Question 1

Is Span S-20 lauric acid harmful to humans? Does it have an impact on the environment?

Accepted Answer

Under standard operating conditions, Span S-20 lauric acid is a low-toxicity and low-irritation substance to humans, but protection is still required; its overall impact on the environment is relatively small, but it should not be discharged directly into water bodies. Detailed Explanation Span S-20 (sorbitan monolaurate) is a nonionic surctant refined through esterification. From a toxicological perspective, this product is classified as low-toxicity and is used in the food, pharmaceutical, and cosmetic industries, meeting relevant excipient standards, indicating that its safety is recognized under limited usage conditions. However, this does not mean that its potential health risks can be ignored. This product is classified as an irritant (Xi), irritating to skin, eyes, and respiratory system (R36\/37\/38). Short-term exposure may cause local redness and discomfort; prolonged or repeated exposure may also cause skin detting and dryness. Therefore, during actual operations, wearing chemical safety goggles, nitrile or neoprene gloves, and long-sleeved work clothes is necessary protective measures. In case of accidental eye contact, immediately flush with plenty of water for at least 15 minutes and seek medical attention. Regarding environmental impact, the molecular structure of Span S-20 is based on natural tty acids (lauric acid) and sorbitan, providing good biodegradability and low persistence in the environment. However, as a surctant, if a large amount leaks into water bodies, it may still have adverse effects on aquatic organisms by reducing surce tension. Therefore, spills should be collected using inert absorbent materials and not be discharged into sewers or water bodies; waste should be disposed of in compliance with local regulations as non-hazardous industrial waste. Technical Parameters ParameterDescription Chemical NameSorbitan monolaurate CAS Number1338-39-2 Product TypeNonionic surctant Hazard SymbolXi (Irritant) R PhrasesR36\/37\/38 — Irritating to eyes, respiratory system, and skin BiodegradabilityGood biodegradability (no specific degradation rate data available at present) Dangerous Goods ClassificationNot classified as dangerous goods under current regulations Storage TemperatureRecommended 5°C to 35°C Storage PeriodShould not exceed 24 months from date of manucture Application Recommendations Given the low toxicity of Span S-20, it is widely used in the food industry (baking ts, powdered cream, chocolate coatings), pharmaceutical preparations (topical creams, ointment bases), and cosmetics (creams, lotions). In compounding formulations, the recommended dosage should be determined based on specific process requirements. When used as a W\/O emulsifier, it is typically combined with hydrophilic emulsifiers (such as Tween series), and optimal emulsification can be achieved by adjusting the HLB value. Precautions Personal Protection: Always wear protective goggles, chemical-resistant gloves, and work clothes during operation, and maintain good ventilation in the work area. Skin Contact Treatment: Immediately remove contaminated clothing and rinse with plenty of running water and soap for at least 15 minutes; seek medical attention if irritation persists. Eye Contact Treatment: Immediately open eyelids and flush thoroughly with plenty of water or normal saline for at least 15 minutes; seek medical attention as soon as possible. Environmental Protection: Do not discharge the product directly into sewers, surce water, or groundwater. In case of spillage, absorb with inert materials such as vermiculite or dry sand, seal, and dispose of in compliance with regulations. Combustion Products: During a fire, combustion may produce carbon monoxide, carbon dioxide, and trace irritant vapors; firefighters must wear self-contained breathing apparatus. Special Populations: Pregnant or breastfeeding women and individuals with a history of skin allergies should avoid direct contact.

Question 2

What should I do if there is a problem during the use of Span S-20 lauric acid? How can I obtain technical support?

