Question 1

Is OP-21 octylphenol polyethoxylate harmful to humans? Does it have an impact on the environment?

Accepted Answer

OP-21 octylphenol polyethoxylate has clear irritant effects on skin and eyes, and is suspected of reproductive toxicity; it is toxic to aquatic organisms and its environmental degradation products have long-term endocrine disrupting effects, requiring strict protection and legal disposal of waste. Detailed Description OP-21 (octylphenol polyethoxylate) is a non-ionic surctant. Although its acute oral and dermal toxicity is low (LD50 >2000 mg\/kg), its health hazards are mainly reflected in local irritation and potential chronic toxicity. Direct contact can cause moderate skin irritation (erythema, dryness, cracking) and severe eye irritation (pain, tearing, congestion); inhalation of heated aerosols or vapors may also cause respiratory discomfort. More alarmingly, animal experiments show that long-term high-dose exposure has reproductive and developmental toxicity, attributed to the estrogen-like activity of the octylphenol group, which may disrupt the endocrine system and affect fertility. In terms of the environment, OP-21 poses a significant risk to aquatic ecosystems. Its ecotoxicity data clearly show that it is toxic to fish, daphnia, and algae (LC50\/EC50 in the range of 1–10 mg\/L). A greater concern is its environmental te: the substance gradually degrades into more persistent octylphenol, which is not easily biodegradable and has stronger endocrine-disrupting activity, tends to accumulate in the environment, and causes long-term adverse effects on aquatic organism reproduction. Overall, the hazard classification of OP-21 includes skin corrosion\/irritation (Category 2), serious eye damage (Category 2A), reproductive toxicity (Category 2), and acute and chronic aquatic hazards (Category 2). GHS pictograms are GHS07, GHS08, GHS09, with the signal word "Warning". Handling and processing must strictly follow safety regulations. Hazard Overview Hazard CategoryHazard Statement (H code)Hazard Class Skin corrosion\/irritationH315 Causes skin irritationCategory 2 Serious eye damage\/eye irritationH319 Causes serious eye irritationCategory 2A Reproductive toxicityH361 Suspected of damaging fertility or the unborn childCategory 2 Aquatic environment – acute hazardH401 Toxic to aquatic lifeCategory 2 Aquatic environment – chronic hazardH411 Toxic to aquatic life with long lasting effectsCategory 2 Ecotoxicological Data Test OrganismTest ParameterData Range Fish96h LC501–10 mg\/L Daphnia48h EC501–10 mg\/L Algae72h ErC501–10 mg\/L * The above data are estimated based on components or similar substances; specific values may fluctuate depending on test conditions. Application Recommendations OP-21, with its excellent emulsifying, wetting, and cleaning abilities, is widely used in textile printing and dyeing, pesticide formulations, coatings, and industrial cleaning. However, in formulation design, especially in consumer products that may come into contact with the human body (such as household detergents), its residual risks need to be fully assessed; in environmentally-releasing applications such as pesticides and water treatment agents, eco-friendly alternatives should be prioritized or emissions strictly controlled. Industrial use must be equipped with engineering controls (e.g., local exhaust ventilation) and strict operating procedures. Precautions Personal protection: Wear protective gloves, protective clothing, and eye\/ce protection (P280) during operation; thoroughly wash skin after handling (P264); receive special training before use (P201). First aid measures: If on skin, wash with plenty of water and soap (P302+P352); if in eyes, rinse cautiously with water for several minutes and remove contact lenses (P305+P351+P338); if irritation persists, seek medical advice (P337+P313). Spillage and disposal: Collect spillage (P391), avoid discharge into water bodies; dispose of contents\/container at an authorized waste cility in accordance with hazardous waste regulations (P501), do not discharge arbitrarily. Storage management: Store in a locked place (P405), away from fire and high temperatures, ensure ventilation and dryness.

Question 2

What should I do if problems occur during the use of OP-21 Octylphenol Polyoxyethylene Ether? How to obtain technical support?

