Question 1

Is polyether L-61 harmful to the human body? Does it have an impact on the environment?

Accepted Answer

Polyether L-61 is a low-toxicity chemical, which has low harm to the human body under normal use conditions, but direct contact and inhalation still need to be avoided; it has a slight impact on the environment, with a water hazard class of WGK 1 (slightly hazardous). Detailed Description Polyether L-61 (Poloxamer 181) is a non-ionic high-molecular-weight surctant with a low toxicity level. According to the GHS classification in the product safety data sheet, this product is classified as Skin Irritation Category 2 (causes skin irritation), Serious Eye Damage/Eye Irritation Category 2 (causes serious eye irritation), and Specific Target Organ Toxicity - Single Exposure Category 3 (may cause respiratory irritation). The signal word is "Warning," indicating a moderate to low level of hazard, not a highly toxic or extremely poisonous substance. From a practical safety perspective, polyether L-61 has low vapor pressure and low volatility at room temperature, so it does not release large amounts into the air under normal operation. The main risks to humans are concentrated in direct contact and inhalation of vapors/aerosols: prolonged or repeated skin contact can cause dryness, detting, and irritation; splashing into the eyes can cause significant irritation and discomfort; inhalation of vapors generated by heating or spray may lead to respiratory irritation. However, this product is not classified as carcinogenic, mutagenic, or reprotoxic. Under normal industrial use scenarios, the risk is fully controllable as long as appropriate personal protective equipment (chemical safety goggles, chemical-resistant gloves, protective clothing) is worn. Detailed Description Regarding environmental impact, polyether L-61 has a water hazard class of WGK 1 (slightly hazardous to water), which is the lowest hazard level in the German water hazard classification system, indicating a relatively mild impact on the aquatic environment. This is primarily due to its relatively mild ecotoxicological properties as a non-ionic surctant and its lower biological toxicity compared to anionic surctants. Nevertheless, attention should still be paid: after a large spill into water bodies, the inherent properties of the surctant can reduce surce tension, potentially affecting water reoxygenation and aquatic life; the product has a certain persistence in the environment, with a moderate natural degradation rate, and should not be directly discharged into sewers, surce water, or soil. Enterprises should comply with relevant regulations such as the "Law of the People's Republic of China on Water Pollution Prevention and Control," collect wastewater containing this product, and send it to qualified units for treatment. Common treatment methods such as biochemical treatment (activated sludge process) or advanced oxidation can effectively degrade such polyether-type surctants. Technical Parameters Hazard IndicatorLevel/ClassificationDescription Skin corrosion/irritationCategory 2 (H315)Causes skin irritation Serious eye damage/eye irritationCategory 2 (H319)Causes serious eye irritation Specific target organ toxicity (single exposure)Category 3 (H335)May cause respiratory irritation Water hazard class (WGK)WGK 1Slightly hazardous to water Signal wordWarningModerate to low hazard PictogramExclamation mark— Application Recommendations In industrial applications, the safety of polyether L-61 can be effectively ensured through the following measures: Ventilation conditions: Operate in a well-ventilated area, use local exhaust ventilation to avoid accumulation of vapors or mists. Operating temperature: Control within a reasonable range to avoid excessive vapor generation or thermal decomposition products (such as aldehydes, organic acids) at high temperatures. Wastewater treatment: Wastewater containing this product must not be directly discharged into environmental water bodies; it should be collected and treated through a biochemical treatment system before discharge to meet standards. Spill disposal: Use inert adsorbent materials such as sand, vermiculite to collect, and dispose of according to hazardous waste regulations, preventing entry into sewers and soil. Precautions Although polyether L-61 is not a highly hazardous chemical, attention should still be paid during use and storage: store in a cool, dry, well-ventilated place, recommended temperature 5–40°C, keep container tightly closed; keep away from strong oxidizers and ignition sources; wear chemical safety goggles and chemical-resistant gloves (e.g., nitrile rubber) during operation; wash skin thoroughly after handling; if eye contact occurs, rinse immediately with plenty of water for at least 15 minutes and seek medical attention; empty containers may contain harmful residues, do not reuse without cleaning.

Question 2

What should I do if problems occur during the use of polyether L-61? How to obtain technical support?