Accepted Answer

If problems occur during the use of Span S-20 lauric acid, it is recommended to first conduct targeted troubleshooting based on the specific phenomenon. If the issue cannot be resolved, you can directly contact the technical team of Guoli Chemical for professional support. Common usage issues and troubleshooting methods Span S-20 (CAS No.: 1338-39-2) is a water-in-oil nonionic emulsifier with an HLB value of approximately 8.6. Common issues during use can be self-checked according to the following directions: 1. Poor emulsification effect, emulsion stratification or instability This is the most common problem. Possible causes include: ① HLB value mismatch - Span S-20 has strong lipophilicity. If used alone in an oil-in-water system, it needs to be compounded with high HLB hydrophilic emulsifiers (such as Tween series) to adjust to the required HLB value of the target oil phase; ② Insufficient dosage - It is recommended to start from 2% to 5% of the weight of the oil phase and gradually optimize; ③ Improper process - Excessive temperature difference between the oil phase and water phase or insufficient homogenization speed can affect the emulsification effect. It is recommended to heat both the oil phase and water phase to 40-50°C before mixing, and use a homogenizer for thorough shearing emulsification. 2. Product stratification, discoloration or precipitation First, check whether the storage conditions meet requirements. The recommended storage temperature for Span S-20 is 5°C to 35°C. Solidification or crystallization may occur below the melting point, which is a physical change and does not affect product quality. It can be restored by warming to room temperature and stirring evenly. If the product color significantly darkens or irreversible precipitation occurs, it may be due to storage temperature exceeding 35°C or exceeding the 24-month shelf life. A new batch should be replaced. 3. Turbidity, gel formation or incompatibility with other components in the formulation Span S-20 is nonionic and has good compatibility with anionic, cationic and nonionic surctants, but caution is needed in strong acid, strong alkali or systems containing high concentrations of electrolytes. It is recommended to check the pH of the system (suitable range 5~7) and avoid simultaneous use with strong oxidizers. If the formulation contains multiple surctants or additives, it is advisable to conduct small-scale compounding tests first, using the surce area incremental method to test compatibility. Quick reference of technical parameters ParameterValue AppearanceAmber to light yellow viscous liquid or waxy solid HLB valueApproximately 8.6 Active content≥99% pH of 1% aqueous solution5.0-7.0 Acid value (mgKOH\/g)≤7.0 Saponification value (mgKOH\/g)155~170 Hydroxyl value (mgKOH\/g)330~360 Critical micelle concentration CMCApproximately 2.5×10⁻⁵ mol\/L Kinematic viscosity (mPa·s)Approximately 4000-6000 Flash point (°C)＞150 Application recommendations For different industries using Span S-20, the following dosage ranges are recommended: Cosmetic creams\/lotions: 0.5%~5% (as primary W\/O emulsifier or auxiliary emulsifier in combination) Pesticide emulsifiable concentrates\/emulsions in water: 3%~10% (used in combination with hydrophilic emulsifiers, common compounding ratio is Span:Tween = 1:1 to 1:3) Food emulsification: Use according to the limits specified in GB 2760, referring to specific food categories Dispersion in paints and inks: 0.5%~2% of the pigment amount Metalworking fluids: 5%~15% (compounded with base oil and other additives) How to obtain technical support from Guoli Chemical Hai'an County Guoli Chemical Co., Ltd. provides professional technical application support services to every customer. You can contact us through the following methods: It is recommended to prepare the following information before contacting us, so that technical engineers can locate the problem ster: Product batch number (located on the packaging drum label) Usage formulation and process conditions (oil phase type, water phase ratio, addition order, temperature, homogenization method, etc.) Detailed description of the specific problem phenomenon (e.g., stratification, precipitation, discoloration, irritant odor), preferably with photos or samples Storage conditions and time since opening The Guoli Chemical technical team will provide professional solutions from the perspectives of formulation design, process optimization, product quality review, etc., based on the information you provide. If on-site technical guidance or sample re-inspection is required, we can also arrange technical services. Emergency safety situation handling If personnel safety is involved (e.g., eye splash, extensive skin contact, ingestion), immediately follow the emergency response measures in the product Safety Data Sheet and seek medical attention as soon as possible. Do not delay first aid while waiting for technical support. → Skin contact: Immediately remove contaminated clothing and rinse with plenty of running water and soap for at least 15 minutes. If irritation persists, seek medical attention. → Eye contact: Immediately open eyelids and rinse thoroughly with plenty of water or saline for at least 15 minutes, and seek medical attention as soon as possible. → Ingestion: Rinse mouth thoroughly with water, do not induce vomiting. Drink 1-2 glasses of water to dilute, seek medical attention immediately and show the product label.

Question 3

How to purchase Span S-20 laurate? What is the minimum order quantity?

Accepted Answer

For Span S-20 laurate, please contact the Guoli Chemical sales team for the latest quotation. There is currently no fixed minimum order quantity; standard packaging is 50kg/200kg plastic drums. Detailed Description Span S-20 laurate (CAS No.: 1338-39-2) is one of the core products of Hai'an Guoli Chemical Co., Ltd. Its scientific name is sorbitan monolaurate, a nonionic surctant with an HLB value of approximately 8.6. As an efficient water-in-oil (W/O) emulsifier, this product is widely used in multiple industrial fields such as cosmetics, food, pharmaceuticals, pesticides, textiles, and coatings. Due to the significant influence of upstream raw material market conditions, purchase quantity, and transportation distance on chemical raw material prices, the price information in the database is for reference only. The actual transaction price must be confirmed with the sales team in real-time. Guoli Chemical is a scaled manucturer with stable supply and sufficient inventory. The product's standard packaging includes 50kg and 200kg plastic drums, and the packaging material ensures the safety and stability of the product during transportation and storage. Whether for small trial samples or large-scale procurement, flexible coordination can be made according to customer needs. It is recommended that you contact the Guoli Chemical sales department directly, providing your region, estimated annual usage, and application direction. The sales engineer will provide you with an accurate quotation and customized service plan. Packaging and Logistics Information Item Details Standard Packaging 50kg/200kg plastic drums Packaging Material High-density polyethylene (HDPE) drums or lined coated iron drums Supply Lead Time Spot supply; specific delivery time depends on order quantity and shipping method Shipping Method Available by land or sea; supports self-pickup and logistics delivery Preparation Suggestions for Procurement To quickly obtain an accurate quotation and sample support, it is recommended that you prepare the following information before communicating with the sales team: Application Description: Specify the field in which the product will be used (e.g., cosmetic emulsification, pesticide formulation, food processing, etc.) so that technical personnel can confirm the suitability of the corresponding specification. Estimated Usage: Provide the annual usage or the budget for a single purchase to help secure more competitive tiered pricing. Delivery Address: Used to calculate the most economical logistics plan and freight costs. Sample Request: If testing is needed beforehand, free samples can be requested for small-scale trial verification. Precautions During storage, keep the container tightly closed and store in a cool, dry, and well-ventilated warehouse. The storage temperature is recommended to be controlled between 5°C and 35°C, avoiding freezing or continuous high temperatures. The product has a shelf life of 24 months (from the production date). Please plan inventory turnover cycles reasonably for large-scale purchases. When handling, follow the requirements of the Safety Data Sheet (SDS), and wear personal protective equipment such as impermeable gloves and safety goggles to avoid direct contact with skin and eyes.

