Question

What is Polyethylene Glycol PEG-200?

Answer
2026-05-17 官方文档 聚乙二醇PEG-200

Polyethylene Glycol PEG-200 is a colorless, transparent, viscous liquid non-ionic surfactant with stable chemical properties, low toxicity, and mildness. It is widely used as a solubilizer, humectant, lubricant, and synthetic intermediate in pharmaceuticals, cosmetics, and industrial fields, among others.

Detailed Description

Polyethylene Glycol PEG-200 (CAS No.: 25322-68-3), chemical name α-Hydro-ω-hydroxypoly(oxy-1,2-ethanediyl), is a typical non-ionic surfactant produced by Guoli Chemical. Its molecular structure consists of ethoxy chains, appearing as a colorless, transparent, viscous liquid. With excellent chemical inertness and versatility, it is widely used as a high-performance auxiliary material and processing aid across various industrial fields.

PEG-200 possesses excellent emulsification and solubilization capabilities, effectively reducing interfacial tension between different liquid phases and promoting the stable dissolution and uniform mixing of poorly soluble substances. Additionally, it exhibits outstanding wetting and dispersing functions, significantly improving the wetting state of solid particles in liquid media, preventing sedimentation and flocculation, and enhancing formulation uniformity. In terms of chemical stability, PEG-200 demonstrates resistance to acids, alkalis, and hard water, remaining unreactive with most chemicals under a wide range of operating conditions, ensuring reliable system performance.

This product has good compatibility with anionic, cationic, and other non-ionic surfactants. It possesses high toxicological safety, is mild and non-irritating, and is easily biodegradable. The acute oral toxicity (rat) LD50 is greater than 2000 mg/kg, classified as low toxicity; skin irritation index is 0 to 0.5, indicating no irritation or very mild irritation; no skin sensitization or genotoxicity.

Technical Parameters

ParameterValue
Product NamePolyethylene Glycol PEG-200
SynonymsPEG 200, Polyoxyethylene 200, Polyethylene Glycol 200, Poly(oxyethylene) 200
CAS No.25322-68-3
Chemical Nameα-Hydro-ω-hydroxypoly(oxy-1,2-ethanediyl)
TypeNon-ionic surfactant
AppearanceColorless, transparent viscous liquid
Acute Oral Toxicity (Rat LD50)>2000 mg/kg (low toxicity)
Skin IrritationNon-irritating or very mildly irritating
BiodegradabilityReadily biodegradable
Storage Temperature15°C to 30°C

Application Suggestions

Daily Chemical and Personal Care Industry: Used as a humectant, lubricant, and viscosity modifier, widely applied in shampoos, body washes, creams, and toothpastes to impart a smooth feel to the skin.

Pharmaceutical and Agricultural Industries: Serves as an ointment base, drug solubilizer, and pesticide emulsifying dispersant, effectively enhancing the bioavailability and use efficacy of active ingredients.

Industrial Casting and Metalworking: Used as a key component of mold release agents and heat transfer fluids, providing excellent high-temperature lubrication and mold release effects.

Chemical Synthesis: Acts as a solvent and synthetic intermediate, participating in chemical reactions such as esterification and etherification, for producing specialty surfactants, polyurethane resins, and plasticizers.

Dye and Ceramic Processing: Used to improve particle dispersion uniformity and as a carrier medium for functional additives.

Precautions

  • Wear safety goggles, protective gloves, and general work clothing during operation. Use in a well-ventilated area.
  • Avoid prolonged contact with eyes and skin. Thoroughly wash hands and exposed skin after operation.
  • Store in a cool, dry, well-ventilated warehouse. Keep containers sealed to prevent moisture absorption. Recommended storage temperature: 15°C to 30°C.
  • Keep away from incompatible substances such as strong acids and strong oxidizing agents. Use stainless steel, polyethylene, or epoxy-lined carbon steel containers for storage.
  • If accidentally splashed into eyes, rinse immediately with plenty of water for at least 15 minutes. If irritation persists, seek medical attention.
  • The product is non-flammable and non-explosive, but keep away from ignition sources and avoid prolonged exposure to air.
  • Waste disposal must comply with local environmental regulations. Do not discharge into sewers, soil, or any water bodies.