Accepted Answer

Problems during use of polyether L-61? Immediately refer to the safety data sheet for emergency treatment and contact the Guoli Chemical technical team for professional support. Detailed Explanation When using polyether L-61 (CAS No.: 25322-69-4), if any issues such as abnormal product performance, formulation matching difficulties, or accidental contact occur, the handling procedure should follow the principle of "Safety first, emergency response, seek help promptly". First, quickly determine the nature of the problem: if it involves safety incidents such as inhalation, skin or eye contact, spills, etc., immediate first aid or containment must be carried out according to Section 4 "Emergency Treatment Measures" of the product's Safety Data Sheet (SDS), without delay. After ensuring personnel and environmental safety, proceed with troubleshooting and consultation for process or application-level issues. For application technical issues such as poor emulsification, reduced foam suppression ability, or sedimentation in the dispersion system, they are often related to the formulation system, process conditions, or interactions between raw materials. Common troubleshooting directions include: check whether the product has been stored under recommended conditions (5–40°C, sealed, dry) to avoid deterioration due to prolonged exposure to high temperature or humidity; verify the pH range of the working solution, water hardness, and the presence of strong oxidizers or strong acids/alkalis that may be incompatible with the product; confirm the addition sequence, dosage (usually requires optimization through experiments), and shear conditions during mixing are appropriate. Ways to obtain official technical support from Guoli Chemical: The most direct and efficient method is to contact the sales manager or regional business representative who serves you; they can promptly relay your specific issues to the technical team. You can also call Guoli Chemical's official customer service hotline (please refer to the purchase contract, product packaging, or company website for the specific number). The customer service specialist will record your product batch number, application scenario, and ult description, and transfer the case to an application technical engineer for one-on-one diagnosis and analysis. For complex formulation challenges, Guoli Chemical can provide in-depth support services such as sample retesting, formulation recommendations, or on-site technical exchanges. Technical Parameters Before contacting technical support, it is recommended that you prepare the following key product parameter information to help engineers quickly locate the problem: Parameter ItemTypical Value/SpecificationReference Significance AppearanceColorless to light yellow transparent liquidAbnormal turbidity or layering may indicate product contamination or deterioration Hydroxyl ValueApprox. 28 mg KOH/gKey quality indicator, affects reactivity and emulsifying performance pH Value (1% aqueous solution)5.0–7.5Deviation from this range may affect formulation stability Moisture Content≤0.5%Excessive moisture will interfere with polyurethane foaming reaction and other applications Kinematic Viscosity (25°C)Approx. 400 mm²/sSignificant viscosity change suggests product may have degraded or been contaminated Density (25°C)Approx. 1.02 g/cm³Aids in judging batch consistency HLB Value3Low HLB value, mainly suitable for water-in-oil emulsification and defoaming systems Cloud PointNone (insoluble in water)This product is insoluble in water and will not exhibit cloud point phenomenon in aqueous solution Application Recommendations Based on your specific application field, you can preliminarily investigate the root cause from the following aspects: Polyurethane Foam (Flexible/Rigid): If collapse or uneven cell size occurs, check whether the addition amount of polyether L-61 is within the recommended range of the formulation, and whether the quality and ratio of main materials such as polyol and isocyanate are accurate. Also ensure the material temperature is appropriate to avoid ilure of the foam stabilizer due to excessive temperature. Industrial Defoamer: If the defoaming/antifoaming effect decreases, verify whether there are substances in the system that can "steal" the active components of the defoamer, or whether the pH of the system has changed drastically. The performance of polyether L-61 may degrade under long-term operation in strong acids or bases, so evaluation of co-formulation synergy is needed. Water-based Metalworking Fluids: If lubrication or foam resistance is insufficient, check the dilution ratio of the working fluid, tramp oil content, and microbial contamination. The product itself is insoluble in water, and must be properly emulsified or dispersed to function stably in water-based systems. Textile Printing/Dyeing & Pesticide Formulations: If poor dispersion or emulsion layering occurs, check water hardness, compatibility with other surctants in the system, and whether the homogenization process provides enough energy to disperse polyether L-61 to the required particle size. Precautions Again, emphasize that this product is classified as a skin/eye irritant (H315/H319) and may cause respiratory irritation (H335). During any problem handling process, be sure to wear personal protective equipment such as chemical safety goggles and chemical-resistant gloves. In case of accidental contact injury, follow the first aid measures in Section 4.1 of the SDS, and seek medical attention as appropriate. Do not mix or store this product with strong oxidizers. Please read the attached Safety Data Sheet thoroughly for detailed safety information.

Question 3

How to purchase Polyether L-61? What is the minimum order quantity?

Accepted Answer

To purchase Polyether L-61, please contact the sales team of Guoli Chemical. The price is negotiable, and there is no publicly unified standard for the minimum order quantity. Detailed Description Polyether L-61 (CAS: 25322-69-4) is a nonionic polymer surctant sold by Guoli Chemical. Currently, this product cannot be ordered directly online; procurement must be conducted through offline inquiry and negotiation. The database shows that the product is typically packaged in 20kg woven bags, but specific packaging specifications can be provided as needed (e.g., iron drums or ton drums). Therefore, the final minimum packaging unit can be confirmed through negotiation with the sales team. Since the price of chemical raw materials is significantly affected by market fluctuations, order quantity, transportation distance, and other ctors, the price field in the database is only a reference marker. The actual transaction price shall be based on the latest quotation provided by the sales team. It is recommended that you clearly state the intended use, estimated annual consumption, and preferred packaging method when making an inquiry to obtain a more precise solution. How to Get a Quotation and Place an Order You can complete the procurement through the following steps: 1. Organize your requirements: including product name (Polyether L-61), required quantity (kg or tons), packaging preference (e.g., 20kg woven bags or ton drums), and target application field. 2. Contact the sales department of Guoli Chemical: submit your requirements to the sales staff to request the latest quotation, delivery time, and transportation plan. 3. Confirm the order: after receiving the quotation, both parties confirm the price, delivery date, payment terms, etc., and sign a purchase and sales contract. 4. Arrange shipment: after payment is received or an agreement is reached, the warehouse dispatches the goods as agreed and provides accompanying documents (such as inspection certificates and safety data sheets). Technical Parameters ParameterSpecification Appearance (25℃)Colorless to light yellow transparent liquid Ionic TypeNonionic Hydroxyl ValueApprox. 28 mg KOH\/g Active Content≥99.5% HLB Value3 pH (1% aqueous solution)5.0-7.5 Kinematic Viscosity (25℃)Approx. 400 mm²\/s Density (25℃)Approx. 1.02 g\/cm³ Flash Point>200℃ Precautions This product is classified as an irritant (H315\/H319) under GHS. Wear protective gloves and goggles during handling. The minimum order quantity, current stock availability, and tax-inclusive freight price are all dynamic information. Please always refer to the latest reply from the official sales staff of Guoli Chemical.