Question 4

Is Span S-20 lauric acid environmentally compliant? Can a test report be provided?

Accepted Answer

Span S-20 lauric acid has good basic environmental characteristics, but specific environmental compliance needs to be assessed based on the application field and local regulations; according to the current product database, there is no directly available special environmental test report. Detailed Description Span S-20 lauric acid (sorbitan monolaurate), as a non-ionic surctant derived from the esterification reaction of natural tty acid (lauric acid) with sorbitan anhydride, has high biocompatibility in its chemical structure. According to the product database information, the product does not belong to dangerous goods as defined by current regulations, and the spill disposal guidelines clearly state that its waste "can be disposed of as non-hazardous industrial waste in accordance with local regulations", which reflects its basic environmental attributes from a regulatory classification perspective. From the perspective of core environmental indicators, Span S-20 lauric acid has low toxicity and low irritation safety characteristics, which provides a basis for its access to application fields with high environmental and safety requirements such as food, medicine, and cosmetics. However, the database currently does not include detailed ecotoxicological data of the product (such as acute aquatic toxicity LC50/EC50, biodegradability, etc.), so a comprehensive environmental compliance conclusion cannot be given. Actual environmental compliance (such as EU REACH regulations, China's new chemical substance environmental management measures, etc.) needs to be determined by professional institutions based on specific usage scenarios and local regulatory requirements. About Test Reports Currently, the Guoli Chemical product database has not included a special environmental test report for Span S-20 lauric acid (such as biodegradability test report, ROHS test report, REACH-SVHC test report, or VOC content report, etc.). The technical parameters provided in the product database mainly focus on physical and chemical indicators and application performance. To obtain complete environmental compliance documents or third-party test reports, it is recommended to directly contact the sales or technical department of Hai'an Guoli Chemical Co., Ltd. through official channels to request the latest product analysis certificate (COA), material safety data sheet (MSDS), and test reports for specific items. Application Suggestions If you need to evaluate its environmental compliance in specific applications, it is recommended to start from the following aspects: Cosmetics/Food-grade applications: Need to confirm whether the product meets the excipient standards of regulations such as China's "Cosmetic Safety Technical Specifications", EU EC 1223/2009, or US FDA 21 CFR, and request the purity and impurity test reports for the corresponding batch. Industrial cleaning/Textile auxiliaries applications: It is recommended to pay attention to the primary biodegradability data of the product and ensure that the wastewater treatment system has sufficient removal capacity for non-ionic surctants. Export compliance: If the product is for export, it is necessary to require the ctory to provide corresponding compliance declarations or test reports according to destination regulations (such as EU REACH registration or US TSCA inventory status). Precautions During operation, follow the product safety instructions. Spilled material should be collected using inert absorbent materials and disposed of according to local regulations. **Strictly prohibited from directly discharging into sewers or water bodies** to prevent potential impact on the environment.

Question 5

What are the advantages of Span S-20 lauric acid compared to other similar products?

