Question

Is oleic acid polyoxyethylene ester A-105 (OEO-105) harmful to humans? Does it have an impact on the environment?

Answer
2026-06-06 官方文档 油酸聚氧乙烯酯A-105,OEO-105

Oleic acid polyoxyethylene ester A-105 (OEO-105) is a low-toxicity substance, with only slight irritation to skin and eyes. It is environmentally friendly, biodegradable, and safe for human health and ecological environment under normal use conditions.

Detailed Description

Oleic acid polyoxyethylene ester A-105 (OEO-105) is a nonionic surfactant derived from natural oleic acid. From a toxicological perspective, its acute oral LD50 is > 5000 mg/kg (rat), classifying it as a low-toxicity substance with low risk. Under normal industrial handling conditions, the main effects on humans are limited to slight skin and eye irritation. Prolonged or repeated contact may cause defatting and drying of the skin. Inhalation of high-temperature vapors or mists may cause respiratory discomfort, but such exposure is not common under routine operating conditions.

From an environmental fate perspective, A-105 has no significant toxicity to aquatic organisms, can gradually biodegrade in water, does not persist in the environment, and has no bioaccumulation potential. It should be noted that while small, single discharges have limited environmental impact, large spills that are directly discharged into water bodies without treatment may cause temporary effects on local aquatic ecosystems. Therefore, enterprises should establish emergency containment procedures for spills.

Comprehensive assessment: Under compliance with standard operating procedures and proper use of personal protective equipment (e.g., gloves, goggles), the overall risk of A-105 to human health and the ecological environment is low. It is an industrial surfactant that combines safety, environmental friendliness, and functionality.

Health and Environmental Impact Parameters

Assessment ItemData/ConclusionRisk Level
Acute oral toxicityLD50 > 5000 mg/kg (rat)Low toxicity
Skin irritationSlight irritationLow risk
Eye irritationSlight irritationLow risk
Inhalation riskHigh-temperature vapor/mist may cause discomfortNo significant risk under routine operations
Aquatic toxicityNo significant toxic effectsLow risk
BiodegradabilityBiodegradableEnvironmentally friendly
BioaccumulationNo bioaccumulation potentialEnvironmentally friendly
FlammabilityNot easily flammableSafe for storage and transport

Safe Handling Recommendations

  • Personal protection: Wear nitrile or chloroprene rubber gloves and splash-proof chemical goggles. Respiratory protection is generally not required; if large amounts of aerosol are generated, wear a filtering respirator.
  • Engineering controls: Maintain good ventilation or local exhaust in the work area to control airborne mist concentrations.
  • Storage conditions: Store in a cool, dry, well-ventilated area in a sealed container, at temperatures not exceeding 40°C, away from direct sunlight and separate from strong oxidizers.
  • Spill management: Collect using inert absorbent materials such as sand or vermiculite, prevent entry into drains or surface waters, and dispose of collected material as industrial waste in compliance with regulations.

Precautions

In case of skin contact, rinse immediately with plenty of running water and soap for at least 15 minutes. In case of eye contact, rinse continuously with water or saline for at least 15 minutes and seek medical attention immediately. If ingested, do not induce vomiting; rinse mouth and seek medical attention. Although the overall risk of this product is low, large spills still require emergency environmental containment to prevent impact on local water bodies.