the most concerning risk during use. Long-term or repeated skin contact may also lead to skin defatting and dryness, so protective measures must not be overlooked during routine operations.
In terms of operational protection, it is recommended that workers wear chemical safety goggles and chemically resistant gloves to avoid direct contact with eyes and skin. The work area should be well-ventilated, and local exhaust ventilation should be used if necessary. After operation, hands and any potentially exposed skin must be thoroughly washed with water and soap. Eating, drinking, and smoking are prohibited in the workplace. Operators should receive systematic training on chemical safety operating procedures.
For storage, this product should be kept in a cool (recommended temperature 5–35°C), dry, well-ventilated warehouse, away from ignition sources, heat sources, and strong oxidizers. Containers must be kept sealed to prevent moisture absorption, and stored separately from food, feed, strong acids, and strong alkalis. The recommended storage period is no more than 24 months from the production date. After this period, re-inspection is required before further use.
Safety technical parameters
| Parameter | Value |
|---|
| Toxicity classification | Low toxicity, non-hazardous |
| Acute toxicity (LD50, oral, rat) | > 2000 mg/kg |
| Flash point (closed cup) | > 150 °C |
| GHS classification | May cause eye irritation (H319) |
| Recommended storage temperature | 5–35 °C |
| Recommended storage period | 24 months from production date |
Application safety recommendations
PPG-200 is widely used in synthetic lubricants, hydraulic fluids, mold release agents, defoamers, cosmetic intermediates, polyurethane flexible foam, and other fields. In each application scenario, risk assessment is recommended based on specific process conditions:
- High temperature conditions: Although the flash point is >150°C, in high-temperature applications (e.g., high-temperature chain oil, compressor oil blending), the temperature should be kept well below the flash point and equipment should be sealed.
- Open operations: During open operations such as mold release agent spraying or defoamer addition, local ventilation should be strengthened to avoid prolonged inhalation of vapor or mist.
- Cosmetic use: Final products must comply with relevant cosmetic safety regulations to ensure residual monomers and impurities are within safe limits.
- Leak prevention: During pumping or repackaging, spill containment trays are recommended to prevent accidental leakage into drains or water bodies.
Emergency response precautions
- Skin contact: Immediately remove contaminated clothing and thoroughly flush skin with plenty of water and soap; if irritation occurs, seek medical attention promptly.
- Eye contact: Immediately flush with plenty of water or saline for at least 15 minutes, lifting eyelids to ensure thorough cleaning; if irritation persists, seek medical attention immediately.
- Inhalation discomfort: Move the person to fresh air and keep breathing unobstructed; if unwell, seek medical attention.
- Ingestion: Rinse mouth with water, do NOT induce vomiting, seek medical attention immediately and show product label or safety instructions.
- Fire fighting: Use water spray, alcohol-resistant foam, dry powder, or carbon dioxide; firefighters must wear self-contained positive pressure breathing apparatus and full protective clothing. Combustion may produce carbon monoxide, carbon dioxide, and incompletely burned hydrocarbons.
- Spill handling: Small spills: absorb with inert absorbent material (e.g., sand, vermiculite) and collect in a sealed container; large spills: contain the source to prevent entry into drains or water bodies. Waste disposal must be carried out by a licensed waste treatment agency. Do not discharge into drains, surface water, or groundwater.
Note: The above information is based on the product database and accompanying Safety Data Sheet of Haian Guoli Chemical Co., Ltd. For more toxicological details, please refer to the complete SDS.
