Question 1

Is Span S-80 harmful to humans? Does it have an impact on the environment?

Accepted Answer

Under normal use conditions, Span S-80 is a low-toxicity product to humans, but it can cause skin, eye, and respiratory irritation. It has some harm to the aquatic environment but can be gradually biodegraded in the natural environment. Detailed explanation Span S-80 (Sorbitan monooleate) is a classic nonionic surctant widely used in food, cosmetics, pharmaceuticals, and other fields. According to product safety data, this product itself is not a highly toxic or highly poisonous substance, and its acute toxicity is low. However, upon direct contact or improper operation, it may cause local irritation to the human body, mainly manifesting as skin irritation, eye irritation, and respiratory irritation. It should be particularly noted that Span S-80 has been approved for use as a food additive (International Number E494), and its usage in food is strictly limited. Within this limit, it is safe for human consumption. However, when used as an industrial-grade raw material for direct contact (e.g., by operators during production), appropriate protective measures must still be taken because the industrial product has a high concentration and significant irritation. Potential health effects on humans Route of exposureHazard categorySpecific manifestations Skin contactCategory 2 — H315Causes skin irritation, manifesting as redness, swelling, itching, or dry desquamation Eye contactCategory 2 — H319Causes serious eye irritation, manifesting as pain, tearing, conjunctival congestion InhalationCategory 3 — H335Vapors or droplets may cause respiratory irritation, leading to coughing or respiratory discomfort IngestionLow acute toxicityMay cause gastrointestinal discomfort; medical attention is required for large intake Carcinogenicity/MutagenicityNot classifiedCurrently, no evidence suggests it has carcinogenic, mutagenic, or reproductive toxicity Potential environmental impact Span S-80 is an organic ester compound that has certain biodegradability in the natural environment and will not persist and accumulate in the environment. However, as a surctant, it has strong intercial activity. If discharged into water bodies in large quantities, it may adversely affect aquatic organisms (such as fish, algae, and plankton), mainly by destroying the protective mucus layer on the surce of organisms or affecting cell membrane permeability. Under normal use and compliant discharge conditions, the environmental risk of Span S-80 is controllable. However, environmental regulations must be strictly followed, and it is strictly forbidden to discharge untreated products or wastewater containing its components directly into sewers, surce water, or groundwater bodies. In case of leakage, inert absorbent materials (such as sand) should be used for collection and disposal in accordance with hazardous waste regulations. Safe use recommendations Personal protective measures Must wear protective gloves, protective clothing, and protective goggles/ce shields during operation Ensure the workplace is well ventilated to avoid inhaling vapors or droplets Thoroughly wash hands and any skin areas that may have been in contact after operation Keep away from high temperatures and open flames (flash point >149°C, but still be cautious) Emergency treatment points Skin contact: Immediately rinse with plenty of soap and water; if irritation persists, seek medical attention Eye contact: Carefully rinse with water for several minutes, remove contact lenses if present and continue rinsing; if symptoms persist, seek medical attention Inhalation discomfort: Move to fresh air and keep breathing unobstructed; if discomfort persists, seek medical attention Ingestion: Do not induce vomiting, immediately rinse mouth and seek medical attention Environmental precautions Waste liquid containing the product should be collected and treated, and must not be discharged directly into the environment Dispose of waste product and contaminated packaging in accordance with local hazardous waste regulations In case of large spills, contain the spill source to prevent entry into drainage systems and natural water bodies Store product in a cool, dry, well-ventilated place (recommended

Question 2

What should I do if problems occur during the use of Span S-80? How to get technical support?