Question 4

Does polyether L-61 meet environmental requirements? Can you provide a test report?

Accepted Answer

Polyether L-61 meets general environmental requirements under normal use conditions, with a water hazard class of WGK 1 (slightly hazardous) and low environmental impact; test reports need to be requested from Guoli Chemical's sales or technical department as needed. Detailed Description According to the information in Guoli Chemical's product database, polyether L-61 (Poloxamer 181, CAS number: 25322-69-4) has the following characteristics in terms of environmental compliance: This product is classified as water hazard class WGK 1 (slightly hazardous to water), which is the lowest hazard class in the German water hazard classification system, indicating its relatively low potential impact on the aquatic environment. From a product design perspective, polyether L-61, as a nonionic polymer surctant, features low environmental impact. Its chemical structure allows it to maintain stable activity under a wide pH range and hard water conditions, but this also means the product is not easily biodegradable in the natural environment. Therefore, during wastewater treatment after industrial use, it is recommended to properly treat wastewater containing this product in accordance with local environmental regulations to prevent direct discharge into surce water or groundwater. Regarding test reports, Guoli Chemical's product database currently does not have electronic archives of third-party test reports such as SGS or CTI. If you require specific test reports such as RoHS, REACH, Halogen-Free, or biodegradability, please contact Guoli Chemical's sales or technical department directly, and we will coordinate to provide compliance documents based on your specific needs. Summary of Environmental Compliance Points Item Content Description Water Hazard Class WGK 1 Slightly hazardous to water, lowest hazard class Environmental Impact Low environmental impact Limited impact on the environment under normal use conditions Biodegradability No data in database currently Contact technical department for verification data GHS Classification Skin irritation (Category 2), Eye irritation (Category 2), Respiratory irritation (Category 3) No environmental toxicity-related classification Waste Disposal Dispose of in accordance with local/regional/national/international regulations Do not dispose of freely; must be handed over to qualified agencies for treatment Application Recommendations In industrial applications involving environmental compliance (such as textile printing and dyeing, pesticide formulations, water-based metalworking fluids, etc.), the low water hazard characteristic of polyether L-61 makes it well-suited for environmental adaptability. However, the following points should still be noted: Wastewater should be appropriately treated before discharge to ensure compliance with local discharge standards. In case of leakage, prevent it from entering sewers or water bodies, collect it using inert absorbent materials, and dispose of it as hazardous waste. If your end products need to pass environmental certifications such as OEKO-TEX®, ZDHC, or Bluesign®, please communicate with Guoli Chemical's technical team in advance to confirm the compliance compatibility of the formulation. How to Obtain Test Reports Currently, there is no direct download of test reports in the database. To obtain relevant test reports for this product (such as REACH, RoHS, VOC testing, biodegradability reports, etc.), please contact us through the following methods: Contact Guoli Chemical's sales department, providing specific testing items and standard requirements Contact the technical department to confirm the correspondence between product batches and test data For bulk purchases, we can assist in coordinating third-party testing and issuing targeted reports

Question 5

What advantages does Polyether L-61 have over other similar products?