Accepted Answer

If problems occur during the use of OP-21, first consult the product SDS safety data sheet for initial troubleshooting, then contact Haian Guoli Chemical Co., Ltd. for professional technical support. Detailed Explanation During the use of OP-21 Octylphenol Polyoxyethylene Ether (CAS No.: 9036-19-5), due to the ct that this product is a highly active nonionic surctant (active content ≥99%, HLB value about 16), its applications cover multiple fields such as textile printing and dyeing, pesticide formulations, coatings and inks, metalworking fluids, etc. Different process conditions (such as temperature, pH, water hardness, compatibility systems, etc.) can affect the actual performance of the product. When encountering issues such as poor emulsification, insufficient dissolution, abnormal foam, or poor compatibility with other additives, it is recommended to first troubleshoot based on data, then seek professional technical support. Haian Guoli Chemical Co., Ltd. has a professional technical R&D and application service team that can provide professional guidance on issues related to the emulsifying performance, wetting and penetrating properties, dispersion and cleaning ability of OP-21, as well as specific formulation compatibility. Before contacting, it is recommended to prepare the product batch number, storage conditions, usage formula, process parameters, and a detailed description of the specific problem encountered, so that technical personnel can quickly locate the issue and provide effective solutions. Common Problems and Self-Check Methods Common Problem Possible Cause Self-Check Suggestion Difficult dissolution or gel formation Product is paste/solid (melting point approx. 45~50°C), difficult to dissolve at low temperature; direct addition to cold water may cause clumping It is recommended to pre-dissolve or stir in warm water at 40~50°C first, avoiding direct large-scale addition at low temperature Poor emulsion stability, layering OP-21 has an HLB value of 16, strong hydrophilicity, selectivity towards oil phase types; improper dosage or incompatible system Confirm the required HLB value of the oil phase; appropriately adjust the dosage of OP-21 or compound with low-HLB emulsifiers Excessive foam or difficult defoaming High usage concentration or pH changes in the system affecting foam characteristics This product is a medium-to-low foaming type; if foam affects the process, reduce dosage appropriately or add a defoamer Turbidity when combined with anionic/cationic additives High water hardness causing interference from calcium and magnesium ions; or system pH outside the tolerance range of nonionic surctants This product has good hard water resistance; it is recommended to test water hardness; check if system pH is within the 6~8 range Change in product properties (color deepening, layering) Storage temperature too high or storage time too long; product is prone to moisture absorption (deliquescent product) Store in a cool, dry place; seal after use to avoid exposure to high temperature and high humidity environments How to Obtain Technical Support If you encounter the above or other technical issues during the use of OP-21 Octylphenol Polyoxyethylene Ether, you can contact Haian Guoli Chemical Co., Ltd. through the following methods for assistance: Consult product technical documents: First, refer to the Certificate of Analysis (COA) and Safety Data Sheet (SDS) included with the product packaging, which contain detailed product specifications and safe handling information. Contact sales customer service: Contact the sales representative of Guoli Chemical through the original purchasing channel, providing the product batch number and usage issues; the sales representative will coordinate the technical team to provide application support. Technical consultation service: Directly call or email the technical department of Guoli Chemical (specific contact information can be obtained from the company's official website channels), providing complete product information and scenario description to receive targeted technical solutions. On-site technical support: For major process issues or batch application needs, Guoli Chemical can arrange technical engineers to visit the site for process diagnosis and formulation optimization services. Information Recommended to Prepare Before Contacting Product batch number and production date (shown on packaging label) Product storage conditions and storage duration Addition ratio of OP-21 in the current usage formula Process operating temperature, pH, and water quality conditions Specific description of the problem (photos or samples are preferred) Emergency Handling In case of skin or eye contact, immediately follow the first aid measures in the SDS: for skin contact, wash with plenty of water and soap; for eye contact, rinse continuously with clean water for several minutes and seek medical attention. In case of large spills, collect the spillage and dispose of as hazardous waste (P391, P501), and do not discharge into water bodies.

Question 3

How to purchase OP-21 Octylphenol Polyoxyethylene Ether? What is the minimum order quantity?

Accepted Answer

OP-21 can be directly ordered through the Guoli Chemical sales team. The minimum packaging specification is 50kg plastic drum. Please contact the sales team to confirm the specific minimum order quantity and latest quotation. Detailed Description OP-21 Octylphenol Polyoxyethylene Ether (CAS No.: 9036-19-5) is one of the core products of Haian Guoli Chemical Co., Ltd., belonging to high-performance nonionic surctants. According to the company's product database information, the product currently offers the following packaging specifications: 50kg plastic drum, 200kg plastic drum, IBC tote tank, customers can flexibly choose according to actual usage needs. Regarding the minimum order quantity (MOQ), there is no clear parameter in the database. Usually, the minimum order quantity for chemical raw materials is based on the minimum packaging unit, that is, starting from 50kg/drum is common, but specific policies (such as whether single drum orders are supported, sample requests, etc.) are subject to the latest reply from the sales team. It is recommended to contact the Guoli Chemical sales department directly to obtain accurate MOQ and tiered pricing information. The current price data is marked as "Prices for reference only", and the displayed quotation requires contacting the sales team for the latest prices. Chemical raw material prices fluctuate greatly due to multiple ctors such as raw material market conditions, purchase quantity, transportation distance, etc. Direct communication can ensure obtaining the most accurate daily quotation. Basic Product Information ItemParameter Product NameOP-21 Octylphenol Polyoxyethylene Ether CAS No.9036-19-5 AppearanceWhite to light yellow paste or solid Ionic TypeNonionic Surctant Active Content≥99% HLB Value16 Packaging Specification50kg plastic drum / 200kg plastic drum / IBC tote tank ManucturerHaian Guoli Chemical Co., Ltd. Ordering Suggestions Step 1: Clarify Requirements — Determine the required specifications and approximate quantity based on your application scenarios (textile dyeing and printing, pesticide formulations, coatings and inks, detergents, etc.). OP-21 has an active content ≥99%, HLB value 16, outstanding emulsifying and dispersing properties, suitable for various industrial fields. Step 2: Contact the Sales Team — Communicate directly with sales representatives through the Guoli Chemical official website or official contact information. Providing the following information will help quickly obtain accurate quotations: Required quantity (kg or ton) and packaging preference Target application area and process conditions Receiving address (for calculating logistics costs) Whether to request samples for preliminary testing Step 3: Confirm Order Details — Including price terms, delivery time, shipping method, payment conditions, quality inspection standards, and technical support services, etc. Precautions OP-21 is a nonionic surctant, easily soluble in water, chemically stable at room temperature, but easily absorbs moisture. After opening, it should be sealed and stored, recommended to be kept in a dry and ventilated place and locked up. This product has skin/eye irritation and reproductive toxicity risks (GHS classification category 2). Protective gloves, goggles, and protective clothing must be worn throughout the operation, and skin should be thoroughly cleaned after work. Toxic to aquatic organisms with long-lasting effects. Waste and containers must be disposed of in accordance with hazardous waste regulations, and it is strictly prohibited to discharge into water bodies. For first-time use, it is recommended to request small samples for compatibility and process suitability testing before bulk purchase to confirm it meets requirements.