Accepted Answer

Don't panic when encountering problems with Span S-80. First, check the key process parameters according to the problem type, and then contact the Guoli Chemical technical team for in-depth support. Common Usage Problems and Troubleshooting Methods Span S-80 (CAS: 1338-43-8) is a lipophilic non-ionic surctant with an HLB value of about 4.3. Common problems during use are usually related to emulsion system design, operating temperature, addition amount, and phase ratio. The following are common abnormalities and troubleshooting directions: 1. Unstable emulsion, layering or demulsification: First check whether the ratio of oil phase to water phase is reasonable. As a W/O emulsifier, Span S-80 usually requires the oil phase to be the continuous phase (recommended oil phase ratio >50%). Secondly, confirm whether the addition amount is sufficient, generally recommended dosage is 1%~5% of the total formula. In addition, Span S-80 is often used in combination with low-HLB emulsifiers (such as Tween series); using it alone may have limited emulsification effect. 2. Difficulty in dissolving or uneven dispersion of the product: Span S-80 is difficult to dissolve in water and should be pre-dissolved and dispersed in the oil phase. It is recommended to add Span S-80 to the oil phase, heat to 40~50°C with stirring to dissolve, and then mix with the water phase for homogenization. If the operating temperature is too low, the product viscosity is high (kinematic viscosity at 25°C is about 1000~2000 mm²/s), making uniform dispersion difficult. 3. Abnormal product appearance (color, odor, layering): The normal state of Span S-80 is an amber to brown viscous liquid. If there is severe color darkening, off-odor, or obvious layering, it may be related to improper storage - recommended storage temperature below 40°C, container tightly sealed, away from strong oxidizers. Do not continue to use deteriorated products; contact the supplier for confirmation. 4. Skin or eye irritation: This product is a skin/eye irritant (H315/H319). ilure to wear protective gloves and goggles during operation may cause discomfort. Emergency measures: In case of skin contact, wash immediately with soap and water; in case of eye contact, rinse with water for several minutes and seek medical attention. How to Get Official Technical Support from Guoli Chemical If the problem is still not resolved after completing the above troubleshooting, it is recommended to obtain professional technical assistance through the following channels: Consult product documentation: On the product detail page of the Guoli Chemical official website, you can obtain the complete Technical Data Sheet (TDS) and Safety Data Sheet (SDS), which contain detailed information on technical parameters, compatibility guidelines, and safe operation requirements. Contact the sales manager: Seek technical consultation through the sales representative or distributor you worked with; the sales manager can usually coordinate a technical engineer to answer your questions directly. Send an email or call for consultation: Contact the customer service center of Hai'an County Guoli Chemical Co., Ltd. directly, providing the product batch number, a specific description of the problem (photos or samples are recommended), and the company's technical department will provide targeted solutions. Tips Since the direct customer service phone number and email address of Guoli Chemical are not yet included in the product database, it is recommended that you obtain the latest technical support channels through the "Contact Us" section of the company's official website or the contact information on the product packaging. When communicating, preparing the following information in advance can speed up problem resolution: product name and batch number, usage formula and application conditions, and a detailed description of the abnormal phenomenon (can be accompanied by photos or sample comparisons).

Question 3

How to purchase Span S-80? What is the minimum order quantity?

Accepted Answer

To purchase Span S-80, please contact the Guoli Chemical sales team directly. There is no publicly disclosed minimum order quantity limit, and the price is determined based on real-time quotations. Detailed Description Span S-80 (Sorbitan monooleate, CAS: 1338-43-8) is a classic nonionic surctant product of Guoli Chemical. Currently, this product has no fixed online retail price in the database. The actual transaction price needs to be confirmed with the sales team, and the final price is dynamically adjusted based on ctors such as order quantity, payment method, and current raw material market conditions. Regarding the minimum order quantity, the standard packaging specifications are 50kg or 200kg plastic drums, but the database does not specify a mandatory minimum order quantity. Whether for small batch samples or ton-level procurement, it is recommended to directly contact the Guoli Chemical business staff for customized quotation and delivery time. Purchase Information ItemDetails Standard packaging50kg / 200kg plastic drums Minimum order quantityNo clear limit, please contact sales for confirmation Price acquisition methodContact Guoli Chemical sales team for the latest quotation Price noteThe above prices are for reference only, actual price shall prevail upon contract signing Purchase Process Suggestions You can contact the Guoli Chemical sales team through the official website contact information or by calling the sales hotline. Explain the required product name (Span S-80), specification requirements, and estimated quantity to the business staff. It is recommended to prepare relevant qualification information such as the company business license in advance to quickly establish a customer profile and arrange sample delivery or order processing. Notes This product is a non-hazardous chemical, but transportation and storage must comply with chemical management regulations, ensuring intact packaging and storage in a cool and ventilated place. Free samples can be requested before bulk procurement for formulation compatibility testing.

Question 4

Does Span S-80 meet environmental requirements? Can the test report be provided?

