Question 1

Is Span S-60 harmful to the human body? Does it have an impact on the environment?

Accepted Answer

Span S-60 is a low-toxicity substance. Its main risk to humans is mild irritation, and it has no clear hazardous classification to the environment. Under standard use, it is relatively safe. Detailed explanation Span S-60 (Sorbitan monostearate) has extremely low overall toxicity. According to safety data provided by Guoli Chemical, its rat oral LD₅₀ is greater than 15,000 mg/kg, placing it in the low-toxicity category. Therefore, this product is widely used in fields directly related to human health such as food (as emulsifier E491), cosmetics, and pharmaceuticals, and its safety has been widely recognized by international regulatory systems. The main risk to humans centers on local irritation rather than systemic toxicity. Direct contact may cause mild skin irritation (GHS Category 2, H315) and serious eye irritation (GHS Category 2, H319). Inhalation of dust or mist may cause respiratory irritation (GHS Category 3, H335). These irritation reactions are usually temporary and reversible. Wearing gloves, goggles, and a dust mask during operation can provide effective protection. In terms of the environment, Span S-60 is not classified as hazardous to the environment under GHS, and its ecotoxicity risk is low. Nevertheless, during daily use and industrial discharge, direct release into soil, waterways, or drainage systems should be avoided. Spills should be collected and disposed of according to local regulations, and not discarded with household waste. Safety parameters Safety indicatorParameter Acute oral toxicity (rat LD₅₀)> 15,000 mg/kg (low toxicity) Skin irritationGHS Category 2 — H315: Causes skin irritation Eye irritationGHS Category 2 — H319: Causes serious eye irritation Inhalation riskGHS Category 3 — H335: May cause respiratory irritation Flash point (closed cup)> 149 °C (non-flammable under normal use conditions) Environmental hazard classificationNot classified as hazardous to the environment Food additive numberE491 (recognized by the International Food Codex) Application recommendations Given its low toxicity and high safety, Span S-60 has a long history of safe use in the following areas: Food industry: Used as emulsifier E491 in margarine, ice cream, pastries, chocolate, etc., with dosage following the limits of national food additive regulations. Cosmetics: Used in creams, lotions, sunscreens, etc., forming a protective film on the skin with moisturizing effects. Pharmaceuticals: Used as suppository base and drug carrier, with good formability and sustained release effects. Industrial uses: Used in textile oils, pesticide emulsifiers, plastic anti-fog agents, and other non-direct human contact applications, with even lower safety risks. Precautions Personal protection: Wear nitrile or neoprene gloves, chemical safety goggles, and if dust is generated, wear a particulate respirator (e.g., N95 mask). Working environment: Maintain good ventilation. Do not eat, drink, or smoke in the work area. Wash hands and exposed areas thoroughly after operation. First aid measures: In case of skin contact, wash with plenty of water and soap for at least 15 minutes; for eye contact, rinse with flowing water for at least 15 minutes and seek medical attention immediately; if inhaled, move to fresh air; if swallowed, rinse mouth and do not induce vomiting. Storage conditions: Recommended storage temperature below 35°C, avoid direct sunlight, keep away from strong oxidizers, keep container tightly closed to prevent moisture. Disposal: Dispose of in accordance with local regulations at licensed waste treatment cilities. Do not mix with household waste.

Question 2

What should I do if problems occur during the use of Span S-60? How to obtain technical support?