Question 4

Does OP-21 (octylphenol ethoxylate) meet environmental requirements? Can a test report be provided?

Accepted Answer

OP-21 (octylphenol ethoxylate) does not fully meet increasingly stringent environmental requirements. It poses significant risks in terms of aquatic toxicity, endocrine disruption, and environmental persistence. It is not recommended for use in scenarios where APEO substances are restricted. Detailed Explanation OP-21 (octylphenol ethoxylate) belongs to the class of alkylphenol ethoxylates (APEOs) nonionic surctants. According to the safety data from Guoli Chemical, the product has the following core environmental issues: its octylphenol group is difficult to degrade rapidly in the environment, and the degradation product octylphenol has strong endocrine-disrupting activity and can persist in the environment. The product is clearly classified as "Hazardous to the aquatic environment — Acute hazard category 2" and "Hazardous to the aquatic environment — Chronic hazard category 2", and the GHS label includes the environmental hazard pictogram (GHS09). At the international regulatory level, APEO substances (including octylphenol ethoxylates and nonylphenol ethoxylates) have been strictly restricted by various environmental regulations. The EU REACH regulation has included octylphenol in the Candidate List of Substances of Very High Concern (SVHC), restricting its use above certain concentrations. Textile industry standards such as OEKO-TEX Standard 100 and ZDHC (Zero Discharge of Hazardous Chemicals) also set strict limits on APEO residues. Therefore, if your application involves export of textiles, leather products, or targets end markets with strict environmental requirements, the use of OP-21 may pose compliance risks. Regarding test reports: Currently, no third-party environmental test report for OP-21 is directly available in the Guoli Chemical product database. For a complete test report (e.g., SGS test, APEO content test, biodegradability test, etc.), it is recommended to directly contact Guoli Chemical's sales or technical department to confirm whether they can provide batch test reports that meet specific testing standards (e.g., EN 14362-2 for APEO determination in textiles, GB/T 23972, etc.). Key Environmental Risk Parameters Risk CategoryGHS ClassificationHazard Description Acute aquatic toxicityCategory 2H401: Toxic to aquatic life Chronic aquatic toxicityCategory 2H411: Toxic to aquatic life with long-lasting effects Endocrine-disrupting properties—The octylphenol group exhibits estrogen-like activity, interfering with aquatic organism reproduction and development Environmental persistence—The degradation product octylphenol persists in the environment, with a log Kow of approximately 3.5–4.8 Ecotoxicological Data Test SubjectEndpointData Range Fish96h LC501–10 mg/L Daphnia48h EC501–10 mg/L Algae72h ErC501–10 mg/L Note: The above data are estimated based on components or similar substances; actual values may vary depending on product formulation and test conditions. Data source: Guoli Chemical Product Safety Data Sheet. Application Recommendations 1. Alternative evaluation: If the end product needs to comply with regulations such as OEKO-TEX, REACH, or ZDHC, it is recommended to consider using APEO-free nonionic surctants such as tty alcohol ethoxylates (AEO series) or branched alcohol ethoxylates as substitutes. Guoli Chemical offers corresponding alternative products. 2. Compliant usage scenarios: If continuing to use OP-21 in industrial fields without APEO restrictions (e.g., some non-export metalworking fluids, industrial cleaning, etc.), strict wastewater treatment and waste management must be implemented to prevent direct discharge into water bodies. 3. Residue monitoring: For processing industries such as textiles and leather, APEO residue testing should be conducted on finished products after using OP-21 to ensure compliance with downstream customer or export destination limit standards. Precautions Waste must be treated as hazardous waste; do not discharge into water bodies or sewers (Safety statement P391: Collect spillage; P501: Dispose of contents/container in accordance with local/national/international regulations for hazardous waste). Wear protective gloves, protective clothing, and eye protection during operation; avoid skin and eye contact. To obtain product test reports, please contact Guoli Chemical's technical service department directly to confirm the available test items and certification standards.

Question 5

What are the advantages of OP-21 Octylphenol Polyoxyethylene Ether compared to other similar products?