Accepted Answer

Span S-80 itself does not have an independent environmental certification mark, but its environmental compliance can be evaluated from multiple dimensions; for the test report, please contact the Guoli Chemical business team. Detailed Explanation Span S-80 (sorbitan monooleate, CAS number: 1338-43-8) is a classic nonionic surctant, and its environmental compliance needs to be comprehensively evaluated from multiple perspectives. First of all, this product is allowed to be used as an emulsifier in the food industry (corresponding to food additive number E494), indicating that it has undergone safety assessment in food contact scenarios and has high biocompatibility. Secondly, the product is synthesized from natural sources of sorbitol and oleic acid, and the ester bonds in the molecular structure can undergo hydrolysis in the natural environment, showing certain biodegradation potential. In terms of regulatory compliance, this product is widely used in strictly regulated industries such as cosmetics, pharmaceuticals, and food, indirectly indicating that it meets the safety requirements of related industries. However, according to safety instructions, the product is classified as skin irritation (Category 2) and eye irritation (Category 2), and it is explicitly required in leakage disposal "not to be discharged into waterways," and must be treated as hazardous waste in accordance with local regulations. Therefore, it cannot be simply defined as a "green" product; it may have a certain impact on aquatic ecology, and its use and discharge must be strictly controlled. Regarding the Test Report The Guoli Chemical database currently does not embed specific batch test report files. Formal test reports usually include product technical indicators (such as acid value, saponification value, hydroxyl value, water content, etc.), batch measured data, and quality inspection conclusions, which are documents issued with each batch. To obtain the following types of test reports, it is recommended to directly contact the sales or technical department of Guoli Chemical: Product Certificate of Analysis (COA) Quality test report from third-party testing institutions Environmental compliance declarations such as ROHS, REACH, etc. Test report for limits of heavy metals and harmful substances Special test report for food grade or pharmaceutical grade Key Points for Environmental Compliance Assessment Assessment DimensionSituation of Span S-80 Food additive permitNumber E494, allowed in food emulsification systems BiodegradabilityEster bond structure can be hydrolyzed, showing certain degradation potential (no specific degradation rate data currently) Aquatic toxicityNo data available, but safety instructions require not to be discharged into waterways Volatile organic compoundsFlash point >149°C, low volatility Heavy metals/harmful impuritiesNo data available, need to request special test report from manucturer REACH complianceIf used in the EU market, can request compliance declaration from manucturer Hazardous waste managementWaste disposal must be treated as hazardous waste according to local regulations, not mixed with household waste Application Recommendations In environmentally sensitive applications (such as cosmetics exported to the EU, food packaging related products), it is recommended to: First, clarify the regulatory requirements of the end market (such as REACH, FDA, China GB standards); Second, request from Guoli Chemical the corresponding batch COA and third-party environmental test report; Third, if the product requires environmental certification (such as ECO-cert, COSMOS organic or natural certification), evaluate whether Span S-80 is on the list of allowed raw materials, as it is a semi-synthetic surctant and not a natural source raw material. Precautions Although this product is widely used in food and medicine, its safety instructions clearly indicate the risk of skin and eye irritation, and production waste liquid must not be directly discharged. In environmental compliance reviews, enterprises should comprehensively consider the environmental impact throughout the product life cycle. It is recommended to consult Guoli Chemical for the latest environmental compliance status and the list of available test reports.

Question 5

What are the advantages of Span S-80 compared to similar products?