Accepted Answer

Polyether L-61 stands out in terms of low foam performance, chemical adaptability, and multifunctional integration, making it a highly efficient nonionic surctant with "one agent, multiple uses." Detailed Explanation Polyether L-61 (Poloxamer 181) is a high-performance nonionic polymer surctant under Guoli Chemical, belonging to the block copolymer of propylene oxide (PO) and ethylene oxide (EO). Compared with common nonionic surctants on the market (such as tty alcohol polyoxyethylene ether AEO series, alkylphenol polyoxyethylene ether TX/NP series, or conventional polyethylene glycol PEG products), the most prominent differentiated advantage of Polyether L-61 is its unique combination of low HLB value (3) and extremely low foam. Most nonionic surctants generate a large amount of foam when exerting emulsifying and penetrating effects, while Polyether L-61, while effectively reducing oil-water intercial tension, inherently has very low foaming, and even possesses foam-breaking and foam-suppressing capabilities, making it almost irreplaceable in dynamic processes such as circulating pumping, spraying, and high-speed stirring. Another core advantage is excellent chemical and environmental adaptability. According to Guoli Chemical's product database, Polyether L-61 maintains stable activity over a wide pH range and under hard water conditions, with good alkali resistance, whereas some anionic surctants are prone to deactivation and precipitation in acidic or high-hardness water. Additionally, its moderate rheological properties, with a molecular weight of about 2000 and viscosity of about 400 mm²/s (25°C), make it easy to pump and disperse in formulations, offering operational convenience superior to some high-molecular-weight polyethers (e.g., L-81) or high-viscosity products. Compared to the TX/NP series, which require APEO (alkylphenol polyoxyethylene ether) raw materials, Polyether L-61 has a smaller environmental load, aligning with current green chemistry trends. From the perspective of application breadth, Polyether L-61 can meet a variety of process needs across industries. In the polyurethane foam field, it can serve as both a stabilizer and cell regulator for flexible foam and as an emulsifying and dispersing aid for rigid foam. In industrial defoamers, it is the main active component for breaking and suppressing foam. It also performs excellently in water-based metalworking fluids, textile printing and dyeing auxiliaries, and pesticide formulations. In contrast, most similar products (such as common tty alcohol ethers, oleyl alcohol ethers, etc.) have relatively narrow application scopes and cannot simultaneously cover multiple functions such as lubrication, defoaming, emulsification, and dispersion. Technical Parameters Parameter ItemPolyether L-61 (Guoli Chemical)Advantage Over Similar Products Ion TypeNonionicGood compatibility, can be compounded with anionic/cationic/nonionic HLB Value3Low HLB, strong lipophilicity, suitable for water-in-oil systems and defoaming Foam CharacteristicsLow foam (with defoaming and foam suppression capability)Foam control ability in dynamic processes r surpasses AEO and TX series Active Content≥99.5%High purity, precise formula calculation, minimal impurity interference Hydroxyl ValueApprox. 28 mg KOH/gProvides controllable reactive sites Viscosity (25°C)Approx. 400 mPa·sModerate rheology, convenient for pumping and formula operation Flash Point>200°CHigh flash point, safer in high-temperature processes than low-flash-point solvent-based additives Alkali ResistanceGoodDoes not hydrolyze or deactivate in alkaline formulations Solubility CharacteristicsInsoluble in water, soluble in ethanol, ether, etc.Oil-soluble properties make it preferred for defoamers and emulsifiers in oil-based systems pH (1% aqueous solution)5.0–7.5Near neutral, minimal pH interference with the system, good mildness Heavy Metal Content≤10 mg/kgMeets strict industrial standards (Data source: Guoli Chemical Product Database) Application Suggestions Based on the above advantages of Polyether L-61, the following core application scenarios are recommended: Polyurethane Foam Industry: As a cell regulator for flexible foam, it can adjust cell structure, improving foam feel and resilience; in rigid foam systems, it serves as an emulsifying and dispersing agent, enhancing insulation and compressive strength. Industrial Defoamer Formulations: As the main active component, it is suitable for coatings, adhesives, papermaking, wastewater treatment, and other occasions requiring rapid foam breaking and sustained suppression, especially in dynamic systems like circulating spraying and high-pressure pumping. Water-Based Metalworking Fluids: Provides both boundary lubrication and low foam/antifoam performance, suitable for suppressing foam in high-pressure cutting and grinding processes, extending fluid life. Textile Dyeing and Finishing Auxiliaries: As a low-foam wetting agent and leveling agent, especially suitable for foam-sensitive processes like high-speed jet dyeing and overflow dyeing, reducing color spots and shade variation. Pesticide Formulations: As an emulsifying and dispersing agent for emulsifiable concentrates and suspensions, improving dilution stability and field spreadability and penetration. Precautions Polyether L-61 is insoluble in water. When formulating water-based systems, appropriate dispersion processes or compounding with other co-emulsifiers are required. During operation, it is recommended to wear chemical safety goggles and chemical-resistant gloves (e.g., nitrile rubber) to avoid prolonged skin contact and vapor inhalation. Store in a cool, ventilated area at 5–40°C, keep container tightly closed, away from strong oxidizers and ignition sources. This product has a WGK water hazard class of 1. Waste liquid containing this product must not be discharged directly into surce waters and should be properly treated according to regulations.

Question 6

How should Polyether L-61 be stored? What is its shelf life?

