Question

What are the physicochemical and technical parameters of Polyether L-64 and Pluronic L64?

Answer
2026-06-06 官方文档 聚醚L-64,Pluronic L64

Polyether L-64 (Pluronic L64) is a nonionic polymer surfactant, appearing as a colorless to pale yellow transparent liquid at room temperature, with an HLB value of about 15, a cloud point of 61°C, and unique low-foaming characteristics. Its physicochemical parameters are comprehensive and suitable for various industrial formulations.

Detailed Description

Polyether L-64 (CAS No.: 9003-11-6), chemical name: polyoxyethylene-polyoxypropylene block copolymer, also known as Poloxamer 184, molecular formula: HO(C₂H₄O)ₓ(C₃H₆O)y(C₂H₄O)ₓH, average molecular weight of about 2900. This product is formed by block copolymerization of propylene oxide (PO) and ethylene oxide (EO). Its unique ABA-type triblock structure imparts excellent interfacial activity and broad compatibility, making it a representative model in the poloxamer series with a balanced hydrophilicity-lipophilicity.

From a physical property perspective, Polyether L-64 is a liquid at room temperature, with a pour point of about -20°C, maintaining good fluidity in low-temperature environments. Its density is approximately 1.06 g/cm³, refractive index between 1.458 and 1.460 (25°C), dynamic viscosity (low shear) of about 900 mPa·s, and kinematic viscosity of about 850 mm²/s. The flash point is greater than 230°C (closed cup), indicating a high flash point substance with low fire risk under normal operating conditions. The product is somewhat hygroscopic and should be stored sealed in a cool, dry place.

Technical Parameters

Parameter Value
Product Name Polyether L-64 / Pluronic L64 (Poloxamer 184)
CAS No. 9003-11-6
Ionic Type Nonionic
Appearance (Room Temperature) Colorless to pale yellow transparent liquid
Molecular Formula HO(C₂H₄O)ₓ(C₃H₆O)y(C₂H₄O)ₓH
Average Molecular Weight Approx. 2900
HLB Value 15
Cloud Point (10% Aqueous Solution) 61°C
Active Content ≥ 99%
pH Value (1% Aqueous Solution) 5.5 - 7.5
pH Value (5% Aqueous Solution) 5.5 - 7.5
Density Approx. 1.06 g/cm³
Kinematic Viscosity (25°C) Approx. 850 mm²/s
Low Shear Viscosity (25°C) Approx. 900 mPa·s
Refractive Index (25°C) 1.458 - 1.460
Flash Point (Closed Cup) > 230°C
Pour Point Approx. -20°C
Surface Tension (0.1% Aqueous Solution, 25°C) Approx. 32 mN/m
Critical Micelle Concentration CMC (25°C) Approx. 0.064%
Hydroxyl Value 28 - 36 mgKOH/g
Acid Value ≤ 0.5 mgKOH/g
Saponification Value ≤ 1 mgKOH/g
Iodine Value ≤ 1
Moisture Content ≤ 0.5%
Heavy Metal Content ≤ 10 mg/kg
Arsenic Content ≤ 2 mg/kg
Solubility Easily soluble in water, ethanol, ether, and other organic solvents
Foaming Characteristics Low foaming
Alkali Resistance Good
Hygroscopicity Hygroscopic
Chemical Stability Stable under general conditions; avoid strong oxidizers

Note: The above data are from the Guoli Chemical product database. Parameters such as amine value, tertiary amine value, free phosphoric acid, monoester/diester content, unsaturation, and penetrating power are not applicable for this product (shown as "None" or "Not available").

Application Suggestions

Polyether L-64 has an HLB value of 15 and a cloud point of 61°C, indicating strong hydrophilicity. It is suitable as an emulsifier for O/W emulsions and as a wetting and dispersing agent in aqueous systems. Its low-foaming property makes it outstanding in high-pressure spray cleaning, CIP online cleaning, and circulating systems. It is recommended to add it during the cooling or dilution stage of formulation development. Moderate stirring ensures uniform dispersion. The specific dosage should be determined through experiments based on the actual application.

Typical dosage reference (adjust according to actual formulation): as a wetting and dispersing agent, 0.1%-1.0%; as an emulsifier, 1%-5%; as a defoaming aid, 0.05%-0.5%.

Precautions

  • The product is hygroscopic. After opening, seal it promptly to avoid prolonged exposure to humid air.
  • GHS classification: Skin irritation Category 2 (H316) and Eye irritation Category 2 (H320). It is recommended to wear protective gloves and goggles during handling.
  • In case of eye contact, immediately rinse with plenty of water for several minutes. Remove contact lenses if present and continue rinsing. If irritation persists, seek medical attention.
  • Store in a cool, dry, well-ventilated place away from strong oxidizers, strong acids, and strong bases, and avoid direct sunlight.
  • Biodegradation rate is low; avoid direct discharge into natural water bodies.