Accepted Answer

The core advantage of Span S-80 lies in its outstanding lipophilicity as a classic water-in-oil (W/O) emulsifier, broad formulation compatibility, and extremely diverse cross-industry applications, making it a benchmark choice in oil-based/hydrophobic formulation systems. Detailed Explanation In the Span series products of Hai'an Guoli Chemical, the fundamental differentiation of Span S-80 (Sorbitan Monooleate) from similar products lies in its unique tty acid chain structure. S-80 is grafted with monounsaturated oleic acid. Compared to Span S-60 (stearic acid, saturated) or Span S-20 (lauric acid, short chain), the oleic acid chain endows S-80 with a lower pour point (melting point only 10~12°C) and a liquid state at room temperature, allowing direct dispersion without melting during processing, offering significantly greater operational convenience than the waxy solid S-40 and S-60. More importantly, its HLB value is approximately 4.3, which is in the very low hydrophilic-lipophilic balance range of nonionic surctants, determining its high efficiency in forming water-in-oil emulsions, requiring only low addition levels to create a stable intercial film. Beyond internal comparison within the Span series, when compared with the Tween series (e.g., Tween T-80, which is also oleate but with polyoxyethylene chains), the advantages are distinctly different: Tween T-80 is an oil-in-water emulsifier, while Span S-80 is a water-in-oil emulsifier. They are often used in combination, but for building an oil-based skeleton and achieving dispersion and emulsification in pure oil systems or high oil phase formulations, Span S-80 is an irreplaceable core. Additionally, compared to ionic emulsifiers, the nonionic nature of Span S-80 ensures chemical stability in hard water, acidic, and alkaline media, remaining active unaffected by metal ions in water, offering strong adaptability to working conditions. In terms of application breadth, Span S-80 truly achieves "one specialty with multiple capabilities." It is not only the preferred W/O emulsifier for cosmetic creams, pesticide emulsifiable concentrates, and lubricating oils but also integrates multiple functions such as dispersion, wetting, lubrication, and antistatic properties. For example, it serves as an internal lubricant and antistatic agent in plastic processing, and as a smoothing agent in textile fibers. This ability to achieve multiple effects with a single component is difficult for many single-structure similar emulsifiers to match. Moreover, it complies with food additive standard E494 and can be used in food systems, a qualification many industrial-grade surctants lack. Technical Parameter Comparison (Guoli Chemical Product Database) Parameter Span S-80 (Oleate) Span S-60 (Stearate) Tween T-80 (Oleate Ether) Form and Physical State Yellow to amber viscous liquid (room temperature) White to light yellow waxy solid Light yellow to amber viscous liquid Melting Point 10~12°C Higher (melts upon heating) Liquid (may thicken at low temperatures) HLB Value 4.3 (W/O emulsifier) This parameter is not available (W/O emulsifier) This parameter is not available (O/W emulsifier) Saponification Value 145~160 This parameter is not available This parameter is not available Hydroxyl Value 200~240 This parameter is not available This parameter is not available Iodine Value 65~85 (contains unsaturated double bonds) This parameter is not available (saturated) This parameter is not available Dynamic Viscosity (25°C) 1000~2000 mm²/s This parameter is not available This parameter is not available Chemical Stability Resistant to hard water, acid, and alkali; ester bond may hydrolyze in alkaline conditions Similar Similar Food Applicability Yes (E494) Yes (E491) This parameter is not available Application Recommendations 1. When you need to build a pure oil-based or high internal phase water-in-oil system (e.g., rust preventive oil, ointment base, baking release oil), first choose Span S-80: Its liquid form allows direct dispersion, and the high lipophilicity from the HLB value of 4.3 enables spontaneous formation of reverse micelles in oil, stabilizing fine water droplets or solid particles. 2. When pursuing processing convenience and anti-congealing in winter (e.g., textile oils, low-temperature lubricants), first choose Span S-80: Compared to room-temperature solid products like S-60, S-80 maintains fluidity at low temperatures, reducing preheating steps and suitable for continuous pipeline transport. 3. When compounding emulsifiers to produce ultrafine emulsions: Span S-80 is often mixed with high HLB O/W emulsifiers like Tween T-80 in a certain ratio, leveraging the affinity of the oleic acid chain to obtain a more compact intercial film than with a single emulsifier. We recommend testing the optimal ratio using the HLB value additive formula. 4. When needing both internal and external lubrication/antistatic properties in plastic or fiber processing: Span S-80 serves multiple functions with a single agent, simplifying formulation and reducing compatibility issues of multiple additives. Precautions Risk of ester bond hydrolysis: Like all sorbitan tty acid esters, the ester bond of Span S-80 can be hydrolyzed under strong alkaline conditions and high temperatures. If the formulation system is strongly alkaline and requires long-term storage, please evaluate stability or adopt cold processing techniques. Iodine value reflects unsaturation: S-80 contains oleic acid unsaturated double bonds (iodine value 65~85). Prolonged exposure to air may lead to slow oxidation and darkening. We recommend storing in a sealed container, protected from light at temperatures below 40°C. Calculate HLB for compounding: S-80 has a very low HLB when used alone. To temporarily prepare an O/W emulsion, it must be compounded with a high HLB emulsifier; it cannot be used alone. Safe operation: Wear protective gloves and goggles during operation, and ensure ventilation. Although the flash point is >149°C, remain cautious under high temperature and open flame conditions.

Question 6

How should Span S-80 be stored? What is its shelf life?

