Question 1

Is polyether F-38 harmful to the human body? Does it have an impact on the environment?

Accepted Answer

Polyether F-38 is a low-toxicity substance, basically harmless to the human body, and under normal use conditions, it is non-irritating and non-sensitizing to the skin; it is environmentally friendly, easily biodegradable, and has low toxicity to aquatic organisms. Detailed Description Polyether F-38 (Poloxamer 108) is a nonionic surctant, and its toxicological data indicate that the product has high safety. The acute oral toxicity (rat) LD₅₀ value is greater than 5 g/kg, belonging to the low toxicity level. In the skin irritation test (rabbit), no irritating reaction was observed, and the skin sensitization test result was also non-sensitizing. Only eye contact may cause mild reversible conjunctival redness and swelling, without permanent damage. Overall, under normal industrial use conditions, the health risk of polyether F-38 to humans is extremely low. In terms of environmental safety, polyether F-38 also performs well. According to the OECD 301B standard test, its biodegradation rate exceeds 60%, making it easily biodegradable, and it can be rapidly decomposed by microorganisms in the natural environment without causing long-term accumulation. The ecotoxicity data for aquatic organisms (fish/water flea) show that LC₅₀/EC₅₀ are all greater than 100 mg/L, belonging to the low toxicity level, and it is not classified as a substance harmful to the aquatic environment. Therefore, under normal industrial discharge and disposal conditions, the ecological and environmental risk of polyether F-38 is low. This product is non-flammable, non-explosive, chemically stable, and does not decompose to produce harmful substances under normal storage and operating conditions. Only during combustion may it produce carbon monoxide, carbon dioxide, and other irritating or toxic fumes, but this is not a risk under normal use scenarios. Toxicological and Ecotoxicological Parameter Summary Test ItemTest ResultConclusion Acute Oral Toxicity (Rat) LD₅₀> 5 g/kgLow Toxicity Skin Irritation (Rabbit)Non-irritatingSafe Eye Irritation (Rabbit)Mild Irritation (Reversible conjunctival redness and swelling)Requires Protective Measures Skin SensitizationNon-sensitizingSafe Biodegradability (OECD 301B)>60%Readily Biodegradable Acute Fish Toxicity LC₅₀>100 mg/LLow Toxicity Acute Daphnia Toxicity EC₅₀>100 mg/LLow Toxicity Environmental Hazard ClassificationNot classified as a substance harmful to the aquatic environmentEnvironmentally Friendly FlammabilityNon-flammable, no auto-ignition temperatureNon-hazardous Material Application Recommendations Given the low toxicity and environmental friendliness of polyether F-38, this product is particularly suitable for industries with high requirements for safety and environmental protection, such as textile auxiliaries, paper chemicals, and polyurethane foam products. In formulation design, its excellent chemical stability and low-foaming characteristics also help reduce the amount of additives and wastewater treatment burden in subsequent processes. Precautions Eye Protection: Although the irritation is mild and reversible, it is still recommended to wear chemical safety goggles during operation to avoid material splashing into the eyes. Operating Procedures: Wash hands thoroughly after operation, and strictly prohibit eating and smoking in the workplace. Waste Disposal: Although the product has low environmental toxicity, waste should still be handed over to qualified professional organizations for disposal in accordance with national and local environmental regulations, and it is strictly prohibited to discharge directly into sewers or the natural environment. Storage Conditions: Recommended storage temperature is 5°C–40°C. Low temperature may cause the product to solidify or become turbid, but it can be restored by warming and stirring evenly without affecting quality. Incompatible Substances: Avoid contact with strong oxidizers.

Question 2

What should I do if problems occur during the use of Polyether F-38? How to obtain technical support?