Accepted Answer

If you encounter problems when using Span S-60 (Span 60), please first investigate according to the type of problem: For emergencies involving personal safety, leakage, etc., strictly follow the emergency treatment in the Safety Data Sheet (SDS); for technical issues such as formulation process and product performance, it is recommended to record the problem phenomenon in detail and then directly contact the technical team of Haian Guoli Chemical Co., Ltd. for professional support. Detailed Explanation Span S-60 (Sorbitan monostearate), as a classic non-ionic W/O emulsifier, has stable performance under normal operating conditions. If abnormalities occur during use, preliminary diagnosis and treatment can usually be carried out from two dimensions: "Safety Emergency" and "Technical Application". Safety issues are urgent and require immediate response; technical issues are often related to formulation systems, operating processes or storage conditions and require systematic analysis. For safety contact incidents, Span S-60 is a low-toxicity substance (rat oral LD₅₀ > 15,000 mg/kg), but it may still cause irritation to skin, eyes and respiratory tract. In the event of a large spill, personal injury or fire, the corresponding emergency procedures should be initiated immediately. For problems at the formulation application level, such as emulsion stratification, rough paste, low dispersion efficiency or difficulty in dissolving the product, they often originate from mismatched HLB value, improper oil phase selection, feeding temperature not reaching melting point requirements, or combination with strong acids and alkalis. Since there is no direct client-cing technical support hotline or online customer service link available in the official product database of Guoli Chemical, the best way to obtain official technical guidance is to directly contact your purchasing channel or the business contact person of Haian Guoli Chemical Co., Ltd.. It is recommended that before seeking help, you prepare the product batch number, problem description, formulation system and operating process parameters so that the technical engineer can quickly locate the problem. Common Problem Diagnosis and Solution Ideas Based on the product characteristics of Span S-60 (HLB value about 4.7, melting point 52~57℃, acid value ≤10, saponification value 145~160), the following are emergency treatment plans and debugging suggestions for several typical usage problems: I. Safety and Emergency Problems Skin contact or irritation: Immediately remove contaminated clothing and rinse with plenty of water and soap for at least 15 minutes. If irritation persists, seek medical attention. Eye contact: Immediately rinse gently with running water or normal saline for at least 15 minutes, while lifting the eyelids. Be sure to seek medical attention immediately. Dust inhalation discomfort: Quickly move to fresh air and keep breathing unobstructed. If coughing or wheezing symptoms persist, seek medical attention. Small spill: Absorb with inert absorbent material (e.g., paper towels, cloth), collect in a closed container for disposal, and avoid dust generation. II. Technical Application Problem Troubleshooting 1. Why is the emulsion unstable, easy to stratify or demulsify? Key investigation: Span S-60 is a lipophilic emulsifier, which is only suitable for preparing W/O type emulsions when used alone. If used in an O/W system, it must be compounded with high HLB value emulsifiers (such as Tween series). It is recommended to calculate the required HLB value according to the polarity of the oil phase, or conduct gradient experiments with different ratios (e.g., Span-Tween combination). At the same time, ensure that Span S-60 is fully dissolved and dispersed in the oil phase before adding. 2. Why is Span S-60 difficult to dissolve and has a grainy texture in the paste? Key investigation: This product is a waxy solid with a melting temperature range of 52~57℃. It must be added to the oil phase preheated to above 60℃ and stirred to dissolve in order to obtain a transparent and uniform dispersion. Adding directly to a low-temperature system will cause the emulsifier to precipitate and crystallize, resulting in a rough finished product. 3. Why does the product agglomerate, darken in color or decline in performance? Key investigation: The storage environment may be improper (e.g., too high temperature or moisture absorption). It is recommended that the storage temperature be below 35℃, stored in a cool and dry place, and avoid direct sunlight. If the packaging bag is not completely used after opening, the inner bag mouth must be tightly tied immediately to prevent moisture absorption. If the product hardens at low temperature, it is a normal physical change; it can restore its properties after returning to room temperature before use, without affecting quality. How to Obtain Professional Technical Support from Guoli Chemical This product knowledge base currently does not include a real-time online customer service system or direct technical hotline, but you can seek in-depth technical support through the following channels: Contact Business Manager: Contact the business personnel or distributor from whom you purchased this batch of Span S-60. They can connect with the internal technical team of Guoli Chemical most quickly. Official Website or Platform: Visit the official website of Haian Guoli Chemical Co., Ltd., check the "Contact Us" or "Technical Service" section, leave a message for consultation or call the company landline. Prepare Key Information: To improve communication efficiency, please be sure to provide: Product batch number and purchase date, Complete base formula and feeding process (temperature, stirring speed), Specific ilure phenomenon description (e.g., stratification, agglomeration, abnormal color) and Storage environment description. Precautions Keep away from strong oxidizers, avoid prolonged high-temperature co-heating with strong acids or strong alkalis, otherwise it may lead to ester bond hydrolysis. Conventional packaging specifications are 20kg/25kg woven bags, lined with polyethylene moisture-proof bags. Handle with care to prevent package damage during transportation. Strictly comply with GHS classification requirements. Wear chemical protective gloves and goggles during operation, and maintain good ventilation in the workplace.

Question 3

How to purchase Span S-60? What is the minimum order quantity?

Accepted Answer

The official purchasing channel for Span S-60 is to directly contact the Guoli Chemical sales team. The specific minimum order quantity needs to be confirmed with the sales department. Detailed Description Span S-60 (Sorbitan Monostearate) from Hai'an County Guoli Chemical Co., Ltd. is a standardized industrial product, with conventional packaging specifications of 20kg woven bags or 25kg woven bags. Product prices fluctuate due to ctors such as raw material market conditions, order quantity, payment methods, and logistics arrangements. Therefore, the company adopts an offline quotation model without fixed online pricing, ensuring customers receive accurate procurement solutions. To obtain the latest quotation, confirm the minimum order quantity (MOQ), and check inventory availability, please contact the Guoli Chemical sales department directly. You can reach the sales team via the contact information published on the company's official website or by calling the sales hotline. Provide your required quantity and application scenario, and the sales engineer will match you with the optimal cooperation plan. Procurement Process Suggestions To improve communication efficiency, it is recommended to prepare the following information before contacting sales to quickly obtain an accurate quotation: Estimated Purchase Quantity: Such as trial order quantity for the first order, monthly or annual planned usage (in kilograms or tons). Target Application Field: Such as cosmetics, food, pharmaceuticals, pesticide emulsification, or textile oils. Different industries may require different technical specifications. Delivery Address: To calculate logistics costs and determine delivered duty paid (DDP) or ex-works price. Packaging Preference: Deult packaging is 20kg or 25kg woven bags. Whether specific packaging forms or customized labels are needed. Technical Parameters When contacting sales, you can reference the following key indicators to ensure the corresponding grade product is provided: Parameter ItemSpecification AppearanceWhite to light yellow waxy solid CAS Number1338-41-6 HLB Value4.7 Active Content≥98% Hydroxyl Value (mg KOH/g)230~270 Saponification Value (mg KOH/g)145~160 Melting Point52~57°C Moisture≤1.5% Conventional Packaging20kg woven bag, 25kg woven bag Application Suggestions Span S-60 is a classic W/O non-ionic emulsifier. If your formulation requires an emulsification system with higher HLB values, it can be compounded with Tween series (such as Tween-60, Tween-80). Guoli Chemical also supplies the full range of Tween products, enabling one-stop procurement for designing composite emulsification schemes with gradient HLB values. Notes The above packaging specifications and price information are sourced from the Guoli Chemical product database (Last updated: 2026-06-10). There is currently no publicly available data on minimum order quantity. Actual transaction conditions (including but not limited to minimum order quantity, discounts, freight, etc.) shall be subject to the terms of the purchase and sales contract. The storage temperature for Span S-60 is recommended to be below 35°C. Solidification may occur at low temperatures; allow it to return to room temperature before use.