Accepted Answer

According to the technical data from Guoli Chemical, the core advantage of OP-21 Octylphenol Polyoxyethylene Ether lies in its molecular structure of **octylphenol hydrophobic group**, which endows the product with unique chemical stability and application performance. Compared to common tty alcohol polyoxyethylene ethers (such as AEO series) or nonylphenol polyoxyethylene ethers (such as NP/TX series), it excels in **high active matter content, strong tolerance, and broad compatibility**. Detailed explanation is as follows: 1. **Superior chemical tolerance**: OP-21 is a nonionic surctant, and the ether bond structure in its molecule is exceptionally stable. Unlike ester surctants which are prone to hydrolysis under acidic/alkaline conditions, OP-21 maintains excellent surce activity and functional stability over a wide pH range and in hard water systems, without easy deactivation. 2. **Extremely strong emulsification and dispersion ability**: Due to the rigid benzene ring structure of octylphenol, OP-21 has a strong affinity for mineral oils, organic solvents, and pigment particles. With a high HLB value, it is highly effective in preparing oil-in-water emulsions, and its emulsification stability and dispersion/suspension capacity are generally superior to those of linear tty alcohol ethers with the same number of ethylene oxide adducts. 3. **High concentrated active matter content**: Guoli Chemical's OP-21 product has high active matter content. As a concentrated additive, only a small amount is needed to achieve significant wetting, penetration, and cleaning effects, helping to reduce the overall cost of downstream formulations. 4. **Broad compatibility**: As a nonionic product, OP-21 does not ionize in aqueous solution and can be compounded with various auxiliaries such as anionic, cationic, and amphoteric surctants without antagonistic precipitation, offering great formulation flexibility. **Technical parameter comparison (typical values)** | Parameter Characteristic | OP-21 Octylphenol Polyoxyethylene Ether | General tty alcohol polyoxyethylene ether (e.g., AEO-9) | Description | | :--- | :--- | :--- | :--- | | **Hydrophobic group type** | Octylphenol (containing benzene ring) | Linear/branched tty alcohol | Benzene ring structure provides stronger rigid adsorption capacity | | **Ion type** | Nonionic | Nonionic | Both have excellent compatibility, but OP-21 has better tolerance | | **Active matter content** | High concentration (very high) | Generally high | OP-21 has high concentration of active ingredients, resulting in higher usage efficiency | | **Acid/alkali and hard water resistance** | Excellent (strong tolerance) | Good | OP-21 has significant stability advantages under harsh conditions | | **Main application focus** | High temperature/strong alkali scouring, pesticide emulsification, emulsion polymerization | Household cleaning, general degreasing | OP-21 is more inclined towards demanding industrial emulsification and dispersion | **Application Suggestions** Based on its advantages, OP-21 is particularly suitable for systems requiring extremely high emulsion stability. In **pesticide emulsifiable concentrates and emulsion in water**, it ensures rapid dispersion and long-term stability of the spray solution when diluted with water of different hardness; in **emulsion polymerization**, it precisely controls the latex particle size, ensuring smooth synthesis reactions; in **textile scouring** and **paper deinking**, its strong penetration and emulsification abilities significantly improve processing efficiency. **Precautions** Despite its excellent performance, it should be noted that OP-21 contains octylphenol groups. According to the safety technical data from Guoli Chemical, this component may eventually degrade in the environment into octylphenol, which has endocrine-disrupting properties and is toxic to aquatic organisms with long-term effects. Therefore, during use and waste disposal, strict compliance with environmental regulations is required, and discharge into water bodies is strictly prohibited.

Question 6

How to store OP-21 Octylphenol Ethoxylate? What is the shelf life?

Accepted Answer

OP-21 Octylphenol Ethoxylate should be stored sealed in a cool, dry, and well-ventilated warehouse, and the storage area must be locked; under unopened and recommended storage conditions, the typical shelf life is 2 years. Detailed Description OP-21 Octylphenol Ethoxylate (CAS No.: 9036-19-5) is chemically stable at room temperature, but due to its hygroscopic nature, humidity in the storage environment must be strictly controlled. The product appears as a white to light yellow paste or solid, with a melting point between 45~50°C. Therefore, during high summer temperatures, direct sunlight and proximity to heat sources should be avoided to prevent softening or even stratification of the product. According to GHS safety data requirements, this product is classified with hazards including skin irritation (Category 2), serious eye irritation (Category 2A), reproductive toxicity (Category 2), and aquatic environmental hazard (Category 2). Thus, the storage area must be locked (P405) and accessible only to authorized personnel with specialized training. The warehouse should be equipped with emergency spill response cilities, the floor should be impermeable, and the product should be stored strictly separate from food and feed. Regarding shelf life, based on the physicochemical properties of the product and industry practice, under conditions of maintaining original sealed packaging and storage temperature controlled at 5~35°C, the recommended shelf life for unopened product is 24 months from the manucturing date. After opening, it should be used as soon as possible, and the container must be resealed immediately after each use to prevent moisture absorption and contamination. If stored beyond the shelf life, it is recommended to contact the technical department of Guoli Chemical for re-testing, and use only after confirming all specifications are acceptable. Summary of Recommended Storage Conditions Storage ParameterRequirement Storage TemperatureRecommended 5~35°C, avoid extreme high or low temperature Relative HumidityKeep dry environment, avoid high humidity Container ConditionSealed, prevent moisture absorption and entry of foreign matter Storage LocationCool, dry, well-ventilated, locked management Keep Away FromHeat sources, open flames, direct sunlight, strong oxidizers Packaging Specifications50kg plastic drum / 200kg plastic drum / IBC tote Shelf LifeUnopened, recommended 24 months (from date of manucture) Application Recommendations If the product hardens or solidifies due to low-temperature storage, before use, gently heat in a water bath to 40~50°C and stir until homogeneous. Do not use open flames or direct steam heating to avoid local overheating which may cause product decomposition. After opening, remaining material should be sealed promptly and it is recommended to use within 3 months for optimal performance. Precautions The storage area must be locked, accessible only to trained personnel, and strictly comply with GHS P405 preventive requirements. In case of leakage, collect leaked material immediately (P391), avoid entry into drains or natural water bodies, and dispose of waste according to hazardous waste regulations (P501). Shelf life data are based on recommended values under standard storage conditions. Accelerated aging data for this product under extreme storage conditions are not available in the database. For special conditions, please consult the technical department of Guoli Chemical.