Accepted Answer

If problems occur during the use of Polyether F-38, please first identify the cause based on symptoms and prioritize contacting the Guoli Chemical technical team for official support and batch number traceability service. Common usage problems and troubleshooting methods Polyether F-38 (Poloxamer 108) is a nonionic surctant with a high HLB value (30.5) and excellent chemical stability, performing stably under conventional conditions. However, in practical applications, problems may still arise due to improper operation or storage. The following are common abnormal situations and troubleshooting suggestions: 1. Abnormal product appearance (turbidity, stratification, or solidification): Under normal conditions, Polyether F-38 is a colorless to light yellow transparent liquid. Turbidity or solidification is usually related to low-temperature storage - the product's melting point is approximately -10°C, but the recommended storage temperature is 5°C~40°C. Low temperature may cause the product to solidify or become turbid. Simply warm the product to room temperature and stir evenly to restore its original state without affecting product quality. If it does not return to transparent after warming, contamination may exist, and the technical team should be contacted. 2. Application performance not as expected (poor emulsification, wetting, or dispersion effect): First, check whether the addition amount is reasonable; second, confirm the pH value and electrolyte concentration of the formulation system - this product remains stable in acid, alkali, and high-hardness water, but contact with strong oxidants should be avoided. In addition, the product is hygroscopic. If the packaging is not sealed tightly leading to moisture absorption, the effective content (nominal active content ≥99%) may be affected. It is recommended to confirm whether storage conditions meet requirements. 3. Abnormal increase in foam: Polyether F-38 itself is a low-foaming surctant with low foam generation. If abnormal foam occurs, it may be due to synergistic effects of other components in the formulation or contamination of the system by impurities. It is recommended to check raw material compatibility one by one. How to obtain official technical support from Guoli Chemical Hai'an Guoli Chemical Co., Ltd. provides full-process technical support for Polyether F-38 products. If you encounter problems that cannot be solved by the above troubleshooting methods during use, please contact the technical team through the following methods: Technical consultation hotline: It is recommended to call the technical support phone number published on the Guoli Chemical official website, providing the product batch number, purchase date, and specific application process to help technicians quickly locate the problem. Sample shipment for testing: For suspected quality abnormalities, retained samples can be sent to the Guoli Chemical quality inspection department for physical and chemical index re-testing (including key parameters such as hydroxyl value 22.0~28.0, pH value 5.0~8.0, moisture ≤0.05%). On-site technical support: For complex application scenarios such as polyurethane foam, defoamer synthesis, and coating modification, Guoli Chemical can coordinate technicians to provide on-site process diagnosis and formulation optimization suggestions. Emergency safety incidents: In the event of large-scale leakage, personnel contact, or other emergencies, please first perform emergency treatment according to the product safety instructions, then immediately contact Guoli Chemical and obtain the detailed Safety Data Sheet (SDS) to assist subsequent handling. Application recommendations To minimize usage problems, it is recommended to follow the following principles when using Polyether F-38: When using for the first time or switching application formulations, first conduct a small-scale test to confirm compatibility and performance before scaling up production. After opening, the product should be used as soon as possible. Unused portions should be sealed and stored to avoid moisture absorption and contamination. The shelf life under recommended storage conditions is one year (unopened). Wear chemical safety goggles and protective gloves during operation, and maintain good ventilation in the work area. Precautions Polyether F-38 is just one product in the Guoli Chemical series (packaging specification: 20kg woven bag). Different types of polyether products have significantly different performance; do not mix or substitute. Technical parameters in the product database (such as density 1.00~1.10, refractive index 1.452~1.457, cloud point >100°C, etc.) are batch typical values. Refer to the Certificate of Analysis (COA) accompanying the shipment for specific values. If the product is used in special fields such as medicine or food contact, please communicate with the Guoli Chemical technical team in advance to confirm applicability and compliance.

Question 3

How to purchase Polyether F-38? What is the minimum order quantity?

Accepted Answer

Polyether F-38 must be ordered directly from the sales team of Haian Guoli Chemical Co., Ltd. The minimum order quantity is not clearly marked in the product database. It is recommended to contact them directly for the latest policy. Detailed Description Polyether F-38 (CAS: 9003-11-6, also known as Poloxamer 108) is a regular product of Guoli Chemical. According to the product database, the standard packaging specification is 20kg woven bag, but the specific minimum order quantity (MOQ) is not listed separately in the database. For similar products in the chemical industry, the minimum order unit is usually a whole bag or a whole pallet. The specific threshold varies depending on the type of customer (new/existing customers, traders/end users). Regarding product pricing, the database shows "The above prices are for reference only. Please contact the sales team for the latest quote." This indicates that the pricing of Polyether F-38 is dynamically adjusted based on raw material market conditions, order volume, and cooperation model. It is recommended to contact the sales department of Guoli Chemical directly for real-time quotes and minimum order requirements. Technical Parameters ParameterDataData Source Conventional Packaging20kg woven bagGuoli Chemical Product Database Minimum Order QuantityNo clear data availableNeed to confirm with sales Price ValidityDynamic adjustment based on market conditionsGuoli Chemical Product Database Sample PolicyNo data availableNeed to confirm with sales Delivery Lead TimeNo data availableNeed to confirm with sales Application Recommendations Before confirming the purchase, it is recommended to clarify the following information so that the sales personnel can quickly match the appropriate solution: Purpose Description: Whether it is used for polyurethane foam synthesis, defoamer preparation, or coating modification, different application scenarios may require confirmation of batch-specific indicators. Estimated Usage: Providing an estimated monthly/quarterly usage can help obtain better pricing conditions and stable supply assurance. Technical Indicator Requirements: If there are special requirements for parameters such as hydroxyl value (22.0~28.0 mgKOH/g), pH value (5.0~8.0), moisture (≤0.05%), etc., customized batches can be discussed in advance. Precautions Polyether F-38 storage condition is 5°C~40°C. Low temperature may cause the product to solidify or become cloudy. It can be restored by heating and stirring evenly without affecting quality. The shelf life for unopened packaging is usually one year. It is recommended to purchase based on demand to avoid long-term accumulation. The product is non-hazardous and non-flammable. It can be transported via ordinary logistics, but attention should be paid to moisture and sun protection.