Question 4

Does Span S-60 meet environmental requirements? Can a test report be provided?

Accepted Answer

Span S-60 meets environmental requirements under compliant use and disposal; no online test report is available on the website, please contact sales to obtain batch COA Environmental compliance analysis Span S-60 meets environmental requirements under normal use and compliant disposal conditions. According to the clear classification in the Safety Data Sheet of Guoli Chemical, the ecotoxicity: Not classified as hazardous to the environment. This means that under the current evaluation standards of the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), Span S-60 itself is not considered to cause acute or long-term harm to aquatic environments (e.g., fish, algae, daphnia). In addition, the product has very low acute oral toxicity (rat oral LD₅₀ > 15 000 mg/kg) and is widely approved as a food additive (E491) and pharmaceutical excipient, which indirectly confirms its high biosafety. However, in the event of a large-scale spill, strict measures must still be taken to prevent its entry into drainage systems or natural water bodies, to avoid local oxygen depletion due to physical film-forming effects or impacts on water sensory properties. During waste disposal, Span S-60 itself does not pose risks of persistent organic pollutants (POPs) or heavy metal accumulation, and can be incinerated or landfilled in accordance with local regulations. If incinerated with complete combustion, it mainly produces carbon dioxide and water; incomplete combustion may generate harmful gases such as carbon monoxide, which must be handled by qualified institutions in a standardized manner. About the test report The current online product database does not provide pre-generated PDF or electronic test reports. The ways to obtain the ctory batch test report (COA) are as follows: You can directly send an email or call the sales or customer service department of Hai'an Guoli Chemical Co., Ltd., provide the batch number of the desired product, and request the official ctory inspection report. The report will detail the actual measured data for that batch. As a reference, our ctory inspection strictly follows enterprise standards, and samples are regularly sent to third-party institutions for testing. You can refer to the routine technical parameters listed in the table below to understand the core indicators of our quality control: Routine ctory inspection core parameters Test itemSpecification standard AppearanceWhite to light yellow waxy solid Active content≥98% Acid value (mg KOH/g)≤10 Saponification value (mg KOH/g)145~160 Hydroxyl value (mg KOH/g)230~270 Moisture (%)≤1.5 Iodine value (g I₂/100g)≤2 Heavy metals (as Pb, mg/kg)≤10 Arsenic (As, mg/kg)≤3 Melting point (°C)52~57 HLB valueApprox. 4.7 Environmental use and disposal recommendations Spill handling: In case of a small spill, use inert absorbent materials (e.g., sand, vermiculite) to cover and collect into a sealed container to prevent dust dispersion. Do not flush with water directly, avoid entry into sewers or soil. Wastewater treatment: Industrial wastewater containing this product should be collected in the enterprise's wastewater treatment plant and treated by biochemical processes such as activated sludge method before discharge, as Span S-60 has good biodegradability. Empty drums/packaging bags: The inner wall of the packaging container may have product residues; do not discard or repurpose arbitrarily. Entrust qualified environmental protection units for recycling or compliant disposal. Precautions Although the product itself has low environmental risk, for occupational health, note that this product is a mildly irritating substance, may cause skin and eye irritation (H315, H319). Wear gloves and goggles during operation; if contact with eyes or skin occurs, rinse immediately with plenty of water.

Question 5

What are the advantages of Span S-60 compared to similar products?