Question 7

What safety precautions should be taken when using OP-21 Octylphenol Polyoxyethylene Ether?

Accepted Answer

OP-21 Octylphenol Polyoxyethylene Ether is a GHS-classified hazardous chemical with skin/eye irritation and reproductive toxicity, toxic to the aquatic environment. Full protective equipment must be worn during operation, and discharge into water bodies must be avoided. Hazard Overview According to the GHS classification criteria, OP-21 Octylphenol Polyoxyethylene Ether lls under the following hazard categories: Skin corrosion\/irritation (Category 2), causes skin irritation (H315); Serious eye damage\/eye irritation (Category 2A), causes serious eye irritation (H319); Reproductive toxicity (Category 2), suspected of damaging fertility or the unborn child (H361); Acute aquatic toxicity (Category 2) and Chronic aquatic toxicity (Category 2), toxic to aquatic life with long-lasting effects (H401+H411). GHS pictograms include GHS07 (exclamation mark), GHS08 (health hazard), and GHS09 (environmental hazard). The signal word is "Warning". In terms of health hazards, skin contact may cause moderate irritation, manifested as redness, dryness, and cracking. Eye contact may cause severe irritation, with symptoms such as pain, tearing, conjunctival congestion, and eyelid swelling. Inhalation of vapors or aerosols generated by heating may irritate the respiratory tract, causing coughing and throat discomfort. Ingestion may lead to gastrointestinal irritation symptoms such as nausea, vomiting, and diarrhea. It is particularly important to note that long-term, high-dose exposure in animal experiments has shown significant reproductive and developmental toxic effects, mainly attributed to the endocrine-disrupting properties (estrogen-like activity) of the octylphenol group. Repeated exposure may also affect the liver and kidneys. Key Safety Data Safety IndicatorDataDescription Oral LD50 (Rat)>2000 mg\/kgLow acute oral toxicity Dermal LD50 (Rabbit)>2000 mg\/kgLow acute dermal toxicity Fish 96h LC501–10 mg\/LToxic to aquatic life Daphnia 48h EC501–10 mg\/LToxic to aquatic life Algae 72h ErC501–10 mg\/LToxic to aquatic life pH (1% aqueous solution)6.0–8.0Nearly neutral Flash Point (Closed Cup)>150℃Not flammable SensitizationNot a skin sensitizer— Safety Requirements for Use and Handling Personal Protective Measures (Mandatory) Hand protection: Wear chemical-resistant gloves. Wash skin thoroughly after handling (P264). Eye protection: Wear safety goggles or ce shield to prevent splashes from contacting eyes (P280). Body protection: Wear protective clothing to avoid extensive skin exposure (P280). Respiratory protection: Operate in well-ventilated areas. If aerosols are generated or when heating, it is recommended to wear a dust\/vapor mask. Training before use: Must receive specialized training before use, fully understand the hazardous characteristics of the product (P201). Emergency Response Measures Eye contact (P305+P351+P338): Immediately rinse with plenty of water for several minutes. Remove contact lenses if present and continue rinsing. If eye irritation persists, seek medical attention (P337+P313). Skin contact (P302+P352): Immediately remove contaminated clothing and wash skin thoroughly with plenty of water and soap. If irritation persists, seek medical attention. Inhalation: Move the person to fresh air and keep breathing easy. If symptoms occur, seek medical attention. Ingestion: Rinse mouth. Do NOT induce vomiting. Seek medical attention immediately. Spill containment (P391): Collect spillage promptly. Use inert absorbent material for treatment. Prevent entry into sewers or waterways. If exposed or concerned (P308+P313): If exposed or concerned about exposure, seek medical advice\/attention immediately. Storage and Disposal Storage (P405): Store locked up. Keep away from food, feed, and drinking water sources. Store in a cool, dry, well-ventilated area. Disposal (P501): Dispose of contents and container in accordance with local\/national\/international hazardous waste regulations through qualified treatment cilities. Do NOT discharge into water bodies, sewers, or soil. Special Environmental Safety Warning The environmental risk of OP-21 cannot be ignored. The octylphenol group in the product can gradually degrade in the environment into octylphenol, which has stronger endocrine-disrupting activity, is not readily biodegradable, and is persistent (log Kow approximately 3.5–4.8). Acute toxicity data for fish, daphnia, and algae are all in the range of 1–10 mg\/L, classified as "toxic to aquatic life" and may cause long-term adverse effects on the reproduction and development of aquatic organisms. Therefore, all waste liquids and washing water generated during production and use must not be directly discharged; they must be treated by professional wastewater treatment systems to meet standards before discharge. Key Points to Note In summary, the most critical safety points for using OP-21 can be summarized as follows: ① Wear protective gloves, goggles, and protective clothing throughout the operation; ② Strictly avoid eye contact; if contact occurs, rinse immediately and seek medical attention; ③ Individuals of childbearing age and pregnant women should avoid long-term or repeated exposure (due to reproductive toxicity risks); ④ All waste and washing liquids must not be discharged into water bodies and must be disposed of as hazardous waste in accordance with regulations. Before use, be sure to read the product Safety Data Sheet (SDS) in detail and strictly follow relevant operating procedures.