Question 4

Does polyether F-38 meet environmental requirements? Can you provide a test report?

Accepted Answer

Polyether F-38 fully meets modern environmental requirements and is a green, environmentally-friendly nonionic surctant. Detailed Description Polyether F-38 (Poloxamer 108) embodies the commitment of Hai'an County Guoli Chemical Co., Ltd. to green chemistry from product design to practical application. This product is low-toxicity, non-irritating to skin, non-sensitizing, and readily biodegradable, meeting the strict requirements of green development in modern industry. According to the OECD 301B standard test, its biodegradation rate exceeds 60%, classifying it as a readily biodegradable substance that can rapidly decompose upon release into the environment without causing long-term ecological accumulation. In terms of ecotoxicity, polyether F-38 exhibits extremely low toxicity to aquatic organisms—the acute toxicity LC₅₀ for fish and EC₅₀ for Daphnia are both greater than 100 mg/L. According to the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) and EU CLP regulations, this product is not classified as hazardous to the aquatic environment, and normal use and discharge will not cause significant harm to the aquatic ecosystem. Key Environmental Compliance Indicators Test ItemResult/DataEvaluation Acute Oral Toxicity (Rat)LD₅₀ > 5 g/kgLow toxicity Skin Irritation (Rabbit)No irritationSafe Eye Irritation (Rabbit)Mild irritation (reversible)Low risk Skin SensitizationNon-sensitizingSafe BiodegradabilityOECD 301B > 60%Readily biodegradable Fish Acute Toxicity LC₅₀> 100 mg/LLow toxicity Daphnia Acute Toxicity EC₅₀> 100 mg/LLow toxicity Environmental Hazard ClassificationNot classified as hazardousEnvironmentally friendly FlammabilityNon-flammable, no auto-ignition temperatureNon-hazardous Application Suggestions With its excellent environmental characteristics, polyether F-38 is especially suitable for the following fields with strict environmental requirements: High-end household polyurethane foam: Meets low-VOC and environmental certification requirements for indoor products such as furniture and mattresses. Textile auxiliaries: Suitable for OEKO-TEX® standard textile processing, without affecting bric ecological certification. Metalworking fluids: Low toxicity ensures operator health and reduces waste liquid treatment pressure. Paper chemicals: Complies with increasingly stringent wastewater discharge standards in the paper industry. Regarding Test Reports Regarding your inquiry about the test report—based on existing data in the database, there is currently no complete test report file for polyether F-38 available for direct download. However, the above environmental data (including biodegradability, ecotoxicity, toxicological indicators, etc.) are standard technical parameters of this product, obtained through standardized test methods. If you require a formal product test report (COA), SGS test report, or third-party test report for specific items, it is recommended that you directly contact the sales or technical department of Hai'an County Guoli Chemical Co., Ltd. They can provide the latest batch test documents and technical support based on your specific needs. Precautions Although polyether F-38 has excellent environmental performance, waste disposal must still comply with legal regulations: waste should be sent to units holding hazardous waste operation permits for incineration or compliant disposal, and it is strictly prohibited to discharge directly into sewers or the natural environment. This is not only a legal requirement but also an important manifestation of corporate environmental responsibility. When storing, please keep containers tightly sealed to avoid leaks and resource waste.

Question 5

What are the advantages of Polyether F-38 compared to other similar products?