Accepted Answer

The core advantages of Span S-20 lauric acid lie in its precise lipophilic properties, excellent formulation compatibility, and broad application safety Detailed Explanation As a classic nonionic surctant, the advantages of Guoli Chemical's Span S-20 (Span 20) are first reflected in its precise lipophilic positioning. Compared with other products in the Span series (such as Span-60 and Span-80), its HLB value is approximately 8.6, making it one of the "gold standards" among water-in-oil (W/O) emulsifiers. Its longer carbon chain structure (based on lauric acid) endows it with stronger lipophilicity and lower intercial tension, enabling it to more efficiently emulsify light mineral oils, esters, and silicone oils, thereby producing finer and more stable emulsions—an effect that products with lower HLB values find difficult to achieve directly. Secondly, Span S-20 demonstrates unparalleled chemical compatibility and formulation flexibility. As a nonionic surctant, it can be stably compounded with anionic, cationic, and amphoteric surctants over a wide pH range (weak acid to neutral), without the common mutual interference or precipitation issues associated with ionic surctants. This "versatile supporting role" characteristic allows formulators to freely combine it, for example, with Tween series to precisely adjust the HLB value of the system, enabling flexible transformation between W/O and O/W emulsion types, greatly expanding its application boundaries in complex formulation systems. Finally, its comprehensive safety and multi-scenario applicability are another major competitive advantage. Based on information from the Guoli Chemical database, Span S-20 is a low-toxicity, low-irritation product that meets strict excipient standards in the food, pharmaceutical, and cosmetics fields. Compared with some similar synthetic A/O (alkylphenol ethoxylate) emulsifiers, Span S-20 has no environmental hormone controversy, has better biodegradability, and meets the modern industry's demand for green, sustainable auxiliaries. This ability to combine high-efficiency emulsification performance with high safety makes it one of the preferred excipients in high-end personal care products, pharmaceutical preparations, and the food industry. Technical Parameters The following data, sourced from the Guoli Chemical product database, demonstrate the key performance indicators of Span S-20: Parameter ItemTypical Value of Guoli Chemical Span S-20Performance Comparison Advantage over Similar Products Chemical NameSorbitan MonolaurateA clear monoester structure (monoester content ≥95%) ensures high batch-to-batch consistency. HLB ValueApproximately 8.6Precisely positioned in the water-in-oil (W/O) emulsification region, offering high efficiency in emulsifying light oils. Ion TypeNonionicProvides excellent compounding compatibility, adapting to complex systems containing acids, bases, and salts. AppearanceAmber to pale yellow viscous liquidStandard appearance characteristics cilitate rapid quality identification upon receipt of raw materials. Saponification Value155 ~ 170 mgKOH/gReflects a suitable tty acid chain length, ensuring good lipophilic group efficacy. Hydroxyl Value330 ~ 360 mgKOH/gHigh hydroxyl value provides potential sites for further chemical modification, such as esterification and etherification. Acid Value≤ 7.0 mgKOH/gLow acid value ensures minimal interference with the pH of the formulation system, reducing potential impact on sensitive ingredients. Moisture Content≤ 1.5%Very low moisture content effectively inhibits bacterial growth and raw material hydrolysis in formulations requiring anhydrous environments. Critical Micelle Concentration (CMC)Approximately 2.5×10⁻⁵ mol/LLow CMC value means emulsification and solubilization effects can be achieved at very low concentrations, offering high economic efficiency. Surce TensionApproximately 28 mN/mSignificantly reduces oil/water intercial tension, providing a thermodynamic basis for forming stable emulsions. Application Recommendations Based on the above advantages, Span S-20 is particularly indispensable in the following scenarios: High-end Creams and Emulsion Systems: Utilizing its precise W/O emulsification capability and fine skin feel, it can be used to prepare cial creams and sunscreens with a refreshing texture and good nutrient encapsulation. It is recommended to be compounded with Tween-20 or Tween-80 to adjust the HLB value to 6-9, with a total emulsifier dosage commonly at 3%-5%. Mild Pharmaceutical Ointments for Active Ingredients: Its nonionic nature and high purity ensure no interference with active pharmaceutical ingredients (APIs), making it suitable for preparing ointment bases for hormones and antifungals, ensuring effective drug release and skin tolerance. Pesticide Emulsifiable Concentrates (EC) Requiring High Stability: Used as an emulsifying monomer, compounded with anionic emulsifiers (such as calcium dodecylbenzenesulfonate), it significantly improves the automatic dispersibility and emulsion stability of pesticide ECs in hard water, reducing the risk of phytotoxicity. Precautions When using Span S-20, please note: Dissolution Method: This product is soluble in oils and organic solvents but only dispersible in water. During preparation, first mix and heat it with the oil phase components to dissolve, then mix with the homogenized (or heated) water phase for emulsification to achieve the best results. Storage Conditions: Store in a cool, dry place at 5°C to 35°C, away from heat and open flames. Low temperatures may cause turbidity or solidification, which is normal. Warm to room temperature and stir evenly before use to restore efficacy. Safe Handling: The product is potentially irritating to skin and eyes (Xi). Wear nitrile gloves and chemical safety goggles during operation, ensure good ventilation, and avoid inhaling aerosols. Regulatory Status: This product from Guoli Chemical complies with food and pharmaceutical excipient standards. However, before use in end products, compliance verification should be conducted according to the target market.

Question 6

How should Span S-20 lauric acid be stored? What is its shelf life?

Accepted Answer

Span S-20 lauric acid should be stored in a cool, dry, and well-ventilated place. Its shelf life is 24 months from the date of manucture (refer to the product Certificate of Analysis for specific details). Detailed Description Span S-20 lauric acid (sorbitan monolaurate) is a nonionic surctant. Proper storage is crucial for maintaining its emulsifying properties and performance. The product should always be kept in a dedicated warehouse that is cool, dry, and well-ventilated, away from heat sources, sparks, and open flames to prevent deterioration or safety hazards. This product is flammable but not explosive. Under normal storage conditions, it is chemically stable. However, care should be taken to avoid storing it together with incompatible substances such as strong oxidizers, strong acids, and strong bases to prevent adverse reactions. If long-term storage is required, it is recommended to record the receiving date upon arrival and follow the "first in, first out" inventory management principle to ensure the product is used within its optimal period. Storage Parameters at a Glance Storage RequirementSpecific Description Temperature Range5°C to 35°C, avoid freezing or continuous high temperature Environmental ConditionsCool, dry, well-ventilated Container SealingReseal immediately after use to prevent vapor buildup and contamination Recommended Packaging MaterialsStainless steel, polyethylene, or lined iron drums, avoid copper and its alloys Incompatible SubstancesStrong oxidizers, strong acids, strong bases Shelf LifeNot exceeding 24 months from the date of manucture (refer to the product Certificate of Analysis) Other RequirementsPlace on corrosion-resistant trays to prevent spill spread; regularly check container sealing Storage Operation Recommendations During routine operations, personnel should pay attention to the following: Reseal the container immediately after product withdrawal to avoid prolonged exposure that could lead to contamination or moisture absorption, affecting the product's emulsifying properties. For liquid transfer, use closed piping or take grounding measures to prevent static accumulation. Containers should always be placed on corrosion-resistant trays to effectively contain accidental spills and prevent spreading to the floor and drainage system. If the product becomes cloudy or appears layered after storage at low temperatures, this is a normal physical phenomenon. It is recommended to slowly bring the product back to room temperature (15°C~25°C) before use and appropriately stir or recirculate it to restore uniformity, without affecting its emulsifying properties. Notes Products beyond their shelf life may have reduced emulsifying properties and chemical stability; it is recommended to conduct a small-scale test to verify effectiveness before use. Avoid using containers or tools made of copper or its alloys in contact with the product to prevent catalytic degradation. No eating, drinking, or smoking in the work area; thoroughly wash hands and exposed skin after operation and before breaks. In case of spillage, use inert absorbent materials (e.g., vermiculite, dry sand, diatomaceous earth) to contain and collect, and dispose of as non-hazardous industrial waste according to local regulations. Do not discharge into sewers or water bodies.