Question 8

How to use OP-21 Octylphenol Ethoxylate? What is the recommended dosage?

Accepted Answer

OP-21 is a high HLB value non-ionic emulsifier in paste to solid form. It is recommended to pre-dissolve it in warm water or heat to melt before adding to the formulation system. The dosage typically ranges from 0.5% to 10% depending on the application scenario. Detailed Description OP-21 Octylphenol Ethoxylate (CAS: 9036-19-5) is a white to light yellow paste or solid at room temperature (melting point approx. 45~50°C), with an HLB value as high as 16. It is readily soluble in water and belongs to the strongly hydrophilic non-ionic surctant type. Due to its paste/solid form, direct addition may result in slow dissolution and uneven dispersion; pre-treatment before use is recommended: heat OP-21 to above 50°C to melt it into a flowable liquid, or pre-disperse it with 50~60°C warm water to form a slurry or solution before adding to the main formulation system. During the mixing process, avoid prolonged high-speed shearing to prevent excessive foaming (this product is medium to low foaming), and after thorough mixing, check the stability of the system. The cloud point of OP-21 is ≥100°C, indicating that it maintains excellent surce activity and solubility in high-temperature aqueous systems under normal pressure, making it suitable for high-temperature process conditions. As a non-ionic surctant, it has good chemical stability in acids, alkalis, and hard water, and can be used in combination with anionic, cationic, and amphoteric surctants without compatibility issues. Technical Parameters ParameterValue HLB Value16 Active Content≥99% AppearanceWhite to light yellow paste or solid Melting PointApprox. 45~50°C pH Value (1% aqueous solution)5.0~7.0 Cloud Point≥100°C Critical Micelle Concentration (CMC)2.5×10⁻⁴ mol/L Surce TensionApprox. 32 mN/m Foaming CharacteristicsMedium to low foam Penetration Power (1% aqueous solution)>180 s Water SolubilityReadily soluble in water Ionic TypeNon-ionic Application Suggestions and Recommended Dosage The following dosages are typical industrial references for various application fields (based on total formulation weight). The specific dosage should be optimized through experiments according to the actual system and process conditions: Application FieldRecommended Dosage (wt%)RoleUsage Points Textile Dyeing & Finishing (Scouring/Penetration)0.5~3.0Penetrating agent, Scouring agent, Leveling agentResistant to alkali and high temperature, suitable for desizing, scouring, bleaching and other pretreatment processes Leather Processing (Degreasing/tting)0.5~2.0Degreasing aid, tting penetrating agentUsed in warm water systems to promote emulsification and removal of internal t in leather Paper/Waste Paper Deinking0.1~0.5Wetting dispersantStable under alkaline deinking conditions, accelerates ink detachment Industrial & Household Detergents2.0~8.0Main active or co-activeGood emulsifying and removal effect on heavy grease, can be compounded with non-ionic/anionic surctants Pesticide EC/EW Formulations3.0~10.0EmulsifierHLB 16 suitable for O/W emulsions, often used in combination with low HLB emulsifiers Paint/Ink Pigment Pastes0.5~3.0 (based on pigment)Pigment wetting dispersantHelps shorten grinding time, improves paste flowability Emulsion Polymerization1.0~4.0 (based on monomer)Polymerization emulsifierEnsures stable dispersion of monomer droplets and latex particles Metalworking Fluids/Degreasers1.0~5.0Emulsifying cleaning componentEnhances emulsification and cleaning ability for mineral oils and animal/vegetable oils Note: The Guoli Chemical product database does not currently have official standard dosage data for each application scenario. The recommended dosages above are based on product characteristics such as HLB value and CMC value, as well as industry common practices. The optimal dosage in a specific formulation should be determined through experiments based on oil phase type, process conditions, and performance requirements. Precautions Pre-dissolution operation: The product is a paste/solid at room temperature (melting point 45~50°C). It is recommended to pre-dissolve in 50~60°C warm water or heat to melt before addition to ensure rapid dissolution and uniform dispersion. Protective requirements: Wear protective gloves, goggles, and protective clothing during operation to avoid skin and eye contact. This product may cause skin irritation and serious eye irritation (GHS category 2/2A). Environmental control: Contains octylphenol group, toxic to aquatic organisms and has endocrine-disrupting properties. Wastewater must be treated according to relevant regulations and must not be discharged directly into water bodies. Storage conditions: Store in a cool, dry place, and keep under lock (P405). Keep away from children and unauthorized personnel. The product is hygroscopic; seal tightly after opening. Formulation compatibility: OP-21 is a non-ionic surctant with good compatibility with anionic, cationic, and amphoteric surctants. Synergistic effects can be achieved in formulations. Reproductive toxicity warning: Long-term or repeated exposure may cause damage to fertility or the unborn child (H361). Personnel should avoid prolonged high-dose exposure.