Accepted Answer

Polyether L-61 should be stored in a sealed container in a cool, dry, and well-ventilated area at 5–40°C. Under unopened and proper storage conditions, the typical shelf life is 12–24 months. Detailed Explanation The storage management of Polyether L-61 (Poloxamer 181) directly affects the product's performance and safety. According to the product safety data sheet, it should be stored in a cool, dry, and well-ventilated dedicated warehouse, keeping the container always sealed. The recommended storage temperature range is 5–40°C. Avoid drastic temperature changes and freezing to prevent moisture absorption or quality degradation due to temperature fluctuations. The storage area should be away from heat sources, sparks, open flames, and high-temperature surces, as well as other ignition sources. It should be kept at a safe distance from incompatible substances such as strong oxidizers, strong acids, and strong bases. Regarding the choice of packaging container materials, it is recommended to use materials with good compatibility such as stainless steel, carbon steel, polyethylene (PE), or polypropylene (PP). Special attention should be paid to avoiding containers made of copper, aluminum, and their alloys to prevent incompatible reactions. The floor of the storage area should be made of impermeable material and should be equipped with spill containment cilities (such as dikes or trays) to prevent environmental contamination in case of accidental spills. The product's water hazard class is WGK 1 (slightly hazardous to water). In case of a spill, it should be contained immediately and prevented from entering sewers or surce waters. Standard packaging includes iron drums or IBC totes, with specific specifications available upon request. Regarding the shelf life, the product database states "performance remains stable within the shelf life" without specifying a specific period. However, according to common industry practices for polyether nonionic surctants, under strict compliance with the above storage conditions (sealed, normal temperature, moisture-proof, light-proof) and with the original packaging unopened, the typical shelf life of Polyether L-61 is 12 to 24 months from the date of manucture. It is recommended that users refer to the specific shelf life indicated on the product packaging label or the Certificate of Analysis (COA). Once opened, the product should be used as soon as possible and resealed to prevent moisture and impurities from affecting product quality. Storage Conditions Summary Storage ParameterRequirement Storage Temperature5–40°C, avoid drastic temperature changes Environmental RequirementsCool, dry, well-ventilated; keep container sealed Recommended Container MaterialsStainless steel, carbon steel, polyethylene (PE), polypropylene (PP) Prohibited Container MaterialsCopper, aluminum, and their alloys Incompatible SubstancesStrong oxidizers, strong acids, strong bases Water Hazard ClassWGK 1 (slightly hazardous to water) Typical PackagingIron drums or IBC totes Typical Shelf Life12–24 months (subject to product label; database does not specify a specific period) Application Recommendations To ensure the product maintains optimal performance during storage, it is recommended to establish an inventory management system following the "first in, first out" principle. After each use, immediately seal the container opening to minimize contact with moisture in the air. If the product exhibits abnormalities such as stratification, cloudiness, or significant color changes after long-term storage, small-scale testing is recommended before use to confirm whether performance indicators (such as hydroxyl value, cloud point, etc.) still meet process requirements. For users purchasing in large quantities, it is advisable to confirm the specific batch shelf life information and storage recommendations with GuoLi Chemical sales personnel. Precautions Empty containers may contain hazardous residues; do not use them for other purposes without proper cleaning. Regularly inspect the integrity of containers and packaging; replace or handle any damage, corrosion, or leakage promptly. The storage area should be equipped with spill emergency response materials (such as absorbent pads, sand, etc.). Keep away from food, feed, and drinking water sources; the storage area should be lockable.

Question 7

What safety precautions should be taken when using Polyether L-61?

Accepted Answer

Polyether L-61 is a low-irritation chemical (GHS warning level). During use, it is necessary to protect the skin, eyes, and respiratory tract, and operate in a well-ventilated environment. Detailed Explanation Polyether L-61 (Poloxamer 181) is a nonionic polymer surctant with low irritation to skin and mucous membranes under normal operating conditions, and its water hazard class is only WGK 1 (slightly hazardous to water). However, according to the GHS classification criteria, this product is still classified as a skin irritant (Category 2), eye irritant (Category 2), and respiratory tract irritant (Category 3), so caution should not be relaxed during use. In industrial application scenarios, Polyether L-61 is commonly used in polyurethane foaming, metalworking fluids, textile auxiliaries, and pesticide formulations. Under different process conditions, the product may disperse as sprays, vapors, or mists. Therefore, during circulating pumping, spraying, or high-temperature operations, enhanced ventilation and personal protective measures are especially needed to avoid cumulative irritation risks from prolonged or repeated exposure. In addition, although Polyether L-61 is not classified as a flammable or explosive dangerous good, anti-static measures such as grounding are still recommended during dispensing and transfer, and it should be kept away from incompatible substances such as strong oxidizers, strong acids, and strong bases. Eating, drinking, and smoking are prohibited at the work site. After work, thoroughly wash exposed skin areas and cultivate good occupational hygiene habits. Core Points for Safe Operation Protection CategorySpecific Requirements Engineering ControlsOperate in a well-ventilated area with local exhaust ventilation to avoid accumulation of vapors or mists; if ventilation is insufficient, wear respiratory protection equipment. Eye ProtectionWear chemical safety goggles to prevent contact with splashes or vapors. Hand ProtectionWear chemical-resistant gloves (nitrile rubber, chloroprene rubber recommended). Body ProtectionWear protective clothing to avoid contact with skin and clothing. Respiratory ProtectionWhen ventilation is insufficient or aerosols may be generated, wear appropriate respiratory protection equipment. Hygiene PracticesThoroughly wash hands and exposed body parts after work; eating, drinking, and smoking are prohibited at the work site. Operating TemperatureControl within a reasonable range to avoid excessive vapor or thermal decomposition products. Static Electricity PreventionTake anti-static measures such as grounding during transfer or dispensing. Storage Precautions Polyether L-61 should be stored in a cool, dry, well-ventilated dedicated warehouse with the container tightly closed. The recommended storage temperature is 5–40°C, avoiding drastic temperature changes to prevent moisture absorption or deterioration. Keep away from heat sources, sparks, open flames, and hot surces, and store separately from incompatible substances such as strong oxidizers, strong acids, and strong bases. Packaging container materials should be compatible materials such as stainless steel, carbon steel, polyethylene (PE), polypropylene (PP), and avoid using copper, aluminum, and their alloys. The storage area should be equipped with spill containment cilities (such as dikes or trays), and the floor should be made of impermeable material. Regularly check the integrity of containers and packaging, and replace any damaged ones promptly. Empty containers may contain residual hazardous substances and should not be used for other purposes without proper cleaning. Emergency Response Measures Emergency SituationTreatment Method InhalationQuickly move the person to fresh air and keep respiratory tract open; if breathing difficulty occurs, administer oxygen; if breathing stops, perform artificial respiration immediately and seek medical attention. Skin ContactImmediately remove contaminated clothing and flush skin thoroughly with plenty of running water and soap for at least 15 minutes; if irritation persists, seek medical attention; wash contaminated clothing before reuse. Eye ContactImmediately open eyelids and rinse thoroughly with plenty of running water or saline for at least 15 minutes; if contact lenses are present and easily removable, remove them and continue rinsing; seek medical attention immediately. IngestionDo not induce vomiting; rinse mouth with water; if conscious, give small amounts of water to dilute; never give anything by mouth to an unconscious person; seek medical attention immediately. Spill HandlingContain and collect using sand, vermiculite, or inert absorbent material; place in a sealed container and dispose of as hazardous waste through a qualified agency; prevent entry into sewers and surce waters. FireUse carbon dioxide, dry powder, foam, or water fog for extinguishing; do not use direct water streams; firefighters must wear self-contained positive-pressure breathing apparatus. Disposal Disposal of contents or containers must comply with local, regional, national, and international regulations; do not dump or mix with ordinary waste; hand over to a qualified waste treatment agency for disposal. Important Note This safety information is prepared based on current knowledge and is intended only to guide the safe management of the product. It does not constitute a guarantee of product performance. The user is responsible for evaluating the applicability of the above information under specific use conditions and ensuring compliance with all relevant regulatory requirements. If in doubt, please contact the technical support department of Guoli Chemical or refer to the complete Safety Data Sheet (SDS).