Accepted Answer

According to technical data from Guoli Chemical, the core advantages of Polyether F-38 (Poloxamer 108) lie in its extremely high hydrophilicity, excellent safety and environmental characteristics, and multifunctionality in high-end fine chemical applications, giving it a unique position among similar nonionic surctants.Detailed Explanation:Polyether F-38 is a member of the polyoxyethylene-polyoxypropylene block copolymer (Poloxamer) series. Its main advantages are reflected in the following aspects:1. Ultra-high hydrophilicity and HLB value Polyether F-38 has an HLB value as high as 30.5, which is very prominent among nonionic surctants. This means it has extremely strong hydrophilicity, is highly soluble in water, and can serve as an efficient oil-in-water (O/W) emulsifier and solubilizer. In comparison, many conventional nonionic surctants (e.g., tty alcohol polyoxyethylene ethers) typically have HLB values between 10 and 15.2. Excellent safety and low toxicity According to the Guoli Chemical database, Polyether F-38 has clear and excellent safety toxicology data: * Acute oral toxicity (rat): LD₅₀ > 5 g/kg, classified as low toxicity. * Skin irritation (rabbit): Non-irritating. * Skin sensitization: Non-sensitizing. This gives it a tremendous compliance and safety advantage over other surctants that may cause irritation in fields where there is potential contact with the human body, such as personal care, pharmaceutical excipients, and textile auxiliaries.3. Excellent chemical stability and low foaming property This product maintains stable performance in acidic, alkaline, and hard water conditions. At the same time, it is a low-foaming surctant with low foam generation and easy defoaming. In scenarios requiring rapid defoaming or low-foam operation, such as industrial cleaning, metalworking fluids, and textile processes, this is a key application advantage, reducing or eliminating the cost of adding additional defoamers.4. Environmental friendliness and biodegradability Polyether F-38 is readily biodegradable (OECD 301B test, >60%) and exhibits low toxicity to aquatic organisms (LC₅₀/EC₅₀ > 100 mg/L). This meets increasingly stringent environmental regulations and is a key advantage over some traditional surctants with poor biodegradability or higher ecotoxicity.Specific Data Comparison (based on F-38 characteristics):Compared with other general-purpose emulsifiers (such as alkylphenol polyoxyethylene ethers or low-HLB polyethers), the advantageous parameters of F-38 are:| Technical Parameter | Polyether F-38 Typical Value | Advantage Interpretation || :--- | :--- | :--- || HLB Value | 30.5 | Extremely high hydrophilicity, suitable for extreme O/W emulsion systems and scenarios requiring high water solubility. || Cloud Point (1% aqueous solution) | >100°C | Does not il due to cloud point precipitation in high-temperature aqueous systems, r outperforming many similar products with lower cloud points. || Foaming Characteristic | Low foam | Reduces foam issues at the source, especially suitable for use in circulating systems. || Skin Irritation | Non-irritating | Significantly superior to many emulsifiers with clear irritation, making it an ideal choice for developing mild formulations. || Biodegradability | >60% (Readily biodegradable) | Complies with increasingly stringent chemical environmental regulations in the EU, China, and other regions. |Application Recommendations:Based on the above advantages, Polyether F-38 is particularly suitable for:* High-end mild products: e.g., emulsifiers and solubilizers in cosmetics and pharmaceutical excipients.* High-temperature industrial processes: e.g., high-temperature dyeing, oilfield chemicals, where its high cloud point ensures performance stability.* Low-foam formulation systems: e.g., industrial cleaners, metalworking fluids, utilizing its wetting and dispersing functions without foam concerns.* Environmentally sensitive areas: e.g., in water treatment or formulations requiring high biodegradability.Notes:* Low-temperature fluidity: The melting point of the product is around -10°C. Although it is liquid at room temperature, it may become viscous in low-temperature winter conditions. It is recommended to store at room temperature (above 5°C) or gently preheat before use.* Incompatible substances: Avoid contact or mixing with strong oxidizing agents to prevent uncontrollable chemical reactions.* Hygroscopicity: The product is hygroscopic. After opening the package, it should be sealed immediately to avoid moisture absorption.

Question 6

How to store Polyether F-38? What is the shelf life?

Accepted Answer

Polyether F-38 should be stored sealed in a cool, dry, and well-ventilated warehouse. The recommended temperature is 5°C–40°C. The shelf life of unopened original packaging is typically one year. Detailed Description Polyether F-38 (Poloxamer 108) is a nonionic surctant with good chemical stability. It is stable under normal storage and handling conditions, non-flammable, non-explosive, and is classified as a general chemical product. The key to storage management lies in moisture prevention, contamination control, and temperature regulation to ensure the product maintains optimal performance before use. This product may solidify or become turbid under low-temperature conditions, which is a normal physical change. Simply raise the material temperature above room temperature and stir evenly to restore its original state, without affecting product quality. Therefore, even if appearance changes occur during winter storage and transportation, there is no need to worry about product ilure. Summary of Storage Conditions Storage ElementSpecific Requirements Warehouse EnvironmentCool, dry, well-ventilated, away from ignition sources, heat sources, and incompatible substances (such as strong oxidizers) Temperature RangeRecommended 5°C – 40°C Packaging ManagementKeep containers tightly sealed to prevent moisture and contamination; empty containers must not be repurposed without proper treatment Shelf LifeUnder recommended storage conditions, the shelf life of unopened original packaging is typically one year Low-Temperature TreatmentIf solidified or turbid, warm up and stir evenly to restore; does not affect quality Application Recommendations After opening, use as soon as possible. Avoid introducing moisture and impurities when taking material. For long-term storage, it is recommended to immediately seal the container after each use and regularly check packaging integrity. If the product has exceeded its shelf life, perform small-sample performance verification before use to confirm that key indicators (such as hydroxyl value, cloud point, surce activity, etc.) still meet process requirements before deciding whether to continue using. Precautions Keep away from strong oxidizers to avoid dangerous reactions. Do not discharge the product into sewers or the natural environment. Waste disposal must be handled by qualified professional institutions in accordance with regulations. Empty containers may contain residual product, which poses certain hazards; do not use for storing other materials without proper treatment. Warehouses should be equipped with eyewash stations and emergency showers. Operators should wear protective gloves and chemical safety goggles.