Question 7

What safety precautions should be taken when using Span S-20 lauric acid?

Accepted Answer

When using Span S-20 lauric acid, it is necessary to pay attention to its irritation risk. During operation, personal protection, standardized storage, and emergency preparedness must be ensured. Detailed Explanation Span S-20 lauric acid (sorbitan monolaurate) is classified as a Xi irritant chemical. Its hazard symbol is Xi (irritant), and the R phrases are R36/37/38, indicating irritation to eyes, respiratory system, and skin. Although this product is not classified as dangerous goods under current regulations, it must still be managed strictly in accordance with chemical specifications during industrial operations. Prolonged or repeated contact may also cause skin detting and mild irritation, so it should not be taken lightly. During operation, ensure good ventilation in the workplace, and install local exhaust ventilation if necessary. For personal protection, chemical safety goggles, nitrile rubber or neoprene gloves, and long-sleeved work clothes must be worn. When there is a risk of splashing or exposure to high concentrations of vapor, a combination filter mask for particulates/organic gases should also be worn. Eating, drinking, and smoking are strictly prohibited in the workplace. Wash hands and exposed skin thoroughly after handling and before breaks. Containers should be resealed immediately after use to prevent vapor accumulation and impurity intrusion. Pregnant and lactating women, as well as individuals with a history of skin allergies, should avoid direct contact. For storage, keep the product in a cool, dry, well-ventilated dedicated warehouse, away from heat sources, sparks, and open flames. The storage temperature is recommended to be between 5°C and 35°C, avoiding freezing or prolonged high temperatures that may affect the product's emulsifying properties. Packaging materials should preferably be stainless steel, polyethylene, or lined iron drums. Avoid using copper and its alloys. The product should not be stored for more than 24 months from the date of manucture. Summary of Key Safety Operation Points Risk CategorySpecific HazardProtective Measures Eye ContactIrritant, R36Wear chemical safety goggles; in case of accidental contact, immediately flush with plenty of water for at least 15 minutes and seek medical attention Respiratory SystemIrritant, R37Ensure adequate ventilation; if necessary, wear a combination filter mask for particulates/organic gases Skin ContactIrritant, R38; prolonged contact may cause dettingWear nitrile rubber or neoprene gloves and long-sleeved work clothes IngestionGastrointestinal irritationRinse mouth with water immediately; do not induce vomiting; drink 1-2 glasses of water to dilute; seek medical attention immediately FireCombustible but not explosiveUse dry powder, carbon dioxide, water fog, or alcohol-resistant foam for extinguishing; do not use a direct water jet Emergency Response Guidelines Skin Contact: Immediately remove contaminated clothing and wash with plenty of running water and soap for at least 15 minutes. If irritation persists or redness occurs, seek medical attention. Eye Contact: Immediately hold eyelids open and rinse thoroughly with plenty of water or saline solution for at least 15 minutes. During rinsing, move the eyes in all directions to ensure thorough cleaning of the conjunctival fornix. Seek medical attention as soon as possible and present this safety information (S26). Inhalation: Move the affected person to fresh air immediately, keep the airway clear, and keep warm and at rest. If breathing is difficult, administer oxygen immediately; if breathing stops, trained personnel should perform artificial respiration and seek medical attention immediately. Spill Disposal: Evacuate unauthorized personnel. After operators put on protective equipment, cut off the leak source. Use inert absorbent materials (such as vermiculite, dry sand, diatomaceous earth) to contain and collect the spilled liquid. Place waste in sealed containers and dispose of in accordance with local regulations. Avoid discharge into sewers or waterways. Precautions Ensure that the product is not stored together with incompatible materials such as strong oxidizers, strong acids, and strong bases. When transferring liquids, use closed piping or take grounding measures to prevent static accumulation. In case of fire, combustion may produce carbon monoxide, carbon dioxide, and trace amounts of irritating vapors. Firefighters must wear self-contained breathing apparatus and full protective clothing. For more detailed information, be sure to refer to the product's Safety Data Sheet (SDS).

