Question

What is Polyethylene Glycol PEG-200

Answer
2026-05-27 官方文档 聚乙二醇PEG-200

Polyethylene Glycol PEG-200 (CAS No.: 25322-68-3) is a typical nonionic surfactant, appearing as a colorless transparent viscous liquid. With its excellent emulsifying, solubilizing, wetting, dispersing properties and chemical stability, it is widely used in daily chemicals, pharmaceuticals, industrial manufacturing, and chemical synthesis.

Detailed Description

Polyethylene Glycol 200 (PEG-200), chemically named α-hydro-ω-hydroxypoly(oxy-1,2-ethanediyl), is a high-quality nonionic surfactant produced by Guoli Chemical. This product is polymerized from ethylene oxide and water, with a molecular weight of approximately 200, and appears as a colorless transparent viscous liquid at room temperature.

PEG-200 possesses excellent chemical inertness and versatility. Its molecular structure contains ether bonds and terminal hydroxyl groups, giving it both hydrophilicity and certain lipophilicity, effectively reducing the interfacial tension between different liquid phases and promoting the stable dissolution and uniform mixing of poorly soluble substances. At the same time, this product is resistant to acids, alkalis, and hard water, and does not react with most chemicals over a wide range of operating conditions, ensuring the reliability of system performance.

As one of the core products of Guoli Chemical, PEG-200 has good compatibility with anionic, cationic, and other nonionic surfactants. It also has high toxicological safety—acute oral toxicity (rat) LD50 is greater than 2000 mg/kg, classified as low toxicity. It causes no or only very slight irritation to the skin, is readily biodegradable, and has no bioaccumulation potential, making it an environmentally friendly industrial auxiliary material choice.

Technical Parameters

Parameter ItemParameter Description
Chemical NamePolyethylene Glycol 200
CAS No.25322-68-3
AliasesPEG 200, Polyoxyethylene 200, PEG-200, Polyoxyethylene 200
Product TypeNonionic Surfactant
AppearanceColorless Transparent Viscous Liquid
Chemical Nameα-hydro-ω-hydroxypoly(oxy-1,2-ethanediyl)
Acute Oral Toxicity (Rat)LD50 > 2000 mg/kg (Low Toxicity)
Skin IrritationNo irritation or Very Slight Irritation (Skin Irritation Index 0 to 0.5)
Skin SensitizationNegative, No Sensitization
Genotoxicity (Ames Test)Negative, No Genotoxicity
BiodegradabilityReadily Biodegradable, No Bioaccumulation
Storage Temperature15°C to 30°C (Recommended)

Note: The database currently does not have specific physicochemical parameters such as hydroxyl value, density, viscosity, and HLB value for this product. For detailed specifications, please contact the technical department of Guoli Chemical.

Application Recommendations

Daily Chemical and Care Industry: As a humectant, lubricant, and viscosity modifier, it is widely used in shampoos, body washes, creams, and toothpaste formulations to impart a smooth skin feel. It is recommended to be used in combination with anionic or amphoteric surfactants to enhance the overall sensory experience of the product.

Pharmaceutical and Agricultural Industries: It serves as an ointment base, drug solubilizer, and pesticide emulsifying dispersant, effectively improving the bioavailability and efficacy of active ingredients. It can be used as a solubilizer in liquid formulations to improve the solubility of poorly soluble drugs.

Industrial Casting and Metalworking: Used as a key component of mold release agents and heat transfer fluids, providing excellent high-temperature lubricity and demolding performance. In the rubber and plastic industries, it acts as a base component of mold release agents, imparting excellent separation properties to mold surfaces.

Chemical Synthesis: As a solvent and synthesis intermediate, it participates in chemical reactions such as esterification and etherification, used to produce specialty surfactants, polyurethane resins, and plasticizers, providing flexible ethoxy chain segments.

Other Applications: As a dispersant and carrier in dye, pigment, and ceramic processing, improving particle dispersion uniformity; it can also serve as a base component for brake fluids and heat transfer fluids, providing suitable thermal conductivity and low-temperature fluidity.

Precautions

  • Safety goggles, protective gloves, and general work clothes should be worn during operation. Use in a well-ventilated area.
  • Avoid prolonged contact with eyes and skin. Thoroughly wash hands and exposed skin after operation.
  • Keep the container tightly sealed and store in a cool, dry, well-ventilated warehouse. Prevent moisture absorption. Keep away from incompatible substances such as strong acids and strong oxidizers.
  • It is recommended to use containers made of stainless steel, polyethylene, or carbon steel with an epoxy resin lining for storage.
  • If accidentally splashed into eyes, rinse immediately with plenty of water for at least 15 minutes. If irritation persists or vision is affected, seek medical attention immediately.
  • This product is not flammable and has no explosion hazard. However, combustion or thermal decomposition in a fire may produce irritating or toxic gases. Firefighters should wear self-contained positive pressure respirators.
  • Disposal must comply with national and local environmental regulations. Do not discharge into sewers, soil, or any water bodies.