Accepted Answer

Span S-80 is recommended to be stored in a cool, dry, well-ventilated place, sealed, with temperature below 40°C. Under unopened conditions, the general shelf life is 24 months. Detailed Explanation Span S-80 (Sorbitan monooleate) is a chemically stable nonionic surctant that is not prone to hydrolysis or oxidative degradation under normal storage conditions. To ensure the product quality remains optimal, controlling the storage environment is crucial. The product should be stored in a dedicated chemical storage area that is cool, dry, and well-ventilated. The container must be kept tightly sealed to prevent moisture and impurities from entering. Regarding the shelf life, according to general standards for nonionic surctants in the chemical industry, Span S-80, under original unopened packaging and compliant storage conditions, typically has a shelf life of 24 months (2 years). However, the specific shelf life of the product should be based on the expiration date indicated on the product packaging or the Certificate of Analysis (COA). Each batch of products from Guoli Chemical is accompanied by a corresponding quality inspection report. It should be noted that even if the product is within its shelf life, improper storage (such as prolonged exposure to high temperature, high humidity, or loose sealing) may lead to color deepening, viscosity changes, or decreased emulsifying performance. Therefore, it is recommended to follow the "first-in, first-out" principle and use the product as soon as possible within the shelf life. Key Storage Conditions Storage ctorSpecific Requirement Storage TemperatureBelow 40°C recommended, avoid high temperature causing product degradation or color deepening Environment RequirementCool, dry, well-ventilated area Container ConditionKeep sealed to prevent moisture absorption and ingress of foreign matter After OpeningRe-seal opened containers tightly and store upright to prevent leakage Substances to AvoidAvoid contact with incompatible materials such as strong oxidizers Fire Source ManagementKeep away from heat, sparks, and open flame (flash point >149°C) Reference Shelf LifeTypically 24 months under unopened conditions, refer to product COA Application Suggestions For optimal performance, please pay attention to the following scenarios: Pre-use Inspection: Observe the product appearance before use. Normal appearance is an amber to brown viscous liquid. If obvious stratification, turbidity, or off-odor is detected, it is recommended to stop using even if within the shelf life. Batch Withdrawal: Use dry and clean tools to take the material, avoiding introducing moisture or impurities into the original container. Seal promptly after taking the material. Winter Storage: At low temperatures, the product viscosity will significantly increase, which is a normal physical phenomenon. Before use, the container can be warmed in an environment of 15-30°C; do not use open flame to heat directly. Precautions The product flash point is above 149°C (closed cup), but it should still be kept away from fire and high-temperature sources. Waste product and contaminated packaging should be disposed of in accordance with local regulations and requirements; do not drain into sewers or mix with household waste. The above shelf life information is based on general industry standards. Guoli Chemical reserves the final interpretation right for this parameter not marked in this database. Please refer to the COA accompanying the shipment.

Question 7

What safety precautions should be taken when using Span S-80?

Accepted Answer

When using Span S-80, focus on preventing skin, eye, and respiratory irritation; wear protective equipment throughout the operation and ensure good ventilation. Detailed Explanation Span S-80 (Sorbitan monooleate) is a non-ionic surctant, and its hazards primarily involve irritation to contact areas of the human body. According to the product safety data, this substance is classified as a skin irritant (Category 2, H315), a serious eye irritant (Category 2, H319), and may cause respiratory irritation (Category 3, H335). Fortunately, the product has no classification in terms of physical and chemical hazards, with a flash point above 149°C, making it not classified as a flammable liquid. Under normal storage conditions, fire risk is low, but it should still be kept away from high temperatures and open flames. In daily operations, personnel must wear complete personal protective equipment, including protective gloves, protective clothing, safety goggles, and ce shields. The work area should be well-ventilated to avoid inhaling product vapors or mist. After operation, thoroughly wash hands and any skin areas that may have come into contact with the product, and avoid contact with eyes, skin, and clothing. It is recommended to follow general industrial hygiene practices in the workplace and use explosion-proof ventilation and lighting equipment. In case of emergency: if skin contact occurs, immediately rinse with plenty of soap and water; if eye contact occurs, rinse continuously with water for several minutes, removing contact lenses if present, and seek medical attention if irritation persists; if discomfort arises from inhaling vapors, move to fresh air quickly; if ingested, do not induce vomiting, rinse mouth immediately and seek medical attention. In case of spillage, use inert absorbent materials such as sand to contain and collect, and do not discharge into drains. Key Safety Protection Points Protection AreaProtective MeasuresRisk Category SkinWear chemical-resistant gloves, protective clothingCategory 2 — H315: Causes skin irritation EyesWear safety goggles or ce shieldCategory 2 — H319: Causes serious eye irritation Respiratory SystemEnsure good ventilation, wear respiratory protection if necessaryCategory 3 — H335: May cause respiratory irritation Whole BodyThoroughly wash hands and contacted areas after operationAvoid prolonged or repeated contact Storage and Disposal Recommendations Storage Conditions: Store in a cool, dry, well-ventilated place, keep containers tightly closed. Storage temperature is recommended to be below 40°C to prevent product deterioration. Opened containers should be resealed and kept upright. Incompatible Materials: Avoid storing together with incompatible substances such as strong oxidizers. Fire Response: Flash point above 149°C (closed cup). In case of fire, use water fog, foam, dry powder, or carbon dioxide; firefighters should wear self-contained breathing apparatus. Waste Disposal: Dispose of product and contaminated packaging as hazardous waste in accordance with local regulations. Do not mix with household waste or discharge into water bodies or drains. Note Although Span S-80 is not classified as a flammable liquid, as its flash point is above 149°C, it generally does not form flammable vapors at normal operating temperatures. However, it is still recommended to keep away from heat sources, sparks, and open flames. When operating in laboratories or ctories, it is advised to conduct compounding and feeding operations under a fume hood or local exhaust ventilation. In case of a spill, do not rinse directly with water; use inert materials such as sand or vermiculite to absorb and collect, then seal and dispose of properly.