Question 8

How to use Span S-20 laurate? What is the recommended addition amount?

Accepted Answer

Usage and Recommended Addition Amount of Span S-20 Laurate Detailed Description Span S-20 laurate (Span 20) is a nonionic water-in-oil (W/O) emulsifier with an HLB value of approximately 8.6. It is typically used via the oil-phase pre-dissolution method. In practice, it should be added to the oil phase component, heated to 40–60°C, and stirred until fully dissolved. Then, the water phase is slowly added to the oil phase under high-speed homogenization to form a stable W/O emulsion system. If used for O/W emulsions (requiring combination with high-HLB emulsifiers), it is recommended to pair it with Tween series (e.g., Tween-20, Tween-80) to achieve the desired hydrophilic-lipophilic balance. Span S-20 laurate is a viscous liquid or waxy solid at room temperature. If solidification or crystallization occurs at low temperatures, it is recommended to preheat and melt it in a 20–35°C water bath. Do NOT use open flames or excessive heat (temperatures above 80°C may cause ester bond cleavage and affect emulsification performance). Stir thoroughly before feeding to ensure accurate and consistent addition amounts per batch. This product has good compatibility with anionic, cationic, and other nonionic surctants, allowing flexible compounding in complex formulations. Important Note on Recommended Addition Amount: The product database of Guoli Chemical does not include specific recommended addition amounts for this product in various application fields. The following are reference dosage ranges based on general industry practices for surctants and the HLB value (8.6) characteristics of this product. Actual dosage should be determined through experiments based on the formulation system. Technical Parameters Parameter ItemValue/Description Chemical NameSorbitan monolaurate Ionic TypeNonionic surctant HLB ValueApprox. 8.6 (Source: Guoli Chemical Product Database) AppearanceAmber to pale yellow viscous liquid or waxy solid Active Content≥99% Monoester Content≥95% Acid Value≤7.0 mgKOH/g Saponification Value155–170 mgKOH/g Hydroxyl Value330–360 mgKOH/g Moisture≤1.5% pH of 1% Aqueous Solution5.0–7.0 Flash Point>150℃ SolubilitySoluble in oils and organic solvents; dispersible in water forming an emulsion Application Recommendations Usage Method Overview: Add Span S-20 laurate to the oil phase according to the formulation amount, heat to 40–60°C with stirring to dissolve, then slowly add the water phase (or water phase containing hydrophilic emulsifiers) to the oil phase under high-speed homogenization. For O/W emulsions, combine with Tween series (HLB range typically 10–15). General Reference Addition Amounts by Field (Industry experience, not from Guoli Chemical database): Cosmetic Creams/Lotions: As a W/O emulsifier, recommended addition amount is 1%–5% of the total formulation. When combined with Tween, the ratio of Span to Tween is usually 1:1 to 1:3. Food Bakery ts/Non-dairy Creamer: Addition amount is generally 0.3%–1.0% of the total oil content, subject to GB 2760 food additive usage standards. Pharmaceutical Creams/Ointment Bases: Recommended addition amount is 2%–8% of the base total, used in combination with cetyl alcohol, petrolatum, etc. Pesticide Emulsifiable Concentrates/Emulsions in Water: As an emulsifier monomer, addition amount is usually 3%–10% of the total formulation, requiring combination with hydrophilic emulsifiers. Textile Softeners/Antistatic Agents: Addition amount is 0.5%–3% of the working solution total. Paint/Ink Pigment Dispersion: Recommended dosage is 1%–5% of the pigment amount, requiring pre-grinding dispersion. Metalworking Fluids: As an emulsifier component, addition amount is 5%–15% of the concentrate total. Precautions This product is irritating to skin, eyes, and respiratory tract (Hazard symbol: Xi). Nitrile rubber gloves, chemical safety goggles, and long-sleeved work clothes must be worn during operation. If combining with Tween series emulsifiers, calculate the required HLB value based on the oil phase characteristics of the target emulsion, then determine the compounding ratio of Span to Tween. Emulsification temperature should not exceed 80°C to avoid ester bond hydrolysis, which may reduce product performance. The pH of a 5% aqueous solution is 5.0–7.0; the product is stable in weakly acidic to neutral media. Under strongly alkaline conditions, slow saponification may occur. Storage temperature is recommended at 5°C–35°C, away from strong oxidizers, strong acids, and strong bases, and avoid using copper containers. Shelf life should not exceed 24 months from the production date, subject to the product analysis certificate. The above reference addition amounts are industry general experience ranges. The actual formulation dosage should be determined through small-scale experiments to identify the optimal addition ratio.

Question 9

What are the main industries and processes where Span S-20 (Sorbitan monolaurate) is primarily used?

