Question

Precautions for using Span S-80?

Answer
2026-05-17 官方文档 司盘S-80

When using Span S-80, special attention must be paid to skin and eye protection, workspace ventilation, storage conditions, and emergency treatment in four major aspects. This product is a nonionic surfactant with stable chemical properties, but direct contact may cause irritation reactions.

Detailed Description

Span S-80 (Sorbitan Monooleate) is an amber to brown viscous liquid with a flash point above 149°C (closed cup). Under normal operating conditions, it is not classified as a flammable hazard, but it should still be kept away from high temperatures and open flames. Its main hazard lies in health effects: According to GHS classification, this product is classified as Skin Irritation Category 2 (H315: Causes skin irritation), Serious Eye Damage\/Eye Irritation Category 2 (H319: Causes serious eye irritation), and Specific Target Organ Toxicity Single Exposure Category 3 (H335: May cause respiratory irritation). Therefore, personal protective equipment must be worn throughout the entire operation, and caution should never be taken lightly.

In daily use, Span S-80 exhibits good chemical stability, maintaining stable surface activity under acidic, alkaline, and hard water conditions, and is compatible with most substances except strong oxidizers. However, it should be noted that despite its high flash point, prolonged exposure to high temperatures may lead to product deterioration. The storage temperature is recommended to be controlled below 40°C. Opened containers should be promptly resealed and stored upright to prevent leakage and moisture absorption.

In formulation applications, Span S-80, as a W\/O emulsifier, is typically dissolved by heating in the oil phase before participating in the emulsification process. Operations should be carried out in a well-ventilated area to avoid prolonged inhalation of vapors or mists generated during heating. The stability of the emulsion system is closely related to the dosage of Span S-80, the oil-to-water ratio, and the homogenization conditions. It is recommended to determine the optimal dosage and process parameters through small-scale trials.

Technical Parameters

Parameter ItemSpecification
Product NameSpan S-80 (Sorbitan Monooleate)
CAS Number1338-43-8
AppearanceAmber to brown viscous liquid
Ionic TypeNonionic Surfactant
Emulsion TypeW\/O (Water-in-Oil)
Flash Point>149°C (Closed Cup)
GHS Skin Irritation ClassificationCategory 2 (H315: Causes skin irritation)
GHS Eye Damage ClassificationCategory 2 (H319: Causes serious eye irritation)
GHS Inhalation Toxicity ClassificationCategory 3 (H335: May cause respiratory irritation)
Recommended Storage Temperature<40°C

Application Suggestions

Span S-80 is widely used in cosmetic creams and lotions, food emulsification systems, pharmaceutical ointment bases, pesticide emulsifiable concentrates, petroleum-based lubricants, textile fiber oils, and plastic processing. In practical use, it is recommended to:

  • When used as the primary W\/O emulsifier, typically heat it together with the oil phase to 50-70°C for complete dissolution, then slowly add the water phase for homogenization emulsification.
  • Can be compounded with Tween series (such as Tween 80) to adjust the HLB value to achieve O\/W or a wider range of emulsification effects.
  • For food-grade applications, ensure the selection of specifications compliant with food additive standards (E494).
  • In pesticide formulations, the recommended dosage is typically 3%-8% of the total formulation, but specific amounts should be determined experimentally based on the properties of the technical material and the solvent system.

Precautions

  • Personal Protective Equipment: Wear protective gloves, protective clothing, and eye protection\/face shield during operation. After work, thoroughly wash hands and any exposed skin.
  • Ventilation Requirements: Ensure the work area is well-ventilated; avoid inhaling vapors or mists. It is recommended to use explosion-proof ventilation and lighting equipment.
  • Eye Contact Emergency: If eye contact occurs, immediately flush with plenty of water for several minutes, remove contact lenses if present and continue flushing. If irritation persists, seek medical attention.
  • Skin Contact Emergency: Immediately wash with plenty of soap and water. If skin irritation persists, seek medical attention.
  • Inhalation Emergency: Move the person to fresh air, keep breathing comfortable, and seek medical attention if discomfort persists.
  • Ingestion Emergency: Do NOT induce vomiting. Immediately rinse mouth and call a poison center or seek medical attention.
  • Spill Handling: Contain spills with inert absorbent material (such as sand), collect in a sealed container for disposal, and do not discharge into drains.
  • Storage Requirements: Store in a cool, dry, well-ventilated area, keep containers tightly closed, away from strong oxidizers, and maintain storage temperature below 40°C.
  • Disposal: Dispose of as hazardous waste in accordance with local regulations; do not mix with household waste.