Question 8

How to use Span S-80? What is the recommended dosage?

Accepted Answer

Span S-80 is a low HLB value (4.3) water-in-oil nonionic emulsifier, which usually needs to be heated and dissolved in the oil phase before use. The recommended dosage is generally 1%~5% based on the total formulation weight, and the specific amount needs to be determined through experiments according to the formulation system. Detailed Instructions Span S-80 (Sorbitan monooleate) is a classic oil-soluble surctant produced by Guoli Chemical. At room temperature, it appears as an amber to brown viscous liquid (solidification point 10~12°C), is difficult to dissolve in water, but is easily soluble in mineral oils, vegetable oils, and most organic solvents. Its core function is to serve as a water-in-oil (W/O) emulsifier in oil-water systems, with an HLB value of only 4.3, especially suitable for stably dispersing the water phase in a continuous oil phase. Before use, it is recommended to add Span S-80 to the oil phase components of the formulation, heat to 40~60°C, and stir evenly until fully dissolved. If the product solidifies due to low ambient temperature, the container can be placed in a warm water bath to preheat and restore fluidity before use. Direct heating with an open flame is strictly prohibited. When preparing the emulsion, slowly add the water phase to the oil phase containing Span S-80 while undergoing high-speed stirring or homogenization to obtain a stable water-in-oil emulsion. To adjust the hydrophilic-lipophilic balance of the emulsification system, Span S-80 can be compounded with high HLB value Tween series (such as Tween T-80, HLB=15.0) to achieve the target HLB value. The determination of dosage needs to consider ctors such as the oil-to-water ratio, the type of emulsion required, and viscosity. Too low a dosage cannot form a stable emulsion, while too high a dosage may cause the system to be overly viscous or increase formulation costs. It is recommended to conduct gradient experiments (e.g., 0.5%, 1%, 2%, 5%) to observe emulsion stability and select the optimal dosage. Application Recommendations General recommended dosage in various fields (as weight percentage of total formulation): Application FieldTypical UseRecommended Dosage (wt%) Cosmetic Creams/LotionsW/O cold creams, sunscreens, massage oils1%~3% Food Emulsification SystemBaking ts, creamers, candies0.3%~1.0% Pharmaceutical PreparationsOintment bases, suppositories1%~5% Pesticide Emulsifiable ConcentratesEmulsifier for EC formulations (often compounded with other emulsifiers)2%~8% Industrial Lubricants/Rust Preventive OilsEmulsifier, dispersant0.5%~3% Textile Fiber OilsComponent of smoothing agents, antistatic agents0.5%~2% Plastic ProcessingInternal lubricant, antistatic agent0.2%~1.0% Note: The above dosages are industry general reference ranges. The optimal dosage should be determined through experiments based on specific formulation and process conditions. Precautions Compounding Recommendation: Using Span S-80 alone can only form W/O emulsions. To prepare O/W emulsions, it must be compounded with high HLB value emulsifiers (such as Tween series), and the ratio should be calculated by weighted average based on HLB values. Temperature Control: When preparing emulsions, it is recommended to keep the oil phase and water phase at the same temperature (usually 60~70°C). Excessive temperature difference can lead to instability of the primary emulsion. Protective Requirements: Span S-80 is classified as a skin/eye irritant (H315/H319). Protective gloves and goggles should be worn during operation, and ensure good ventilation. For specific safety matters, please refer to the Safety Data Sheet. Storage Conditions: The product should be stored in a tightly sealed container in a cool, dry place, with temperature below 40°C. Seal the container promptly after use to prevent moisture absorption or contamination.

Question 9

What are the main industries and processes where Span S-80 is used?