Question 7

What safety precautions should be taken when using Polyether F-38?

Accepted Answer

Polyether F-38 is a low-toxicity, non-flammable nonionic surctant with high safety under normal use conditions. However, general chemical handling procedures should still be followed, with emphasis on ventilation protection, avoiding direct eye contact and prolonged skin contact. Detailed Description Polyether F-38 (Poloxamer 108) is a block copolymer of ethylene oxide and propylene oxide. It appears as a colorless to light yellow transparent liquid or paste at room temperature, with no obvious irritating odor. This product is non-flammable and non-explosive, classified as a general chemical rather than a hazardous material. It is chemically stable under normal storage and handling conditions and does not decompose under typical storage conditions. Based on toxicological data, Polyether F-38 exhibits excellent safety: acute oral toxicity (rat) LD₅₀ > 5 g\/kg, classified as low toxicity; it is non-irritating to rabbit skin and non-sensitizing; it only causes mild reversible conjunctival redness and swelling in the eyes. Ecologically, this product is readily biodegradable (OECD 301B standard, degradation rate >60%), and shows low toxicity to aquatic organisms (fish\/daphnia LC₅₀\/EC₅₀ > 100 mg\/L). It is not classified as hazardous to the aquatic environment. Despite the low risk, caution is still required in industrial operations: avoid contact with strong oxidizing agents. Combustion may produce carbon monoxide, carbon dioxide, and other irritating or toxic fumes. Low temperatures (below 5°C) may cause the product to solidify or become cloudy, but it can be restored to its original state by warming and stirring evenly, without affecting product quality. Key Safety Operating Points Engineering Controls and Personal Protective Equipment Ventilation requirements: Production processes should be well-enclosed, and the workplace should maintain good ventilation. Emergency cilities: Eyewash stations and emergency showers should be available in the operating area. Eye protection: Operators should wear chemical safety goggles. Skin protection: Wear appropriate protective gloves and work clothing. Respiratory protection: If concentrations exceed limits or if splashing may occur, it is recommended to wear a respirator or full-ce mask. Operating Guidelines and Prohibitions Avoid contact with skin and eyes; wash hands thoroughly after handling. Do not take work clothing out of the workplace. Avoid leakage; clean up any spills immediately to prevent slipping. Eating, drinking, or smoking is prohibited in the work area. Storage Requirements Storage ConditionSpecific Requirements Warehouse EnvironmentCool, dry, well-ventilated, away from ignition sources, heat sources, and incompatible substances Temperature ControlRecommended storage temperature: 5°C – 40°C Packaging ManagementKeep containers tightly closed to prevent moisture and contamination Shelf LifeTypically one year for unopened containers Special NoteEmpty containers may contain product residues; do not use for other purposes without proper treatment Emergency Response Measures Incident TypeHandling Method Skin ContactImmediately remove contaminated clothing and flush skin with plenty of running water and soap for at least 15 minutes. If irritation or discomfort occurs, seek medical attention. Eye ContactImmediately lift eyelids and flush with running water or saline for at least 15 minutes. Given the possibility of reversible conjunctival redness, seek professional medical care immediately after flushing. InhalationMove to fresh air quickly and keep respiratory tract clear. If breathing difficulties or other discomfort occur, seek medical attention immediately. IngestionRinse mouth thoroughly with water. Do not give anything by mouth to an unconscious person. If feeling unwell, seek medical help immediately and show the safety data sheet. Small SpillAbsorb with inert absorbent material (e.g., dry sand, vermiculite), collect with non-sparking tools into a closed container for disposal. Large SpillContain spill area to prevent spread; suppress vapors with foam. Dispose of waste through a licensed professional waste disposal cility in accordance with regulations. Disposal Waste disposal must comply with national and local environmental regulations. It is recommended to incinerate or undergo other compliant disposal by a unit holding a hazardous waste operation permit. Do not discharge into drains or the natural environment. Notes Although Polyether F-38 is a low-toxicity substance, it is still a chemical and should not be ingested or used for food-related purposes. Solidification or cloudiness at low temperatures is a normal physical phenomenon; it can be restored by warming to room temperature and stirring evenly without affecting product quality. Incompatible substances are strong oxidizing agents; avoid mixing during storage and transportation. Although no known serious hazards from prolonged or repeated exposure, daily protective measures are still recommended to develop good handling habits.

Question 8

How to use Polyether F-38? What is the recommended dosage?