Question 9

What are the main industries and processes in which OP-21 octylphenol ethoxylate is applied?

Accepted Answer

OP-21 octylphenol ethoxylate is widely used in eight major industries including textile printing and dyeing, leather processing, papermaking, detergents, pesticide formulations, coatings and inks, emulsion polymerization, and metalworking fluids. In various processes, it primarily serves core functions such as emulsification, wetting and penetration, dispersion, and cleaning. Detailed Description OP-21 (octylphenol ethoxylate (21) EO) is a high-performance nonionic surctant produced by Guoli Chemical, manuctured through the addition polymerization of octylphenol with ethylene oxide. It appears as a white to light yellow waxy paste. With its outstanding emulsifying ability, excellent wetting and penetration properties, efficient dispersion and cleaning performance, as well as resistance to strong acids, alkalis, and hard water, OP-21 is widely used as a multifunctional additive in numerous industrial fields, representing a typical "industrial general-purpose" surctant product. The core advantage of this product lies in its nonionic nature—it does not dissociate in solution and exhibits excellent compatibility with anionic, cationic, and amphoteric surctants, allowing OP-21 to be flexibly formulated into various systems. At the same time, its high active content (high concentration of active ingredients) means that the dosage can be reduced in practical use, thereby lowering overall costs and offering significant economic benefits. It is particularly important to note that the octylphenol group contained in OP-21 has certain persistence in the environment and may cause long-term adverse effects on aquatic organisms. Therefore, during use and waste disposal, relevant environmental regulations must be strictly followed, and wastewater containing this product must not be discharged directly into water bodies. Overview of Application Processes in Various Industries IndustryApplication Process\/StageFunction Textile Printing and DyeingPretreatment scouring, dyeing leveling, fiber penetrationUsed as a penetrant, scouring agent, and leveling agent to improve uniformity of fiber treatment and dye uptake rate, suitable for cotton, synthetic fibers, and blended brics Leather ProcessingDegreasing process, tliquoring processHelps remove natural ts from hides, promotes uniform penetration of tliquoring materials, and improves leather softness and feel Papermaking IndustryPulping, waste paper deinkingActs as a wetting and dispersing agent to accelerate ink detachment and dispersion during waste paper repulping, promote fiber separation, and improve deinking efficiency Detergent IndustryHousehold detergents, industrial detergents, hard surce cleanersProvides detergency, emulsification, and wetting capabilities, effective in removing various types of oily soils Pesticide FormulationsPreparation of emulsifiable concentrates (EC), emulsion in water (EW)Acts as a highly effective emulsifier to ensure rapid dispersion of active ingredients in water and formation of stable emulsions, enhancing dilution stability and efficacy Coatings and InksPigment dispersion, color paste preparationFunctions as a pigment dispersing and wetting agent to shorten grinding time, prevent pigment particle flocculation, improve storage stability, and color development Emulsion PolymerizationFull polymerization processActs as an emulsifying stabilizer to ensure stable dispersion of monomer droplets and polymer latex particles, control particle size, and optimize emulsion performance Metalworking FluidsCutting fluids, degreasers, rust preventivesEnhances cooling, lubrication, and cleaning performance, effectively removes mineral oils and animal\/vegetable ts, and provides synergistic anti-corrosion effects Application Recommendations In formulation design, OP-21 is recommended to be used as a primary or auxiliary emulsifier. With a high HLB value (approximately 15-16, due to the long EO chain structure), it is particularly suitable for constructing O\/W (oil-in-water) emulsion systems. In textile scouring agent formulations, it is advisable to blend with anionic surctants to achieve synergistic effects. In pesticide emulsifiable concentrate formulations, the conventional dosage is 5% to 15% of the active ingredient weight. In coating color paste dispersion, the recommended dosage is 2% to 8% of the pigment weight. Specific dosages should be determined through experiments based on the actual formulation system and process conditions. Precautions Operation Protection: This product may cause skin and eye irritation (GHS Category 2\/2A). Protective gloves, goggles, and protective clothing must be worn during operation. In case of accidental eye contact, rinse immediately with plenty of water for several minutes and seek medical advice. Reproductive Toxicity Warning: This product contains octylphenol groups with endocrine-disrupting properties, suspected of causing damage to fertility or the unborn child (H361). Personnel should avoid prolonged or repeated exposure. Environmental Protection: Toxic to aquatic life with long-lasting effects (H411). Waste must be treated as hazardous waste and must not be discharged into water bodies. Storage Conditions: Store locked up, away from food and feed, and out of reach of children. Read Before Use: Read the Safety Data Sheet (SDS) thoroughly before use, and follow all relevant safety operation procedures and occupational health protection requirements.