Accepted Answer

Span S-80 is widely used in seven major industries including cosmetics, food, pharmaceuticals, agrochemicals, industrial lubricants, textiles, and plastics, playing a key role as a W/O nonionic emulsifier and multifunctional additive. Detailed Description Span S-80 (sorbitan monooleate, CAS No.: 1338-43-8) is a classic nonionic surctant, valued for its excellent water-in-oil (W/O) emulsifying capability and broad formulation compatibility, making it an indispensable functional additive in many industrial fields. It appears as an amber to brown viscous liquid with a low HLB value (hydrophilic-lipophilic balance), giving it outstanding oil phase affinity and dispersing properties. The core value of Span S-80 lies in its unique molecular structure, which forms a stable intercial film at the oil-water interce, achieving efficient W/O emulsification at low dosages and significantly enhancing the stability and fineness of the emulsion system. At the same time, it also possesses multiple functions such as excellent dispersion, wetting, lubrication, and antistatic properties, and has good compatibility with various oils, waxes, and organic solvents, allowing flexible application in various formulation systems. More importantly, Span S-80 maintains stable surce activity under acidic, alkaline, and hard water conditions, enabling it to adapt to various harsh industrial environments. This is a key reason for its long-standing popularity across so many industries. Main Application Industries and Processes Industry Specific Process/Product Function Cosmetics & Personal Care Skin creams, sunscreens, lotions, makeup Provides a stable W/O emulsified structure, giving the product good spreadability, moisturizing feel, and long-lasting hydration effect Food Industry Bakery ts, creamers, candies, chocolate Improves oil-water dispersion, enhances product texture and mouthfeel stability Pharmaceutical Preparations Ointment bases, suppositories, creams Helps uniformly distribute active pharmaceutical ingredients in hydrophobic matrices, enhances transdermal absorption, and improves formulation uniformity and stability Agrochemicals Pesticide emulsifiable concentrates (EC), emulsifiable concentrates Allows active ingredients to fully dissolve in organic solvents, spontaneously forming stable emulsions upon dilution, ensuring efficacy during field application Industrial Lubricants Rust preventive oils, cutting fluids, hydraulic fluids, and other petroleum-based products Improves compatibility between additives and base oils, maintains oil uniformity, and enhances rust protection and lubricating performance Textile Industry Fiber lubricants, spin finishes Acts as a smoothing and softening agent component, reduces fiber friction, prevents static electricity, and improves bric hand feel and spinnability Plastics & Polymers Internal lubricants in plastic processing, antistatic treatment Reduces surce resistance, eliminates static charge buildup, while improving mold release and surce gloss of the product Application Recommendations As a W/O emulsifier, Span S-80 is typically recommended to be used in combination with Tween series (e.g., Tween T-80). By adjusting the ratio of the two, emulsifying systems with different HLB values can be obtained, meeting various emulsification needs from pure W/O to O/W. In cosmetic cream formulations, the recommended dosage is usually 1%-5% of the system; in pesticide ECs, the usage is generally 5%-15%; in industrial lubricants, the recommended addition is 0.5%-3%. The specific dosage should be optimized according to the formulation system and process conditions. Precautions This product is an oil-soluble emulsifier. During preparation, it is recommended to first dissolve Span S-80 in the oil phase, then slowly add the water phase for emulsification. Flash point >149 °C, but still keep away from high temperatures and open flames. Use explosion-proof ventilation and lighting equipment. May cause skin and eye irritation (H315/H319). It is recommended to wear personal protective equipment such as protective gloves and safety goggles during handling. Storage temperature is recommended to be below 40 °C. Keep container tightly closed and store in a cool, dry, and well-ventilated area.

Question 10

What are the physicochemical technical parameters of Span S-80?