Accepted Answer

Span S-20 (Sorbitan monolaurate) is a multifunctional nonionic W/O emulsifier, widely used in seven major industries including cosmetics, food, pharmaceuticals, textiles, pesticides, coatings & inks, and metalworking, playing a core role in processes such as emulsification, dispersion, and solubilization. Detailed Description Span S-20 (Sorbitan monolaurate, CAS No.: 1338-39-2) is a nonionic surctant refined through esterification of lauric acid and sorbitan. It appears as a light yellow to amber viscous liquid with an HLB value of approximately 8.6. Its molecular structure contains a lipophilic long-chain lauric acid and hydrophilic sorbitan hydroxyl groups, giving it typical water-in-oil (W/O) emulsifying properties. It forms a stable intercial film at the oil-water interce, making it a key functional additive for preparing fine and stable emulsion systems. Due to its nonionic nature, Span S-20 has good compounding compatibility with anionic, cationic, and amphoteric surctants, maintaining stable activity in acidic, alkaline, and hard water media. It also offers safety advantages of low toxicity and low irritation, enabling its wide application in fields with stringent safety requirements such as food, pharmaceuticals, and cosmetics. Additionally, this product possesses multiple auxiliary functions such as wetting, dispersion, solubilization, and lubrication, making it a versatile platform-type industrial additive. At the application process level, the core roles of Span S-20 are mainly reflected in: as a primary or auxiliary emulsifier in the formulation of emulsions, creams, and emulsifiable concentrates; as a dispersant in coatings, inks, and pesticides to prevent aggregation and sedimentation of solid particles; as an emulsifying and dispersing carrier for softeners and antistatic agents in textile finishing; and providing synergistic emulsification and lubrication effects in metalworking fluids. Overview of Major Application Industries and Processes Industry Typical Products/Processes Core Functions Process Role Cosmetics & Personal Care Creams, lotions, sunscreens, makeup bases, cial cleansers W/O emulsification, thickening, imparting fine skin feel Primary or auxiliary emulsifier Food Industry Baking ts, non-dairy creamer, chocolate coatings, whipped cream, beverage emulsions Promoting uniform oil-water mixing, preventing separation, improving melt-in-mouth properties Food-grade emulsifier Pharmaceutical Preparations Topical creams, ointments, suppository bases Emulsification and solubilization, improving drug dispersion uniformity and transdermal absorption efficiency Pharmaceutical excipient emulsifying component Textile Auxiliaries Softening agents, antistatic agents Helping stable dispersion of silicone oil/wax substances in aqueous phase Emulsifying dispersing component Pesticide Formulations Emulsifiable concentrates (EC), emulsion concentrates (EW) Ensuring uniform dispersion and dilution stability of pesticide active ingredients Emulsifier monomer (often compounded with hydrophilic surctants) Paints & Inks Solvent-based and water-based coatings, printing inks Pigment dispersion, wetting, preventing particle aggregation and sedimentation Pigment dispersant and wetting agent Metalworking Fluids Cutting fluids, grinding fluids, rust preventive oils Promoting emulsification and dispersion of base oils, forming protective films, reducing friction and corrosion Synergistic emulsification and lubrication component Application Recommendations Compounding Strategy: Span S-20 has an HLB value of approximately 8.6, making it suitable as a primary emulsifier for W/O emulsion systems. In practical formulations, it is often compounded with high-HLB hydrophilic surctants (such as Tween series) to adjust the HLB value of the system to the target range, achieving broader emulsification adaptability and more stable emulsion products. In pesticide emulsifiable concentrates and emulsion concentrates, it is recommended to compound with hydrophilic emulsifiers in a certain ratio to spontaneously form a stable emulsion upon dilution. Dosage Reference: The specific dosage should be determined experimentally according to the formulation system and process requirements. Typically, the usage amount is 1%-5% in cosmetic creams, 3%-10% as an emulsifier monomer in pesticide emulsifiable concentrates, and 2%-8% in metalworking fluids. It is recommended to optimize the dosage through orthogonal experiments or response surce methodology. Process Temperature: This product maintains emulsifying activity over a wide process temperature range, but storage temperature is recommended to be controlled between 5°C and 35°C, avoiding freezing or sustained high temperatures to prevent affecting emulsification performance. During high-temperature operations (such as hot compounding processes), it is recommended to slowly add it to the oil phase under stirring for pre-dispersion. Precautions Safety Protection: This product is irritating to skin, eyes, and respiratory system (R36/37/38). Operators should wear chemical safety goggles, nitrile or neoprene gloves, and long-sleeved work clothes, and ensure adequate ventilation in the workplace. Emergency Treatment: In case of eye contact, immediately rinse with plenty of water for at least 15 minutes and seek medical attention; for skin contact, wash with soap and plenty of water. Storage Requirements: Store in a cool, dry, well-ventilated warehouse, away from heat sources and open flames. Keep containers tightly closed, and store separately from strong oxidizers, strong acids, and strong alkalis. Recommended storage period should not exceed 24 months from the date of manucture. Packaging Material: Use stainless steel, polyethylene, or lined iron drums; avoid containers made of copper or its alloys. Compounding Compatibility: Its nonionic nature gives it good compounding compatibility with various surctants, but when compounding with specific additives, it is recommended to conduct small-scale compatibility tests first.

Question 10

What are the physicochemical technical parameters of Span S-20 lauric acid?