Accepted Answer

According to the technical data from Guoli Chemical, the core advantage of Span S-60 lies in its role as a classic non-ionic surctant, providing an **optimal balance between excellent water-in-oil (W/O) emulsifying performance, high safety, and wide compatibility**, making it a top choice in multiple fields from food and pharmaceuticals to industrial applications. In detail, compared to similar products, its advantages are mainly reflected in the following aspects: 1. **Precise W/O Emulsification Expertise** Span S-60 has a very low Hydrophilic-Lipophilic Balance value (**HLB value: 4.7**), indicating strong lipophilicity. When constructing water-in-oil emulsions, it firmly adsorbs at the oil-water interce, forming a tough intercial film that yields creams, lotions, and other products with a fine texture and extremely high stability. This is its most core and hard-to-replace performance. 2. **Excellent Compatibility and Formulation Flexibility** Span S-60 does not work alone; its strength lies in its ability to be freely combined with hydrophilic emulsifiers (such as the Tween series from Guoli Chemical). By adjusting the ratio of Span to Tween, formulators can precisely design composite emulsifier systems with the required HLB value, thereby stabilizing different oil phases, offering unlimited possibilities for developing diverse and customized formulations. 3. **Superior Chemical Stability and Mildness** As a non-ionic surctant, it remains stable over a wide pH range, in hard water, and in electrolyte solutions. While the ester bonds in its chemical structure can hydrolyze under strong alkaline conditions, from an application perspective, its **acid value (≤10 mgKOH/g)** and **iodine value (≤2 gI₂/100g)** are extremely low, indicating high purity, few impurities, good saturation, and resistance to oxidative rancidity, which gives formulations a longer shelf life. 4. **Proven High Safety** This is a key advantage that distinguishes Span S-60 from many industrial emulsifiers. Its rat oral acute toxicity **LD₅₀ > 15,000 mg/kg** classifies it as practically non-toxic. Therefore, it is approved as a food additive (E491) and widely used in pharmaceuticals (e.g., suppository bases) and cosmetics, with a complete and reliable safety record. 5. **Significant Versatility** Beyond its core emulsifying effect, Span S-60 also possesses dispersing, solubilizing, lubricating, and other functions. For example, it serves as an anti-fogging agent in plastic films and as a smoothing and antistatic agent in the textile industry. **Key Quality Indicator Comparison** To visually demonstrate its performance, below are the key technical parameters of Guoli Chemical's Span S-60: | Technical Parameter | Specification | Performance Interpretation and Advantage | | :--- | :--- | :--- | | **Appearance** | White to light yellow waxy solid | Good physical form, easy for weighing and feeding. | | **HLB Value** | **4.7** | Clearly indicates W/O type emulsifier, high specificity. | | **Monoester Content** | **≥80%** | High monoester content ensures excellent emulsifying efficiency and intercial film strength. | | **Acid Value** | **≤10 mgKOH/g** | Low acid value means high purity and low irritation, minimal impact on the formulation system. | | **Saponification Value** | **145~160 mgKOH/g** | Precise esterification degree ensures stable performance between batches. | | **Hydroxyl Value** | **230~270 mgKOH/g** | Reflects the number of active hydroxyl groups, a key site for reactions or associations with other chemicals. | | **Moisture** | **≤1.5%** | Extremely low moisture content ensures product stability during storage, resistant to hydrolysis. | | **Heavy Metals/Arsenic** | **≤10 mg/kg / ≤3 mg/kg** | Strict control of harmful elements, meeting high safety standards such as food grade and pharmaceutical grade. | **Application Suggestions** * **Typical Dosage**: As the main emulsifier, the conventional dosage in the oil phase is **2% - 5%**. If combined with the Tween series (e.g., Tween 60), the total amount is similar, and the ratio is adjusted to suit different oil phases. * **Usage Method**: Given its melting point of **52~57℃**, it is recommended to first add Span S-60 to the oil phase, heat to **60-70℃** to completely melt and stir evenly, then slowly add the water phase to the oil phase for homogenization and emulsification. **Precautions** * **Storage**: Should be stored sealed in a cool, dry place, with temperature **recommended below 35℃**, avoiding direct sunlight and moisture. * **Personal Protection**: Although it is a low-toxicity substance, gloves and goggles should be worn during operation to avoid minor irritation of the skin, eyes, and respiratory tract by its dust. In case of contact, rinse immediately with plenty of water. In summary, Guoli Chemical's Span S-60 stands out among similar products due to its **specialized W/O emulsifying ability, high safety, flexible combinability, and stable, controllable high quality**, making it an ideal choice for those seeking formulation stability and safety.

Question 6

How to store Span S-60? What is its shelf life?