Accepted Answer

The usage and dosage of Polyether F-38 vary depending on the specific application field, acting as an emulsifier, dispersant, or modifying component in different processes. Detailed Explanation Polyether F-38 (Poloxamer 108) is a high-performance nonionic surctant produced by Guoli Chemical, with an HLB value of up to 30.5, a cloud point >100°C, easy water solubility, and excellent emulsifying, wetting, and dispersing capabilities. Its molecular structure is a block copolymer of ethylene oxide (EO) and propylene oxide (PO), with a molecular weight of approximately 5000. It appears as a colorless to light yellow transparent liquid, with low foam and excellent chemical stability, maintaining stable performance in acidic, alkaline, and high-hardness water environments. As a functional additive, the usage of Polyether F-38 varies significantly depending on the target system: in the polyurethane industry, it is added as a core reactive component to the polyol component for flexible foams, rigid foams, and elastomers; in the production of defoamers and demulsifiers, it serves as a synthetic intermediate, used after further esterification or modification; in coatings and adhesives, it is directly added as a modifying component to improve leveling, wetting, and flexibility; in textile auxiliaries, paper chemicals, and metalworking fluids, it is used as a formulation component in compounding. Regarding the recommended dosage, the database currently does not have fixed recommended percentages for each application field. The actual dosage needs to be determined through gradient experiments based on the target properties of the formulation system (emulsifying power, dispersing power, foam control level, etc.). Typically, when used as an additive, the initial test range can refer to 0.1%~5%, and the specific dosage should be verified through process experiments. If you need technical guidance for a specific application scenario, it is recommended to contact the Guoli Chemical technical team for more precise formulation suggestions. Technical Parameters Parameter NameIndicator Product NamePolyether F-38 (Poloxamer 108) CAS No.9003-11-6 Appearance (25°C)Colorless to light yellow transparent liquid Ionic TypeNonionic HLB Value30.5 Cloud Point (1% Aqueous Solution)>100°C Active Content≥99% pH Value (1% Aqueous Solution)5.0~8.0 Hydroxyl Value22.0~28.0 mgKOH/g Density (25°C)1.00~1.10 g/cm³ Kinematic Viscosity (25°C)About 950 mm²/s Surce Tension (0.1%, 25°C)≈43 mN/m Critical Micelle Concentration (CMC)About 0.1% w/v Moisture≤0.05% Flash Point>200°C Freezing PointAbout -10°C SolubilityEasily soluble in water Foam CharacteristicsLow foam Application Recommendations Polyurethane Foam: As a core reactive component added to the polyol system, it participates in the foaming reaction, regulates cell structure and reaction progress, and imparts good foaming fluidity and dimensional stability to the foam. Suitable for flexible foams (furniture, automotive seat cushions), rigid foams (building insulation materials), and semi-rigid foams. Defoamer/Demulsifier Manucturing: As a synthetic intermediate, it is used to prepare efficient defoamers and crude oil demulsifiers through further esterification or modification. Its excellent hydrophilic-hydrophobic balance ability makes it valuable in petroleum extraction and wastewater treatment. Coatings and Adhesives Modification: Directly added to polyurethane coatings, adhesives, and casting elastomer formulations to introduce flexible segments, enhancing flexibility, hydrolysis resistance, and low-temperature impact resistance, while improving leveling and wetting properties. Textile Auxiliaries: Compounded in spinning oils, dyeing auxiliaries, and finishing agents to provide leveling, antistatic, and softening effects, improving the hydrophilic hand feel of brics. Metalworking Fluids: As a formulation component, it provides lubrication and rust prevention properties, enhancing the cleaning and cooling efficiency of cutting fluids. Paper Chemicals: Improves pulp dispersion and paper surce properties. Operational Key Points Low temperature may cause the product to solidify or become cloudy. If this occurs before use, warm it up to above room temperature and stir evenly to restore its original state, which does not affect product quality. The product is hygroscopic. After opening, use it as soon as possible and avoid prolonged exposure to humid air. When compounding, pay attention to compatibility with other components in the system and avoid direct contact with strong oxidizers. Recommended storage temperature is 5°C~40°C. For unopened packaging, the shelf life is one year. Wear chemical safety goggles and protective gloves during operation, and maintain good ventilation in the workplace. Precautions Polyether F-38 is a low-toxicity substance (acute oral LD₅₀ > 5 g/kg), non-irritating to skin, non-sensitizing, and eye contact only causes mild reversible irritation. The product is non-flammable, non-explosive, chemically stable, and easily biodegradable (OECD 301B > 60%), meeting environmental requirements. However, it is still recommended to follow general industrial chemical operating procedures, avoid direct eye contact, and thoroughly wash hands after operation. In case of leakage, collect with inert absorbent material for disposal; do not discharge into drains or the natural environment.

Question 9

In which industries and processes is Polyether F-38 mainly applied?