Accepted Answer

Overview of Physicochemical Technical Parameters of Span S-20 Lauric Acid (Span 20) Detailed Description Span S-20 lauric acid (CAS No.: 1338-39-2), with the chemical name sorbitan monolaurate, is a non-ionic surctant produced by Guoli Chemical. The product appears as an amber to light yellow viscous liquid or waxy solid, with a typical tty ester odor, and is an excellent water-in-oil emulsifier. The HLB value of this product is approximately 8.6, classifying it as a lipophilic emulsifier. It is soluble in oils and organic solvents and disperses in water to form an emulsion. Its surce tension is about 28 mN/m, with a critical micelle concentration (CMC) of approximately 2.5×10⁻⁵ mol/L, demonstrating good intercial activity. The product has excellent chemical stability, remaining stable under normal conditions and maintaining activity even in weak alkaline media. It is characterized by low foaming and low hygroscopicity. The product has an active content of no less than 99%, with monoester content ≥95%, diester content ≤5%, and free alcohol ≤2%, ensuring high purity. The molecular formula is C18H34O6, with a molecular weight of 346.46. All indicators meet the excipient standards required for high-end applications such as food, pharmaceuticals, and cosmetics. Technical Parameters Parameter ItemIndex Value Chemical NameSorbitan monolaurate (sorbitan monododecanoate) CAS Number1338-39-2 Molecular FormulaC18H34O6 Molecular Weight346.46 AppearanceAmber to light yellow viscous liquid or waxy solid Ionic TypeNon-ionic HLB Value8.6 Active Content≥99% Monoester Content≥95% Diester Content≤5% Free Alcohol≤2% Acid Value≤7.0 mgKOH/g Saponification Value155~170 mgKOH/g Hydroxyl Value330~360 mgKOH/g Iodine Value≤10 Moisture Content≤1.5% pH of 1% Aqueous Solution5.0~7.0 pH of 5% Aqueous Solution5.0~7.0 DensityApproximately 1.0~1.1 g/cm³ Kinematic Viscosity (Low Shear)Approximately 4000~6000 mPa·s Refractive IndexApproximately 1.47~1.48 Melting Point<10°C Flash Point>150°C Cloud PointApproximately 25°C Surce TensionApproximately 28 mN/m Critical Micelle Concentration (CMC)Approximately 2.5×10⁻⁵ mol/L Foaming PropertyLow foaming HygroscopicityLow hygroscopicity Chemical StabilityStable under normal conditions Alkali ResistanceStable in weak alkali Heavy Metals≤20 ppm Arsenic≤2 ppm SolubilitySoluble in oils and organic solvents; disperses in water to form an emulsion Packaging Specifications50kg / 200kg plastic drum Application Suggestions As a lipophilic emulsifier, Span S-20 lauric acid is typically used in combination with hydrophilic surctants (such as the Tween series) to achieve a wider HLB adjustment range and more stable emulsification effects. In cosmetic cream formulations, the recommended dosage is 1%~5%; in pesticide emulsifiable concentrate systems, it can be combined with hydrophilic emulsifiers to promote spontaneous emulsification; in food baking oils, the recommended dosage should comply with GB 2760 standards. When applied in pharmaceutical preparations and the food industry, it is necessary to confirm that the product meets the corresponding pharmacopoeia or food additive standard batches. The product has a monoester content ≥95%, and its high purity ensures superior performance in sensitive formulations. Precautions Irritancy: This product is irritating to the skin, eyes, and respiratory tract (Xi category). During handling, protective gloves, goggles, and protective clothing should be worn, and the work area should be well ventilated. Storage Temperature: It is recommended to store at 5°C~35°C, avoiding freezing or sustained high temperatures, which may affect the emulsifying performance of the product. Shelf Life: The storage period should not exceed 24 months from the date of production (refer to the product certificate of analysis for specific details). Avoid co-storage with strong oxidizers, strong acids, and strong alkalis. Packaging Selection:

Span S-20 Lauric Acid

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Property	Value
CAS No.	1338-39-2
Molecular Formula	C18H34O6
Appearance	Amber to pale yellow viscous liquid or waxy solid
Ionic Type	Nonionic
Avg. Molecular Weight	346.46
Cloud Point	~25°C
Active Content	≥99%
pH Value(1%)	5.0-7.0
pH Value(5%)	5.0-7.0
Iodine Value	≤10
Solubility	Soluble in oils and organic solvents; dispersible in water forming emulsion
Surface Tension	~28
CMC	~2.5×10⁻⁵ mol/L
Acid Value	≤7.0
Saponification Value	155~170
Hydroxyl Value	330~360
Moisture	≤1.5
Density	~1.0-1.1
Kinematic Viscosity	~4000-6000
Refractive Index	~1.47-1.48
Flash Point	>150
Hygroscopicity	Low hygroscopicity
Chemical Stability	Stable under normal conditions
Penetration	Low
Foam Property	Low foam
Alkali Resistance	Stable in weak alkali
Unsaturation	Low
Viscosity	~4000-6000
Melting Point	<10
Monoester Content	≥95%
Diester Content	≤5%
Low Shear Viscosity	~4000-6000 mPa·s
Solid Content	≥99%
Free Alcohol	≤2%
Heavy Metal	≤20
Arsenic	≤2

Span S-20 Lauric Acid

Product Details

Applications

Properties

Safety

Product Overview

Performance Features

Packaging and Storage

Span / Sorbitan Ester Applications

Product Properties

Safety

GHS

Handling

Storage

First Aid

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