Accepted Answer

Span S-60 should be stored sealed in a cool, dry, and well-ventilated place. The recommended temperature is below 35°C and keep away from light; the shelf life is typically 12 to 24 months. Detailed Description Span S-60 (Sorbitan monostearate) is a chemically stable nonionic surctant. Proper storage is crucial for maintaining its core properties such as emulsification and dispersion. Its waxy solid physical form makes it somewhat sensitive to temperature, humidity, and light. Improper storage may lead to caking, color deepening, or increased acid value, thereby affecting the formulation performance. According to the safety data sheet (SDS) provided by Guoli Chemical, the product should be stored in a cool, dry, and well-ventilated place, and the container must be kept tightly sealed to prevent moisture absorption and contamination. The original packaging is usually a woven bag or kraft paper bag lined with polyethylene. If not used up after opening, the inner bag mouth should be tightly tied. The product should be kept away from incompatible substances such as strong oxidizers and should comply with the stacking layer limits on the packaging to prevent damage to the bottom packages due to pressure. Technical Parameters Storage Condition ItemSpecific Requirement Storage EnvironmentCool, dry, well-ventilated Suitable TemperatureBelow 35°C (may solidify at low temperatures, allow to return to room temperature before use) Light RequirementAvoid direct sunlight Package SealingKeep container tightly sealed; tie inner bag mouth after opening Substances to AvoidStrong oxidizers (e.g., high-concentration peroxides, hypochlorites) Shelf LifeNo accurate data in database Application Recommendations In applications with high safety requirements such as cosmetics, food, and pharmaceuticals, it is recommended to follow the strict "first in, first out" inventory management principle. For products stored long-term, sample and test key indicators before use, such as acid value (specification limit ≤10 mgKOH/g), saponification value (145~160 mgKOH/g), and hydroxyl value (230~270 mgKOH/g). Ensure these parameters are still within the acceptable range before using in large-scale production to guarantee the stability of the final product quality. Precautions Temperature fluctuation: The melting point of the product is 52~57°C. The storage temperature should not approach this range and must not exceed the melting point, otherwise the product will melt and cake, making it difficult to weigh and use. Shelf life reference: Although the Guoli Chemical product database does not have accurate shelf life data for this product, according to industry common standards, under recommended storage conditions, the shelf life of Span S-60 is typically 12 to 24 months. It is recommended to refer to the batch inspection report and label on the product packaging. Check before use: If the product shows significant discoloration, odor, or caking that cannot be dispersed, discontinue use even if the expiry date has not been reached.

Question 7

What safety precautions should be taken when using Span S-60?

Accepted Answer

Span S-60 is a low-toxicity substance, but precautions against skin, eye, and respiratory tract irritation are still necessary. Personal protective equipment such as gloves and safety goggles must be worn during operation, and use in a well-ventilated area is required. Detailed Explanation Span S-60 (sorbitan monostearate) has an oral LD₅₀ in rats greater than 15,000 mg/kg, classifying it as a low-toxicity substance with low acute toxicity risk. However, according to GHS classification criteria, this product is classified as Skin Irritant Category 2 (H315: Causes skin irritation), Serious Eye Damage/Eye Irritation Category 2 (H319: Causes serious eye irritation), and Specific Target Organ Toxicity - Single Exposure Category 3 (H335: May cause respiratory irritation). This means that direct contact or inhalation of dust may still cause some discomfort and irritation to operators. In routine operations, the product itself is non-flammable under normal use conditions (closed cup flash point > 149 °C) and has low physicochemical hazards. However, it should be noted that in the event of combustion or high-temperature decomposition, carbon monoxide, carbon dioxide, and irritating or toxic vapors and fumes may be generated. Additionally, the product may solidify at low temperatures; it should be brought to room temperature before use to ensure material fluidity and operational convenience. Personal Protection and Operational Guidelines Personal Protective Equipment Requirements Respiratory Protection: If dust or vapor is generated during operation and ventilation is insufficient, wear a certified particulate respirator (e.g., N95 mask) to avoid inhalation of aerosols or dust. Hand Protection: Wear certified chemical-resistant gloves (e.g., nitrile rubber, chloroprene rubber) and regularly check glove integrity, determining replacement frequency based on working conditions. Eye/ce Protection: Wear chemical safety goggles or a ce shield to prevent product from splashing into the eyes. Skin and Body Protection: Wear conventional work protective clothing to avoid prolonged or repeated skin contact. Contaminated work clothing should be washed before reuse. Operating Condition Requirements Ensure the workplace has adequate general ventilation or local exhaust to maintain airborne dust or vapor concentrations below occupational exposure limits. Operators should receive training on the hazardous characteristics of this substance and safe operating procedures. Eating, drinking, or smoking is prohibited in the work area. After operation, thoroughly wash hands and any skin areas that may have come into contact. Whenever possible, operate in a closed system or use automated processes to minimize human contact. If not feasible, provide local exhaust at openings. Storage Precautions Storage ConditionSpecific Requirements Storage EnvironmentCool, dry, well-ventilated area; keep container tightly closed to prevent moisture and foreign matter ingress Suitable TemperatureRecommended below 35°C, avoid extreme temperatures and temperature fluctuations; product may solidify at low temperatures, bring to room temperature before use Light ProtectionAvoid direct sunlight Away from Incompatible SubstancesKeep away from strong oxidizing agents (e.g., high-concentration peroxides, hypochlorites) Packaging MaterialsOriginal containers are typically paper bags with polyethylene lining, multi-layer kraft paper bags, or fiber drums; after opening, tightly close the inner bag if not fully used Stacking LimitsComply with the stack height limit indicated on the packaging to prevent damage to bottom containers from pressure Emergency Response Measures First Aid Measures Inhalation: Move the affected person to fresh air and maintain a position comfortable for breathing. If respiratory irritation symptoms persist or worsen (e.g., coughing, wheezing), seek medical attention immediately. Skin Contact: Immediately remove all contaminated clothing and rinse the affected area with plenty of water and soap for at least 15 minutes. If skin irritation or rash occurs, seek medical attention. Wash contaminated clothing before reuse. Eye Contact: Immediately hold eyelids open and rinse continuously and gently with flowing water or saline solution for at least 15 minutes, occasionally lifting upper and lower eyelids to ensure thorough rinsing. Remove contact lenses (unless they are stuck to the eye and difficult to remove). Regardless of the severity of irritation symptoms, seek medical attention immediately after rinsing. Ingestion: Rinse the mouth thoroughly with water; do not induce vomiting (unless instructed by medical personnel). If the affected person is conscious, give a small amount of water to dilute. If discomfort occurs, seek medical attention immediately and show this safety instruction or label. Spill Handling Non-emergency personnel should evacuate immediately; only trained personnel with appropriate personal protective equipment should handle the spill. Avoid letting the spill or cleaning waste enter drains, sewers, soil, or natural water bodies. Small spills: Absorb with paper towels, cloths, or inert absorbent material and collect in a closed container for disposal. Large spills: Dike or contain to prevent spread; use a vacuum cleaner with an explosion-proof feature or non-sparking tools to recover material into a dedicated waste container. Residues can be rinsed with a small amount of water and detergent, but collect and properly dispose of the rinse liquid. Remarks Waste disposal should follow local, national, and regional regulations; use licensed waste treatment cilities for incineration or landfill; do not dispose of with household waste. Empty containers may contain product residues and must follow the same safe handling and disposal procedures as the product itself; do not use for storing other materials without thorough cleaning. For detailed safety data and operating instructions, please refer to the product Safety Data Sheet (SDS).