Accepted Answer

Polyether F-38, with its excellent emulsifying, wetting, dispersing capabilities and low-foaming properties, is widely used in six core fields: polyurethane industry, defoamer and demulsifier synthesis, coatings and adhesives modification, textile auxiliaries, paper chemicals, and metalworking fluids. Detailed Description Polyether F-38 (Poloxamer 108, CAS No.: 9003-11-6) is a nonionic surctant composed of block copolymers of ethylene oxide and propylene oxide, appearing as a colorless to light yellow transparent liquid. Its unique hydrophilic-hydrophobic balanced molecular structure endows the product with outstanding surce activity, excellent chemical stability (stable in acids, alkalis, and hard water) as well as low-foaming and easy-to-control foaming characteristics, making it an ideal functional additive for cross-industry and multi-process scenarios. In the polyurethane industry, Polyether F-38 serves as a core reaction component for synthesizing flexible, rigid, and semi-rigid foams. It effectively adjusts cell structure and reaction progression, imparting excellent foaming fluidity, dimensional stability, and comfortable resilience to the foam. End products cover furniture, automotive seat cushions, and building insulation materials. Meanwhile, its flexible segments can be introduced into polyurethane elastomers to enhance flexibility, hydrolysis resistance, and low-temperature impact resistance. As an intermediate for nonionic surctant synthesis, Polyether F-38, with its good HLB balance ability, is a key raw material for producing high-efficiency defoamers, crude oil demulsifiers, and industrial wetting agents. It holds significant value in petroleum extraction, wastewater treatment, and textile penetration fields. Additionally, in fine chemical formulations, it is used as a functional additive in textile finishing agents (leveling, antistatic), paper chemicals (improving pulp dispersion and paper surce properties), and metalworking lubricants (providing lubrication and anti-rust performance). Specific Application Processes in Various Industries Industry Field Specific Application Process Function Polyurethane Industry Flexible/Rigid/Semi-rigid Foam Foaming, Elastomer Casting Adjust cell structure, improve foaming fluidity, enhance resilience and dimensional stability Defoamer and Demulsifier Defoamer Synthesis, Crude Oil Demulsifier Preparation, Industrial Wetting Agent Formulation Provide hydrophilic-hydrophobic balance ability, serve as key synthesis intermediate Coatings and Adhesives Polyurethane Coating Modification, Adhesive Formulation, Leveling Additive Improve leveling, wetting, adhesion, and hydrolysis resistance Textile Auxiliaries Spinning Oils, Dyeing Auxiliaries, Finishing Agents Leveling, antistatic, improve bric hydrophilic hand feel Paper Chemicals Pulp Dispersion Treatment, Paper Surce Treatment Enhance pulp dispersion, improve paper surce properties Metalworking Fluids Cutting Fluids, Lubricant Formulations Provide lubrication, anti-rust, improve cleaning and cooling efficiency Application Suggestions In practical applications, it is recommended to adjust the dosage of Polyether F-38 according to specific process requirements. When used as an emulsifier or wetting agent, the typical recommended addition amount is 0.1%–5% of the total formulation weight; the optimal ratio should be determined through small-scale trials. Its low-foaming property is especially suitable for high-speed stirring, spraying, or circulation systems that require rapid defoaming, reducing the reliance on additional defoamers. If the product solidifies or becomes turbid due to low-temperature storage, warming it to room temperature and stirring evenly will restore its original state without affecting product performance. This product is chemically stable under normal storage conditions but should be avoided contact with strong oxidizers. Precautions This product is a low-toxicity substance; rat acute oral LD₅₀ > 5 g/kg, non-irritating and non-sensitizing to skin, eye contact causes only minor reversible irritation. It is recommended to wear chemical safety goggles and protective gloves during operation, and ensure good ventilation in the workplace. The product is readily biodegradable (OECD 301B, >60%), with low toxicity to the aquatic environment (LC₅₀/EC₅₀ > 100 mg/L), meeting environmental requirements. Recommended storage temperature is 5°C–40°C; unopened packaging has a typical shelf life of one year.

Question 10

What are the physicochemical technical parameters of Polyether F-38?

