Polyoxyethylene Stearate SG-6 (PEG-6 Stearate) is a nonionic surfactant produced by Guoli Chemical. Comprehensive toxicological evaluations indicate that its risk to human health is extremely low. This product has passed multiple standardized toxicological tests and does not pose significant harm to humans under normal industrial and cosmetic use conditions. It is a green chemical product that aligns with current environmental protection and sustainable development trends in the industry.
In terms of human safety, SG-6 exhibits excellent skin compatibility—a 4-hour closed patch test on rabbits showed a Primary Irritation Index (PII) of less than 0.5, classifying it as non-irritating; a guinea pig skin sensitization test yielded a sensitization rate of 0%, confirming no sensitizing potential. The only point of caution is ocular contact: rabbit tests indicated possible mild reversible irritation (e.g., conjunctival redness, edema), but recovery occurs within a few days without permanent damage. The acute oral toxicity LD50 is greater than 2000 mg/kg (rats), classifying it as low toxicity.
Regarding environmental impact, SG-6 exhibits outstanding eco-friendly characteristics. Aquatic toxicity tests show: fish 96h LC50, Daphnia 48h EC50, and algae 72h ErC50 are all greater than 100 mg/L, indicating low aquatic toxicity. More importantly, according to OECD 301B standards, the product achieves over 60% biodegradation within 28 days, making it readily biodegradable. Once released into the environment, it can be naturally decomposed by microorganisms, has no bioaccumulation potential, and has very low impact on aquatic ecosystems.
| Safety Indicator | Test Result | Conclusion |
|---|---|---|
| Acute Oral Toxicity (Rat) | LD50 > 2000 mg/kg | Low Toxicity |
| Skin Irritation (Rabbit, 4h closed) | PII < 0.5 | Non-irritating |
| Eye Irritation (Rabbit) | Mild redness, edema | Mild reversible irritation, recovery in days |
| Skin Sensitization (Guinea Pig) | Sensitization rate 0% | No sensitizing potential |
| Fish Acute Toxicity (96h LC50) | > 100 mg/L | Low aquatic toxicity |
| Biodegradability (OECD 301B, 28 days) | > 60% | Readily biodegradable |
| Bioaccumulation | — | No bioaccumulation potential |
| Flash Point (Closed Cup) | > 150°C | Non-flammable |
Given the favorable safety profile of SG-6, it is widely used in areas involving direct or indirect human contact: