Question

What are the main components of Span S-40?

Answer
2026-05-17 官方文档 司盘S-40

The main component of Span S-40 is sorbitan monopalmitate, with a content ≥99%, of which monoester is about 55% and diester about 45%. It is a high-purity nonionic surfactant mixture.

Detailed Description

The chemical name of Span S-40 is sorbitan monopalmitate (also known as sorbitan monopalmitate), CAS No. 26266-57-9, molecular formula C22H42O6, molecular weight about 402.6. This product is a nonionic surfactant obtained by the esterification of sorbitol (after dehydration to form sorbitan) with palmitic acid (hexadecanoic acid). It appears as a white to pale yellow waxy solid, melting point 45~47°C, insoluble in water, but soluble in hot oils and various organic solvents.

From the perspective of component composition, Span S-40 is not a single compound but a mixture of sorbitan palmitates. According to measured data from the Guoli Chemical Product Database, the monoester content (one molecule of sorbitan combined with one molecule of palmitic acid) is about 55%, the diester content is about 45%, free alcohol (unreacted polyol) ≤1%, and moisture ≤1.5%. This natural ratio of monoester to diester endows the product with excellent water-in-oil (W/O) emulsifying ability, with an HLB value of 6.7, making it especially suitable as an emulsifier for water-in-oil emulsions.

As a nonionic surfactant, Span S-40 has good chemical stability and wide compatibility. Its acid value ≤8 mg KOH/g, saponification value 140~150 mg KOH/g, hydroxyl value 255~290 mg KOH/g, iodine value ≤10, reflecting high saturation of fatty acid chains and good oxidative stability. The product complies with food additive standards such as FDA 21 CFR 172.842, and has extremely high safety (rat acute oral LD50 > 10 g/kg). It is widely used in food, cosmetics, pharmaceuticals, pesticides and other fields.

Technical Parameters

ParameterSpecification
Active Ingredient Content≥99%
Monoester Contentabout 55%
Diester Contentabout 45%
Free Alcohol≤1%
Moisture≤1.5%
Acid Value≤8 mg KOH/g
Saponification Value140~150 mg KOH/g
Hydroxyl Value255~290 mg KOH/g
Iodine Value≤10
HLB Value6.7
Heavy Metals (as Pb)≤10 mg/kg
Arsenic (As)≤2 mg/kg

Application Suggestions

Based on its main component characteristics (nonionic, HLB 6.7, W/O emulsifying tendency), Span S-40 performs outstandingly in the following scenarios:

  • Cosmetic creams/lotions: Recommended dosage 1%~5%, can be combined with Tween series (e.g., Tween-40) to adjust HLB value, producing W/O creams with fine skin feel.
  • Food emulsification: Suitable for baking fats, whipped cream, etc., recommended dosage 0.1%~1%, complies with FDA food additive standards.
  • Pharmaceutical cream base: As a pharmaceutical excipient, combined with Tween-type emulsifiers can form stable O/W or W/O cream bases.
  • Pesticide emulsifiable concentrate/aqueous emulsion: Recommended dosage 2%~8%, providing good emulsifying dispersibility and spray liquid wetting and spreading ability.

Precautions

  • This product is insoluble in water; when preparing, first dissolve and disperse in hot oil or organic solvent.
  • Not resistant to strong alkaline environment; avoid coexistence with strongly alkaline substances in the formulation.
  • Storage temperature recommended below 35°C; keep packaging sealed, away from heat and strong oxidizers.
  • When using solid product, avoid generating dust inhalation; wash hands after handling.