Accepted Answer

Polyether F-38 is a non-ionic surctant with an HLB value as high as 30.5. At room temperature, it is a colorless to light yellow transparent liquid, featuring low foaming, easy solubility in water, and excellent chemical stability. Its molecular weight of approximately 5000 makes it perform outstandingly in emulsification and dispersion applications. Detailed Description Polyether F-38 (CAS No.: 9003-11-6), chemically named polyoxyethylene-polyoxypropylene block copolymer, also known as Poloxamer 108. Its molecular structure is HO(C₂H₄O)x(C₃H₆O)y(C₂H₄O)xH, belonging to the non-ionic surctant category. It appears as a colorless to light yellow transparent liquid, slightly hygroscopic, with a freezing point of about -10°C. At low temperatures, it may solidify or become turbid, but it can be restored by warming and stirring without affecting performance. This product exhibits excellent surce activity, with a cloud point of greater than 100°C for a 1% aqueous solution, a surce tension of approximately 43 mN/m at 0.1% concentration (25°C), and a critical micelle concentration of about 0.1% w/v, indicating it can effectively reduce intercial tension at low concentrations. Meanwhile, the product generates low foam volume, making it a low-foaming type suitable for scenarios requiring rapid defoaming or low-foam processes. It has good chemical stability in acid, alkali, and high-hardness water environments, but is incompatible with strong oxidizing agents. Technical Parameters Parameter ItemSpecification/ValueRemarks CAS No.9003-11-6— Molecular WeightApprox. 5000— AppearanceColorless to light yellow transparent liquid— Ionic TypeNon-ionic— HLB Value30.5Extremely hydrophilic Cloud Point (1% Aqueous Solution)>100°C— pH Value (1% Aqueous Solution)5.0~8.0— pH Value (5% Aqueous Solution)5.0~7.5— Active Content≥99%— Moisture Content≤0.05%— Density (25°C)1.00~1.10 g/cm³— Kinematic Viscosity (25°C)Approx. 950 mm²/sLow shear viscosity approx. 950 mPa·s Refractive Index (25°C)1.452~1.457— Freezing PointApprox. -10°CMay become turbid or solidify at low temperatures Flash Point>200°CNon-flammable Hydroxyl Value22.0~28.0 mg KOH/g— Acid Value≤0.05 mg KOH/g— Saponification Value≤0.5 mg KOH/g— Iodine Value≤0.5 g I₂/100g— Unsaturation≤0.05 mol/kg— Surce Tension (0.1%, 25°C)≈43 mN/m— Critical Micelle Concentration (CMC)Approx. 0.1% w/v— SolubilityEasily soluble in water— Foaming CharacteristicsLow foaming— Heavy Metals (as Pb)≤10 mg/kg— Arsenic (As)≤2 mg/kg— Chemical StabilityStableAvoid contact with strong oxidizing agents Packaging Specification20kg woven bag— Shelf LifeOne year (unopened, 5~40°C)— Application Suggestions With an ultra-high HLB value of 30.5 and excellent surce activity, Polyether F-38 is particularly suitable as an oil-in-water (O/W) emulsifier and efficient wetting dispersant. In the polyurethane industry, it serves as a core reactive component for flexible foam, rigid foam, and elastomers; in the synthesis of defoamers and crude oil demulsifiers, it acts as a key intermediate; in coatings and adhesives, it functions as a modifying component to enhance flexibility and adhesion; in textile auxiliaries, paper chemicals, and metalworking fluids, it plays roles in leveling, antistatic, dispersing, and lubricating. The recommended dosage should be determined through specific formulation experiments. Precautions Storage Temperature: Store in a cool, dry, and well-ventilated place at 5°C~40°C. If solidified at low temperatures, it can be restored by warming and stirring without affecting quality. Incompatibilities: Avoid contact with strong oxidizing agents; it does not decompose under normal conditions, but may produce CO, CO₂, and irritating fumes when burned. Safe Handling: Although it is low-toxicity, non-skin-irritating, and non-sensitizing, it is recommended to wear protective goggles and gloves during operation to avoid prolonged exposure. If it comes into contact with eyes, it may cause reversible conjunctival redness and swelling; flush immediately with plenty of water for at least 15 minutes and seek medical attention. Environmental Disposal: Readily biodegradable (OECD 301B >60%), discharge after wastewater treatment to meet standards, and dispose of waste packaging through qualified treatment units.

Polyether F-38

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Property	Value
CAS No.	9003-11-6
Molecular Formula	HO(C2H4O)x(C3H6O)y(C2H4O)xH
Appearance	Colorless to pale yellow transparent liquid
Ionic Type	Nonionic
Avg. Molecular Weight	Approx. 5000
Cloud Point	>100°C (1%aq. soln.)
Active Content	≥99%
pH Value(1%)	5.0~8.0
pH Value(5%)	5.0~7.5
Iodine Value	≤0.5
Solubility	Readily soluble in water
Surface Tension	≈43 mN/m (0.1%, 25°C)
CMC	~ 0.1% w/v
Acid Value	≤0.05
Saponification Value	≤0.5
Hydroxyl Value	22.0~28.0
Moisture	≤0.05
Density	1.00~1.10
Kinematic Viscosity	~ 950 mm²/s (25°C)
Refractive Index	1.452~1.457 (25°C)
Flash Point	>200°C
Hygroscopicity	Hygroscopic
Chemical Stability	Stable; avoid strong oxidizers
Foam Property	Low foam
Alkali Resistance	Good
Unsaturation	≤0.05 mol/kg
Viscosity	~950 mPa·s (25°C)
Melting Point	~ -10°C
Low Shear Viscosity	~950 mPa·s (25°C)
Solid Content	≥99%
Heavy Metal	≤10 mg/kg
Arsenic	≤2 mg/kg

Polyether F-38

Product Details

Applications

Properties

Safety

Product Overview

Performance Features

Packaging and Storage

Polyether/Poloxamer Applications

Product Properties

Safety

GHS

Handling

Storage

First Aid

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