Question 8

How to use Span S-60? What is the recommended dosage?

Accepted Answer

The usage of Span S-60 varies depending on the application field; as a water-in-oil (W/O) type emulsifier, the key point is to first dissolve it in hot oil phase and then participate in emulsification. The recommended dosage is usually 1%~10% of the total formula (specific amount depends on the system). Detailed Explanation Span S-60 (Sorbitan Monostearate) is a nonionic surctant that appears as a white to yellowish waxy solid at room temperature, with a melting point of 52~57°C and an HLB value of only 4.7, making it a typical lipophilic emulsifier. According to the Guoli Chemical product database, this product is soluble in hot oil and organic solvents but insoluble in water. Therefore, correct dissolution and addition sequence are crucial: generally, Span S-60 should be added to the oil phase, heated to 60~70°C to completely melt and stir evenly, then mixed with the water phase for emulsification. To prepare O/W emulsions, Span S-60 is often used in combination with Tween series (e.g., Tween-60, HLB value 14.9), adjusting the ratio to achieve the target HLB value. In specific operation, it is recommended to heat the oil phase (containing Span S-60) and water phase separately to 70~75°C, then slowly add the water phase to the oil phase under high-speed stirring (for W/O type), or vice versa add the oil phase to the water phase (for O/W type if compounded with Tween). After emulsification, cool to room temperature with continuous stirring to obtain a stable emulsion system. High-shear homogenizers can significantly improve emulsification efficiency and product stability. This product is chemically stable, resistant to acids, alkalis, and hard water, but may hydrolyze in the presence of strong alkalis, so compatibility should be considered in alkaline formulations. It should also avoid prolonged exposure to high temperatures above 150°C to prevent decomposition and discoloration. The effective content of Span S-60 provided by Guoli Chemical is ≥98%, with monoester content ≥80%, ensuring stable and reliable product quality. Technical Parameters ParameterValue (Data source: Guoli Chemical product database) AppearanceWhite to yellowish waxy solid HLB value4.7 Melting point52~57°C Effective content≥98% Monoester content≥80% Acid value≤10 mg KOH/g Saponification value145~160 mg KOH/g Hydroxyl value230~270 mg KOH/g Water content≤1.5% Iodine value≤2 g/100g pH of 5% aqueous dispersion5.0~7.0 Flash point (closed cup)＞149°C DensityApprox. 1.0 g/cm³ SolubilitySoluble in hot oil and organic solvents, insoluble in cold water Application Recommendations The following are typical usage methods and recommended dosage ranges for various industries (dosage data are from general industry practices; specific amounts should be determined through experiments based on the formulation system): Cosmetics (creams/lotions): As a primary W/O emulsifier, the recommended dosage is 2%~8% of the oil phase. For O/W emulsions compounded with Tween-60, the common ratio of Span-60 to Tween-60 is 1:3 to 1:5, with total emulsifier usage around 3%~6% of the formulation. Operation: dissolve Span S-60 in the oil phase, heat to 70°C, then mix with the water phase at the same temperature for emulsification. Food (margarine, pastries): According to GB 2760 and international standards, used as an emulsifier and stabilizer, the recommended dosage is 0.3%~1.0% (based on t content). It is often used in combination with other emulsifiers (e.g., glyceryl monostearate) for better results. Pharmaceutical suppository base: As a component of suppository base, the dosage of Span S-60 depends on the prescription, usually 5%~30% of the total base, combined with other base materials (e.g., cocoa butter, semi-synthetic glycerides) to adjust melting point and drug release rate. Textile lubricants: As a component of fiber lubricants, the recommended dosage is 3%~10% of the lubricant formulation, providing smoothness and antistatic properties. Agricultural film anti-fog additives: As an internal additive anti-fog masterbatch component, the recommended final content in the film is 0.5%~2% (based on resin weight), significantly reducing fog condensation in greenhouses. Pesticide emulsifiable concentrates: As an emulsifier component, the recommended dosage is 3%~8% of the emulsifiable concentrate formulation, often compounded with hydrophilic emulsifiers (e.g., Tween series or anionic emulsifiers) to achieve self-emulsifying properties upon dilution. Coatings and inks: As a pigment dispersant, the recommended dosage is 1%~5% of the pigment weight, added during the grinding stage to effectively prevent pigment agglomeration and floating. Plastic antistatic agents: As an internal additive antistatic agent, the recommended dosage is 0.5%~1.5% of the resin weight, reducing static electricity and dust adsorption on film surces. Note: The above dosage recommendations are general industry reference ranges. The Guoli Chemical product database does not contain precise dosage parameters for each application field. It is recommended that users determine the optimal dosage through a series of gradient experiments when developing new formulations. Precautions Dissolution operation: Span S-60 is a solid waxy substance. Before use, it must be fully melted in the oil phase by heating above 60°C. Do not add directly to cold water. Personal protection: This product may cause skin and eye irritation (GHS classification: Skin irritation Category 2, Eye irritation Category 2). Wear chemical protective gloves and goggles during operation, and avoid inhaling dust. Storage conditions: Store in a cool, dry, and well-ventilated area. Recommended temperature below 35°C, avoid direct sunlight and humid environment. After opening, tightly seal the inner bag to prevent moisture absorption and foreign matter entry. Incompatibilities: Although this product is chemically stable, avoid coexistence with strong oxidizing agents; may hydrolyze under strong alkaline conditions; in alkaline formulations...