Question 8

How to use Polyether L-61? What is the recommended dosage?

Accepted Answer

The usage method and dosage of Polyether L-61 vary depending on the specific application. It is generally recommended to add it through premixing or dilution, with a typical dosage range of 0.1% to 5%. The optimal dosage should be determined through experiments based on the actual process. Detailed Description Polyether L-61 (Poloxamer 181) is a low-foaming nonionic surctant with an HLB value of approximately 3. It is lipophilic, insoluble in water but dispersible, and soluble in organic solvents such as ethanol and ether. Therefore, in practical use, it is recommended to premix it thoroughly with the oil phase or organic solvent before slowly introducing it into the aqueous system to ensure full dispersion and achieve optimal emulsification, defoaming, or foam stabilizing effects. Directly adding it to an aqueous system may lead to uneven dispersion and reduce efficiency. This product has an active content of ≥99.5%, a density of about 1.02 g/cm³ (25°C), a viscosity of about 400 mPa·s (25°C), a low freezing point of approximately -29°C, and a flash point >200°C. It exhibits good fluidity under normal operating conditions, making it easy to meter and pump. It maintains stable intercial activity over a wide pH range and in hard water conditions, adapting to various complex formulation systems. Technical Parameters ParameterValue/Description AppearanceColorless to light yellow transparent liquid Active Content≥99.5% HLB ValueApprox. 3 Molecular WeightApprox. 2000 Density (25°C)Approx. 1.02 g/cm³ Viscosity (25°C)Approx. 400 mPa·s / Approx. 400 mm²/s pH Value (1% Aqueous Solution)5.0–7.5 Hydroxyl ValueApprox. 28 mg KOH/g Flash Point>200°C Freezing PointApprox. -29°C SolubilitySoluble in organic solvents, insoluble in water Foaming CharacteristicsLow foaming Application Recommendations The following dosages are industry general reference ranges (source: Guoli Chemical product database and application experience; specific amounts need to be confirmed through actual experiments): Application FieldRecommended Dosage (by weight of total formulation)Usage Method Polyurethane flexible foam stabilizer0.5%–2.0%Premix thoroughly with the polyol component before foaming Polyurethane rigid foam emulsification and dispersion aid1.0%–3.0%Add to the polyol or blowing agent premix and stir uniformly Active component in industrial defoamers5.0%–20.0% (in the defoamer formulation)Compound with carrier oil, emulsifiers, etc., as the main active substance Final use concentration of defoamer0.05%–0.5% (in the process medium)Dilute with water or solvent in advance, then slowly add to the foaming system Antifoam and lubricating component in water-based metalworking fluids0.5%–3.0%Add to base oil or concentrate, stir and mix evenly in circulation Low-foaming penetrant/leveling agent in textiles0.1%–1.0% (based on working solution weight)Pre-disperse with a small amount of warm water or alcohol, then add to the dye bath Emulsification dispersant in pesticide formulations1.0%–5.0% (in the formulation)Premix with oil-soluble active ingredients and solvents to prepare emulsifiable concentrate or suspension concentrate Precautions Premixing is key: Since Polyether L-61 is insoluble in water, direct addition to the aqueous phase may cause uneven dispersion. It is strongly recommended to premix it with the oil phase or organic solvent before introducing it into the aqueous system. Dosage requires experimental confirmation: The above dosages are general reference ranges. The actual optimal dosage depends on the formulation system, process conditions, and performance requirements. It is recommended to determine it through gradient experiments. Operational safety: Wear chemical safety goggles and chemical-resistant gloves (nitrile rubber or neoprene) during operation. Use in a well-ventilated area, avoid inhaling vapor or prolonged skin contact. In case of eye contact, rinse immediately with plenty of water for at least 15 minutes and seek medical attention. Storage conditions: Store in a cool, dry, and well-ventilated place at 5–40°C. Keep the container tightly sealed, away from strong oxidizers and ignition sources. The freezing point is about -29°C, and the product remains flowable at low temperatures.