Question 10

What are the physicochemical technical parameters of OP-21 Octylphenol Polyoxyethylene Ether?

Accepted Answer

Comprehensive and detailed physicochemical parameters of OP-21 Octylphenol Polyoxyethylene Ether, covering three categories: basic chemical properties, physical properties, and safety-related characteristics, providing complete data reference for formulation development and quality control. Detailed Description OP-21 Octylphenol Polyoxyethylene Ether (CAS No.: 9036-19-5) is a high-performance nonionic surctant with the molecular formula C8H17C6H4O(CH2CH2O)21H (n≈21) and molecular weight of approximately 1130. The product appears as a white to light yellow paste or solid, with consistency varying with temperature changes. It has high active matter content (≥99%), is readily soluble in water, is chemically stable at room temperature, and exhibits excellent resistance to acids, alkalis, and hard water. In terms of surce activity, OP-21 has an HLB value of up to 16, making it a highly hydrophilic emulsifier. Its cloud point is ≥100℃, and the critical micelle concentration (CMC) is 2.5×10-4 mol/L, significantly reducing the surce tension of water to about 32 mN/m. These properties enable it to maintain excellent emulsification, dispersion, and wetting functions even in high-temperature and high-electrolyte systems. Its foam properties are moderate to low foaming, suitable for industrial applications requiring foam control. From a safety physicochemical perspective, the product has a flash point >200℃ (closed cup), is non-flammable, and poses no explosion or oxidation hazards. However, it should be noted that it is irritating to the skin and eyes, classified under GHS as Skin Irritation Category 2 and Serious Eye Irritation Category 2A, and also has reproductive toxicity (Category 2) and aquatic environmental hazards (Acute and Chronic Category 2). Strict adherence to safety operating procedures is required during use. Technical Parameters Basic Chemical Parameters Parameter NameValue/Specification CAS Number9036-19-5 Molecular FormulaC8H17C6H4O(CH2CH2O)21H (n≈21) Molecular WeightApproximately 1130 Ionic TypeNonionic AppearanceWhite to light yellow paste or solid Active Matter Content≥99% Solid Content≥99% Moisture≤0.5% Free Alcohol≤1% Surce Activity and Functional Parameters Parameter NameValue HLB Value16 Cloud Point≥100℃ Critical Micelle Concentration (CMC)2.5×10-4 mol/L Surce TensionApproximately 32 mN/m (Source: Guoli Chemical Database) Penetration Power (1% Aqueous Solution)>180 s (Source: Guoli Chemical Database) Foam PropertiesModerate to low foaming Alkali ResistanceGood Physicochemical Indicator Parameters Parameter NameValue pH Value (1% Aqueous Solution)5.0~7.0 (Product Specification); 6.0–8.0 (Safety Data Sheet, 25℃) pH Value (5% Aqueous Solution)5.5~7.0 Hydroxyl Value45~55 mgKOH/g Acid Value≤0.3 mgKOH/g Saponification Value≤1 mgKOH/g Iodine Value≤0.5 gI2/100g Amine Value≤0.1 mgKOH/g Tertiary Amine Content≤0.1% Unsaturation0 mol/kg Heavy Metals≤10 mg/kg Arsenic≤2 mg/kg Physical Property Parameters Parameter NameValue Melting PointApproximately 45~50℃ DensityApproximately 1.06 g/cm³ Refractive Index1.483~1.487 Kinematic Viscosity (50℃)Approximately 150 mm²/s Low Shear Viscosity (50℃)Approximately 2000 mPa·s Flash Point (Closed Cup)>200℃ (Product Specification); >150℃ (Safety Data Sheet) Solubility

OP-21 Octylphenol Ethoxylate

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Property	Value
CAS No.	9036-19-5
Molecular Formula	C8H17C6H4O(CH2CH2O)21H, n≈21
Appearance	White to pale yellow paste or solid
Ionic Type	Nonionic
Avg. Molecular Weight	Approx. 1130
Cloud Point	≥100
Active Content	≥99
pH Value(1%)	5.0~7.0
pH Value(5%)	5.5~7.0
Iodine Value	≤0.5
Solubility	Readily soluble in water
Surface Tension	~32
CMC	2.5×10^-4 mol/L
Acid Value	≤0.3
Saponification Value	≤1
Hydroxyl Value	45~55
Moisture	≤0.5
Density	~1.06
Kinematic Viscosity	~150 mm²/s (50°C)
Refractive Index	1.483~1.487
Flash Point	>200°C
Hygroscopicity	Readily absorbs moisture
Chemical Stability	Chemically stable at ambient temperature
Amine Value	≤0.1
Tertiary Amine Content	≤0.1%
Penetration	>180 s (1% aq.)
Foam Property	Moderate-low foam
Alkali Resistance	Good
Unsaturation	0 mol/kg
Viscosity	Paste
Melting Point	~45~50°C
Low Shear Viscosity	~2000 mPa·s (50°C)
Solid Content	≥99%
Free Alcohol	≤1%
Heavy Metal	≤10 mg/kg
Arsenic	≤2 mg/kg