Question 9

In which industries and processes is Span S-60 mainly used?

Accepted Answer

Span S-60 is widely used in seven major industries including food, cosmetics, pharmaceuticals, textiles, plastics, pesticides, and coatings & inks, with its core function serving as a W/O-type emulsifier, dispersant, and stabilizer. Detailed Description Span S-60 (sorbitan monostearate) is a classic nonionic surctant with CAS number 1338-41-6. Its molecular structure endows it with excellent water-in-oil (W/O) emulsifying ability, enabling it to form a strong intercial film at the oil-water interce to prepare stable W/O emulsion systems. At the same time, it exhibits good tolerance to acids, alkalis, and hard water media, maintaining stable performance over a wide pH range and in complex formulation environments. This makes it a versatile functional additive across industries and multiple process scenarios. With extremely low acute oral toxicity (rat oral LD₅₀ > 15,000 mg/kg) and good biocompatibility, Span S-60 is not only widely used in industrial fields but also permitted in products directly related to human health such as food, medicine, and cosmetics. In addition, Span S-60 can be compounded with hydrophilic surctants such as Tween series to flexibly adjust the HLB value, achieving precise design from W/O to O/W emulsion systems, greatly expanding its application boundaries. Detailed Industry and Process Application IndustryCore FunctionTypical Process & Application Scenarios Cosmetics & Personal CareW/O primary emulsifier or co-emulsifierEmulsification and stabilization of formulations such as creams, lotions, sunscreens, imparting a fine texture and good spreadability, and forming a protective film on the skin to provide moisturizing effects Food IndustryEmulsifier, StabilizerIn high-t foods such as margarine, ice cream, pastries, and chocolate, it prevents oil separation, improves texture, retards starch aging, and extends shelf life; complies with E491 food additive standard Pharmaceuticals & Health ProductsSuppository base, drug carrierMolding base for suppositories such as vaginal and rectal suppositories; promotes uniform drug dispersion and controlled release in oral and topical formulations, improving system stability and bioavailability Textile IndustryFiber oil component, softening finishing agentProvides smoothness, cohesion, and antistatic properties in synthetic fiber spinning oils; reduces processing friction in bric softening finishing processes, improving hand feel Plastics IndustryAnti-fogging agent, antistatic agentInternal additive component in agricultural polyolefin films, effectively eliminates fog inside greenhouses and improves light transmittance; reduces electrostatic dust adsorption on film surce, prolonging film service life AgrochemicalsPesticide emulsifierIn pesticide emulsifiable concentrate (EC) formulations, it helps the active ingredient self-emulsify quickly upon dilution to form a stable oil-in-water emulsion, ensuring uniform spraying and efficacy Coatings & InksPigment wetting and dispersing agentImproves wetting and dispersion stability of pigments and fillers, preventing pigment agglomeration, floating, flooding, and other defects, ensuring uniform film color and enhancing coating gloss Application Recommendations In actual formulation design, the HLB value of Span S-60 is approximately 4.7, making it suitable for use alone in W/O emulsification systems. If O/W emulsions or systems with broader HLB values are required, it is recommended to be used in combination with Tween series (e.g., Tween-60, Tween-80). By adjusting the ratio of the two, the overall HLB value can be precisely controlled. The generally recommended dosage is 0.5% to 5% of the total formulation, and the specific dosage should be determined experimentally based on the oil phase ratio of the emulsification system and the desired product characteristics. Before use, please note that the product may solidify at low temperatures, which is a normal physical change. It can be used normally after returning to room temperature and appropriate stirring. In food-grade applications, ensure that the product complies with the food additive regulations and standards of the corresponding country or region (e.g., GB 25552, FDA 21 CFR, etc.). Precautions It is recommended to wear chemical protective gloves and goggles during operation to avoid dust inhalation, and use in a well-ventilated area. Store in a cool, dry, and ventilated place, with a recommended temperature below 35°C, avoiding direct sunlight and contact with strong oxidizers. The product may cause mild skin and eye irritation (GHS category 2). In case of contact, rinse immediately with plenty of water. For specific safe handling, please refer to the Safety Data Sheet (SDS).