Question 9

What are the main industries and processes where Polyether L-61 is applied?

Accepted Answer

Polyether L-61 is widely used in five major industries: polyurethane foam, industrial defoamers, water-based metalworking fluids, textile printing and dyeing auxiliaries, and pesticide formulations. It is a multifunctional nonionic surctant. Detailed Description Polyether L-61 (Poloxamer 181, CAS: 25322-69-4) is a nonionic polymeric surctant produced by Haian Guoli Chemical Co., Ltd. Its unique hydrophilic-lipophilic block copolymer structure endows the product with excellent intercial activity, broad compatibility, and very low foaming characteristics, allowing it to maintain stable performance in acidic, alkaline, and hard water environments. Leveraging these core advantages, Polyether L-61 plays a key role as a process aid in multiple industrial fields. In the polyurethane industry, Polyether L-61 is an important additive for both flexible and rigid foams. For flexible foams, it acts as a stabilizer and cell regulator, controlling the nucleation and growth of bubbles during the foaming process to achieve fine and uniform cell sizes, preventing collapse and coalescence, and improving hand feel and resilience. For rigid and semi-rigid foams, it functions as an emulsifier and dispersant, promoting the thorough mixing of polyols with blowing agents, flame retardants, and other components, improving material flowability, thereby obtaining a uniform and fine closed-cell structure, enhancing insulation and compressive strength. In other industrial fields, Polyether L-61 also excels: as the main active ingredient in industrial defoamers, its foam-breaking and foam-suppressing capabilities are widely used in coatings, adhesives, papermaking, and wastewater treatment; as a lubricating and anti-foaming component in water-based metalworking fluids, it provides boundary lubrication to reduce friction and wear while effectively suppressing foam generated during high-pressure circulation and spraying; in textile dyeing and finishing, its low-foaming and high-penetration characteristics make it an ideal leveling agent and penetrant; in pesticide formulations, as an efficient emulsifying and dispersing agent, it significantly improves the dispersion stability of oil-soluble pesticides in water and the field application efficacy. Application Fields Application Industry Specific Process/Scenario Functional Role Polyurethane Foam Flexible foam foaming process Stabilizer, cell regulator — refines cell structure, prevents collapse and coalescence Rigid/Semi-rigid Polyurethane Foam Rigid foam pouring, spray molding Emulsifying and dispersing aid — promotes component mixing, improves closed-cell structure and insulation Industrial Defoamers Coatings, adhesives, papermaking, wastewater treatment Main active ingredient — rapid foam breaking, sustained foam suppression Water-based Metalworking Fluids Cutting, grinding, high-pressure spray circulation systems Lubricating and anti-foaming component — provides boundary lubrication, inhibits foam generation Textile Printing and Dyeing Dyeing, penetration pretreatment Low-foaming penetrant, leveling agent — reduces color difference and streaks, improves dyeing uniformity Pesticide Formulations Emulsifiable concentrate, suspension concentrate preparation Emulsifying and dispersing agent — improves dilution stability and efficacy Application Recommendations When selecting Polyether L-61 as a process aid, it is recommended to determine the dosage based on the specific application system: in polyurethane foam formulations, typically add 0.3%–2.0% by weight of the total polyol; in defoamer formulations as the main active ingredient, recommended usage is 5%–30%; in metalworking fluids, typical addition is 0.1%–0.5% of the working fluid; in textile leveling processes, recommended dosage is 0.5–2 g/L; in pesticide formulations as an emulsifier, recommended usage is 3%–8% (all are empirical reference ranges; actual dosage should be determined through system testing). Due to its low-foaming characteristics, this product is especially suitable for dynamic operations such as circulation pumping, spraying, and stirring, effectively reducing equipment malfunctions and process interruptions caused by foam. Precautions This product has a water hazard class of WGK 1 (slightly hazardous to water). Waste liquid after use should be disposed of in accordance with local regulations and must not be discharged directly into water bodies. It is recommended to wear chemical safety goggles and chemical-resistant gloves (e.g., nitrile rubber) during operation, avoiding prolonged skin contact and vapor inhalation. Storage temperature is recommended to be controlled at 5–40°C, keep tightly sealed in a cool, dry, and well-ventilated place, away from strong oxidizers and ignition sources. Packaging container materials should preferably be stainless steel, polyethylene, or polypropylene; avoid using copper, aluminum, and their alloys. In case of accidental eye contact, rinse immediately with plenty of water for at least 15 minutes and seek medical attention; for skin contact, wash thoroughly with soap and water.

Question 10

What are the physicochemical technical parameters of Polyether L-61?

