L-62 Poloxamer (Poloxamer 182) is a nonionic block copolymer surfactant. From a toxicological perspective, its acute oral toxicity is extremely low (LD₅₀ rat > 5,000 mg\/kg), classified as "practically non-toxic" according to toxicological classification. Available scientific data indicates that this product does not have germ cell mutagenicity, carcinogenicity, or reproductive toxicity, and does not cause skin sensitization, and is not classified under these serious hazard categories according to the specified GHS hazard categories.
However, this product is not completely harmless. According to the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), L-62 Poloxamer is classified as Skin Irritant Category 2 (H315) and Serious Eye Damage\/Eye Irritant Category 2 (H319). This means that direct skin contact may cause mild discomfort, while eye contact can cause significant irritation, pain, tearing, and redness. Therefore, wearing protective goggles and gloves is a necessary safety measure during handling.
In terms of environmental safety, L-62 Poloxamer performs well: it has low toxicity to aquatic organisms and is not expected to cause short-term or long-term negative ecological impacts; it is readily biodegradable, meaning it does not persist in the environment after release; and it does not have significant bioaccumulation potential, so it does not magnify along the food chain. Overall, under the premise of complying with standard usage and disposal practices, this product poses a low risk to the ecological environment.
| Assessment Dimension | Result | Classification\/Description |
|---|---|---|
| Acute Oral Toxicity | LD₅₀ (rat) > 5,000 mg\/kg | Practically non-toxic |
| Skin Irritation | GHS Category 2 | H315: Causes skin irritation |
| Eye Damage\/Irritation | GHS Category 2 | H319: Causes serious eye irritation |
| Skin Sensitization | No sensitization | Available data indicates no skin allergy |
| Genotoxicity\/Carcinogenicity | No relevant evidence | Not classified as a hazard category |
| Aquatic Toxicity | Low toxicity | No adverse ecological effects expected |
| Biodegradability | Readily biodegradable | Does not persist in the environment |
| Bioaccumulation | Not significant | No risk of food chain magnification |
L-62 Poloxamer is widely used in industrial and institutional cleaning, metalworking fluids, agrochemicals, emulsion polymerization, and coatings and pigment dispersion. Its low toxicity and good environmental compatibility make it suitable for use in various industrial formulations. In scenarios such as automatic dishwasher rinse aids and hard surface cleaners, where indirect contact with food or human body may occur, its safety has been fully verified. At typical formulation dosages (usually 0.1% to 5%), it does not pose a health risk to end users.