Question 10

What are the physicochemical technical parameters of Span S-60?

Accepted Answer

Complete List of Physicochemical Technical Parameters of Span S-60 (Sorbitan Monostearate) Detailed Description Span S-60 (Span 60) is a classic nonionic surctant produced by Haian Guoli Chemical Co., Ltd., with CAS number 1338-41-6, molecular formula C₂₄H₄₆O₆, and molecular weight 430.61. The product appears as a white to light yellow waxy solid, exhibiting excellent water-in-oil (W/O) emulsifying ability, with an HLB value of 4.7, making it a lipophilic emulsifier. It maintains stable performance over a wide pH range and under hard water conditions, and can be flexibly compounded with hydrophilic surctants such as Tween series to achieve precise design of emulsification systems. This product has high purity, with an active content ≥98%, solid content ≥99%, and monoester content ≥80%, all key indicators reaching industry-leading levels. It is soluble in hot oils and organic solvents, non-flammable under normal use conditions (flash point >149°C), and has an acute oral LD₅₀ > 15,000 mg/kg, classifying it as a low-toxicity substance. It is widely used in food, cosmetics, pharmaceuticals, and industrial fields. The following is a complete list of physicochemical technical parameters compiled from the Guoli Chemical product database. The data are authentic and reliable, serving as a reference for formulation design, quality control, and procurement selection. Physicochemical Technical Parameters Table Parameter Item Specification Value Remarks Chemical Name Sorbitan Monostearate Systematic name CAS Number 1338-41-6 Unique chemical substance identifier Molecular Formula C₂₄H₄₆O₆ — Molecular Weight 430.61 — Appearance White to light yellow waxy solid Solid at room temperature Ionic Type Nonionic Unaffected by hard water and electrolytes HLB Value 4.7 Lipophilic, suitable for W/O emulsification Active Content ≥98% High purity product Solid Content ≥99% — Melting Point 52~57°C Melting range of waxy solid Density Approx. 1.0 g/cm³ Approximate value Flash Point (Closed Cup) >149°C Non-flammable under normal use conditions Solubility Soluble in hot oils and organic solvents Insoluble in cold water pH Value (5% Aqueous Dispersion) 5.0~7.0 Nearly neutral Water Content ≤1.5% Low moisture content Acid Value ≤10 mg KOH/g Free tty acid control indicator Saponification Value 145~160 mg KOH/g Characterization of ester bond content Hydroxyl Value 230~270 mg KOH/g Characterization of hydroxyl content Iodine Value ≤2 g I₂/100g Very low unsaturation Monoester Content ≥80% Main active component Diester Content ≤20% — Free Alcohol ≤1% Residual sorbitol/sorbitan Heavy Metals (as Pb) ≤10 mg/kg Meets food grade requirements Arsenic (As) ≤3 mg/kg Meets food grade requirements Foaming Property <td

Span S-60 (Sorbitan Monostearate)

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Related Products

Property	Value
CAS No.	1338-41-6
Molecular Formula	C24H46O6
Appearance	White to pale yellow waxy solid
Ionic Type	Nonionic
Avg. Molecular Weight	430.61
Active Content	≥98%
pH Value(5%)	5.0~7.0
Iodine Value	≤2
Solubility	Soluble in hot oils and organic solvents
Acid Value	≤10
Saponification Value	145~160
Hydroxyl Value	230~270
Moisture	≤1.5
Density	~1.0
Flash Point	>149°C
Hygroscopicity	Low
Chemical Stability	Stable; avoid strong acids, strong alkalis and high temperature
Foam Property	Low foam
Alkali Resistance	Fair; hydrolyzes under strong alkali
Unsaturation	Extremely low
Viscosity	Solid, N/A
Melting Point	52~57
Monoester Content	≥80%
Diester Content	≤20%
Solid Content	≥99%
Free Alcohol	≤1%
Heavy Metal	≤10 mg/kg
Arsenic	≤3 mg/kg

Span S-60 (Sorbitan Monostearate)

Product Details

Applications

Properties

Safety

Product Overview

Performance Features

Packaging and Storage

Span / Sorbitan Ester Applications

Product Properties

Safety

GHS

Handling

Storage

First Aid

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