Accepted Answer

Span S-80 is a classic water-in-oil nonionic surctant with an HLB value of 4.3. Its core physicochemical parameters involve multiple dimensions such as acid value, saponification value, hydroxyl value, iodine value, viscosity, and density. Detailed Description Span S-80 (CAS number: 1338-43-8) has the chemical name sorbitan monooleate, with the molecular formula C24H44O6 and a molecular weight of 428.61. The product appears as an amber to brown viscous liquid at room temperature (melting point 10~12°C) and exhibits excellent water-in-oil (W/O) emulsifying ability. Its molecular structure contains ester bonds and hydroxyl groups, giving the product unique lipophilic characteristics, but also resulting in poor alkali resistance—under strong alkaline conditions, the ester bonds can be hydrolyzed and broken. This product has an active content of ≥98%, with the main component being monoester (content ≥80%), diester content ≤15%, and free alcohol ≤1.0%. It is difficult to dissolve in water but soluble in various oils and organic solvents, making conventional aqueous pH determination unsuitable for this product. In terms of chemical stability, the product is stable under normal storage conditions but should avoid contact with strong acids, strong bases, and prolonged high-temperature heating. The recommended storage temperature is below 40°C. As a functional surctant, the surce activity parameters of Span S-80 are also noteworthy. Its critical micelle concentration (CMC) is approximately 2.5×10−5 mol/L (in water at 25°C), and the surce tension at 1% concentration in liquid paraffin is about 30 mN/m. The product has low foam, weak permeability, and low hygroscopicity. These characteristics make it perform excellently in oil-based systems—it can be used independently as a primary emulsifier or often combined with Tween series (such as Tween-80) to adjust the HLB value, meeting different formulation requirements. Technical Parameters Parameter CategoryParameter NameSpecification/Value Basic InformationChemical NameSorbitan Monooleate CAS Number1338-43-8 AppearanceAmber to brown viscous liquid Ionic TypeNonionic Chemical Characteristic IndicatorsAcid Value≤10 mg KOH/g Saponification Value145~160 mg KOH/g Hydroxyl Value200~240 mg KOH/g Iodine Value65~85 g I₂/100g Unsaturation0.26~0.34 mol/100g HLB Value4.3 Physical Characteristic IndicatorsDensity0.98~1.05 g/cm³ Kinematic Viscosity (25°C)1000~2000 mm²/s Refractive Index (20°C)1.476~1.478 Melting Point10~12°C Flash Point (Closed Cup)>150°C Surce Activity ParametersSurce TensionApprox. 30 mN/m (1% in liquid paraffin) CMCApprox. 2.5×10⁻⁵ mol/L (in water at 25°C) Quality IndicatorsActive Content≥98% Moisture≤1.5% Monoester Content≥80% Heavy Metals (as Pb)≤10 mg/kg Arsenic (As)≤2 mg/kg Application Recommendations Span S-80 has an HLB value of only 4.3, making it a typical lipophilic emulsifier, particularly suitable for water-in-oil emulsification systems. In cosmetic creams, sunscreens, and color cosmetic formulations, the recommended dosage is generally 1%~5% of the oil phase weight; in pesticide emulsifiable concentrate formulations, as an emulsifying dispersant, the recommended addition amount is 3%~8%; in the food field (E494), it can be used in bakery ts and non-dairy creamer systems. Due to its low HLB value when used alone, it is often compounded with higher HLB emulsifiers (such as the Tween series) to achieve a wider range of emulsification applicability. Precautions Operational Protection: This product is classified as Skin Irritant Category 2 and Eye Irritant Category 2. Protective gloves, safety goggles, and protective clothing must be worn during operation. Ensure good ventilation in the workplace to avoid inhaling vapors or mists. Storage Conditions: Store in a cool, dry, well-ventilated place. The container must be tightly sealed. The recommended storage temperature is below 40°C, away from strong oxidizers, strong acids, and strong bases. Alkali Resistance Limitations: The ester bonds in the product molecules can undergo hydrolysis under strong alkaline conditions, making it unsuitable for formulation systems with high alkalinity. Sediment Handling: The product has a low melting point (10~12°C). Solidification or stratification may occur at low temperatures. Before use, it can be appropriately heated to restore a uniform state, but prolonged high-temperature heating should be avoided. Data Explanation: All the above technical parameters are sourced from the Guoli Chemical product database. Parameter determination is based on standard product batches. Specific values are subject to the batch inspection report.

Span S-80 (Sorbitan Monooleate)

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Property	Value
CAS No.	1338-43-8
Molecular Formula	C24H44O6
Appearance	Yellow to amber
Ionic Type	Nonionic
Avg. Molecular Weight	428.61
Cloud Point	N/A (poorly water-soluble; cloud point not applicable)
Active Content	≥98%
pH Value(1%)	N/A (insoluble in water; pH cannot be measured in aqueous solution)
pH Value(5%)	N/A (insoluble in water; pH cannot be measured in aqueous solution)
Iodine Value	65~85
Solubility	Soluble in oils and organic solvents; hardly soluble in water
Surface Tension	~30 mN/m (1% in liquid paraffin)
CMC	~2.5×10⁻⁵ mol/L (25°C in water)
Acid Value	≤10
Saponification Value	145~160
Hydroxyl Value	200~240
Moisture	≤1.5
Density	0.98~1.05
Kinematic Viscosity	1000~2000 mm²/s (25°C)
Refractive Index	1.476~1.478 (20°C)
Flash Point	>150°C (closed cup)
Hygroscopicity	Low hygroscopicity
Chemical Stability	Stable; avoid strong acids/alkalis and prolonged heating
Amine Value	N/A (no amine groups)
Penetration	Weak (oil-soluble surfactant)
Foam Property	Low foam
Alkali Resistance	Poor; ester bonds hydrolyzed by alkali
Unsaturation	0.26~0.34 mol/100g
Viscosity	Viscous liquid, ~1000-2000 mPa·s
Melting Point	10~12
Monoester Content	Primarily monoester; content ≥80%
Diester Content	≤15%
Low Shear Viscosity	Comparable to kinematic viscosity; ~1000-2000 mPa·s
Solid Content	≥98% (active basis)
Free Alcohol	≤1.0% (such as sorbitan, etc.)
Heavy Metal	≤10 mg/kg
Arsenic	≤2 mg/kg

Span S-80 (Sorbitan Monooleate)

Product Details

Applications

Properties

Safety

Product Overview

Performance Features

Packaging and Storage

Span / Sorbitan Ester Applications

Product Properties

Safety

GHS

Handling

Storage

First Aid

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