According to the Safety Data Sheet (SDS) of Guoli Chemical, Polyether L-63 is classified as a non-hazardous substance under the GHS classification system, with no hazard category, no pictogram, and no signal word. Toxicological data indicates that its acute oral toxicity LD50 (rat) is greater than 5000 mg/kg, belonging to the actually non-toxic level. It is non-irritating to the skin (based on OECD 404 rabbit test) and non-sensitizing via respiratory or skin contact. Special attention is needed: this product may cause mild temporary eye irritation (based on OECD 405 test). In case of accidental eye contact during operation, immediately rinse with plenty of water for several minutes. If irritation persists, seek medical attention promptly.
Under normal industrial operating conditions, using this product according to basic industrial hygiene practices is safe. It is recommended to wear chemical protective gloves (e.g., nitrile or neoprene gloves), chemical safety goggles or face shield, and work in a well-ventilated area.
The environmental impact of Polyether L-63 is generally low. Acute aquatic toxicity tests show that the LL50 (for fish, algae, or daphnia) is greater than 100 mg/L, placing it in the low toxicity category for aquatic organisms. Regarding biodegradability, based on the OECD 301F method, the degradation rate is greater than 60% ThOD, indicating that it is readily biodegradable and will not persist in the natural environment. Additionally, this product has no significant bioaccumulation potential and is not classified as having persistent, bioaccumulative, or toxic (PBT) properties or very persistent, very bioaccumulative (vPvB) risks.
Although the environmental risk is low, care should still be taken to prevent direct discharge of untreated product into drains, waterways, or soil. In case of spillage, use inert absorbent materials (such as sand, vermiculite) to collect and dispose of in accordance with local regulations at licensed waste treatment facilities.
| Evaluation Item | Test Method/Standard | Result | Conclusion |
|---|---|---|---|
| Acute Oral Toxicity | LD50 (Rat) | >5000 mg/kg | Actually non-toxic |
| Skin Corrosion/Irritation | OECD 404 (Rabbit) | Non-irritating | Safe |
| Eye Damage/Irritation | OECD 405 | Mild temporary irritation | Requires protection |
| Skin/Respiratory Sensitization | — | Non-sensitizing | Safe |
| Acute Aquatic Toxicity | LL50 (Fish/Algae/Daphnia) | >100 mg/L | Low toxicity |
| Biodegradability | OECD 301F | Degradation rate >60% ThOD | Readily biodegradable |
| Bioaccumulation | — | No significant accumulation potential | Low risk |
| PBT/vPvB Assessment | — | None | Low risk |