Accepted Answer

Detailed Physicochemical Technical Parameters of Polyether L-61 — A Low HLB Value, Nonionic High-Molecular-Weight Surctant with Multiple Key Indicators Meeting Premium Grade Standards Detailed Description Polyether L-61 (Poloxamer 181, Pluronic L-61, CAS No.: 25322-69-4) is a nonionic polypropylene glycol-based surctant with the molecular formula HO(C3H6O)nH and an average molecular weight of approximately 2000. According to the Guoli Chemical Product Database, this product appears as a colorless to light yellow transparent liquid at room temperature, with an effective content of ≥99.5% and an extremely low HLB value (only 3), making it a typical water-in-oil (W/O) emulsifier. Its unique polyoxypropylene hydrophobic chain segment endows the product with excellent low-foaming properties, chemical stability, and compatibility with organic solvents. Polyether L-61 is insoluble in water but soluble in organic solvents such as ethanol and ether. This characteristic makes it perform excellently in polyurethane foaming systems, industrial defoamers, and oil-based formulations. The hydroxyl value is approximately 28 mg KOH/g, the acid value is controlled at ≤0.5 mg KOH/g, and the iodine value is ≤1, indicating high molecular saturation and stable chemical properties. Moisture content is strictly controlled at ≤0.5%, and free alcohol at ≤0.1%, ensuring no side reactions are introduced in moisture-sensitive systems such as polyurethane. Technical Parameters Parameter ItemTechnical IndicatorRemarks Product NamePolyether L-61Aliases: PPG, Polypropylene Glycol, Poloxamer 181 CAS No.25322-69-4— Molecular FormulaHO(C3H6O)nH— Molecular WeightApprox. 2000— AppearanceColorless to light yellow transparent liquidAt room temperature Ionic TypeNonionic— HLB Value3Water-in-oil (W/O) emulsifier Effective Content≥99.5%— pH Value (1% Aqueous Solution)5.0–7.5— Density (25°C)Approx. 1.02 g/cm³— Kinematic Viscosity (25°C)Approx. 400 mm²/s— Refractive Index (25°C)Approx. 1.452— Freezing PointApprox. -29°CGood low-temperature fluidity Flash Point>200°CHigh flash point, good operational safety Cloud PointNone— Hydroxyl ValueApprox. 28 mg KOH/g— Acid Value≤0.5 mg KOH/g— Iodine Value≤1High saturation, good chemical stability Unsaturation≤0.04 mol/kg— Moisture≤0.5%— Free Alcohol≤0.1%— Heavy Metals≤10 mg/kg— Arsenic≤2 mg/kg— SolubilitySoluble in organic solvents such as ethanol and ether, insoluble in water— Foam CharacteristicsLow foam— HygroscopicityLow— Alkali ResistanceGoodStable over a wide pH range Chemical StabilityStable under normal storage conditions; avoid strong oxidizers— Packaging Specifications20kg woven bagCustomizable iron drums or IBC totes Note: The above data are sourced from the Guoli Chemical Product Database. Some auxiliary parameters have not been tested due to product characteristics; items marked as "None" currently have no data available. Application Recommendations Due to its HLB value of only 3, insolubility in water, and low-foaming properties, Polyether L-61 is highly suitable for applications requiring oil-soluble emulsification and dispersion. In flexible and rigid polyurethane foams, it acts as a foam stabilizer and regulator, promoting thorough emulsification of polyols and blowing agents to obtain fine and uniform cell structures. In industrial defoamer formulations, it can serve as a core active component to quickly eliminate fine foams. In water-based metalworking fluids, it offers both lubrication and anti-foam functions. The recommended dosage depends on the formulation system; generally, a starting test range of 0.5%–3% is advised. Additionally, it can be used as a low-foam penetrant and emulsifying dispersant in textile dyeing and finishing as well as pesticide formulations. Precautions This product is classified under GHS as a Skin/Eye Irritant (Category 2). Wear chemical protective gloves, goggles, and protective clothing during handling. Recommended storage temperature: 5–40°C. Keep tightly sealed in a cool, ventilated area away from strong oxidizers and ignition sources. The freezing point is approximately -29°C; the product remains liquid at low temperatures, but avoid drastic temperature changes. Water hazard class: WGK 1. Do not discharge into water bodies in case of leakage; collect with inert absorbent material for disposal.

Polyether L-61

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Property	Value
CAS No.	25322-69-4
Molecular Formula	HO(C3H6O)nH
Appearance	Colorless to light yellow transparent liquid
Ionic Type	Nonionic
Avg. Molecular Weight	Approx. 2000
Active Content	≥99.5%
pH Value(1%)	5.0-7.5
pH Value(5%)	5.0-7.5
Iodine Value	≤1
Solubility	Soluble in ethanol, ethyl ether and other organic solvents; insoluble in water
Acid Value	≤0.5
Hydroxyl Value	~28 mg KOH/g
Moisture	≤0.5
Density	~1.02 g/cm³ (25°C)
Kinematic Viscosity	~400 mm²/s (25°C)
Refractive Index	~1.452 (25°C)
Flash Point	>200°C
Hygroscopicity	Low
Chemical Stability	Stable under normal storage conditions; avoid strong oxidizers
Foam Property	Low foam
Alkali Resistance	Good
Unsaturation	≤0.04 mol/kg
Viscosity	~400 mPa·s (25°C)
Melting Point	~-29°C (freezing point)
Low Shear Viscosity	~400 mPa·s (25℃)
Solid Content	≥99.5%
Free Alcohol	≤0.1%
Heavy Metal	≤10 mg/kg
Arsenic	≤2 mg/kg

Polyether L-61

Product Details

Applications

Properties

Safety

Product Overview

Performance Features

Application Guidelines

Packaging and Storage

Polyether/Poloxamer Applications

Product Properties

Safety

GHS

Handling

Storage

First Aid

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