Question 1

Is Tween-81 harmful to humans? Does it have an impact on the environment?

Accepted Answer

The main hazard of Tween-81 to humans is eye irritation (GHS Category 2), with low toxicity under normal use; for the environment, this product has good biodegradability, but direct discharge into water bodies should still be avoided. Detailed Explanation According to safety data in the Guoli Chemical product database, the primary risk of Tween-81 regarding human health hazards is serious eye irritation (H319), classified as GHS eye irritation Category 2 with the signal word "Warning." Under normal industrial and daily chemical usage conditions, the acute toxicity of this product is low, and it is not classified as highly toxic or carcinogenic. However, direct contact with eyes may cause significant irritation and discomfort; prolonged or repeated skin contact may also cause mild irritation. In case of accidental ingestion, seek immediate medical attention and do not induce vomiting. Regarding environmental impact, Tween-81, as a polyoxyethylene sorbitan monooleate nonionic surctant, has ester and ether bonds in its molecular structure that can be gradually degraded by microorganisms in the natural environment, and it is generally considered biodegradable. However, the database does not provide specific ecotoxicological data for this product (such as LC50/EC50 values). As a surctant, if it enters water bodies in large quantities, it may have certain effects on aquatic organisms (e.g., fish, algae); therefore, the leak handling instructions explicitly require "avoid entry into sewers or water bodies." Overall, under the premise of following standard operating procedures and proper handling, the risks of Tween-81 to human health and the environment are controllable. Industrial users should strictly comply with the protection and disposal requirements in the safety instructions. For ordinary consumers using end products containing this ingredient (such as cosmetics and food), the concentration is within a safe range, and there is no need for excessive concern. Safety Parameter Summary ItemContent GHS Hazard ClassificationEye Irritation (Category 2), H319 PictogramGHS07 (Exclamation mark) Signal WordWarning Main Health HazardCauses serious eye irritation Acute Toxicity (Oral/Dermal)No specific LD50 data available (classified as low toxicity) BiodegradabilityBiodegradable (common property of nonionic surctants) Ecotoxicological DataNo specific data available Storage Temperature5°C to 30°C Application Recommendations In applications involving direct human contact, such as cosmetics, food, and pharmaceuticals, Tween-81 is typically added as an emulsifier and solubilizer at levels ranging from 0.5% to 5% of the total formulation. This concentration range has been validated through long-term use and demonstrates good safety. In industrial applications such as pesticides, coatings, and metalworking fluids, operators should strictly wear protective gloves and safety goggles to avoid direct contact of the undiluted product with skin and eyes. Precautions Eye protection is paramount: Always wear chemical safety goggles during operation. If splashed into eyes, immediately rinse with plenty of water for at least 15 minutes and seek medical attention. Avoid direct discharge: Collect waste liquid and rinse water and dispose of according to local regulations; do not discharge into sewers, surce water, or groundwater. Spill handling: For small spills, contain with inert absorbent materials (e.g., sand, diatomaceous earth), collect in a sealed container, and dispose of in accordance with regulations. Fire response: Use water fog, alcohol-resistant foam, dry powder, or carbon dioxide for fire extinguishing. Storage requirements: Keep containers tightly closed, away from heat sources and strong oxidizers, and avoid freezing and overheating.

Question 2

What to do if problems occur during the use of Tween T-81? How to get technical support?

Accepted Answer

Don't panic if you encounter problems with Tween T-81; first determine whether it is a personal contact issue or a product performance issue, then handle it accordingly, and you can directly contact Guoli Chemical for technical support. Emergency Personal Contact Handling (must be prioritized) According to the product safety data sheet, Tween T-81 is classified as Eye Irritation Category 2 (H319), which may cause serious eye irritation. In case of contact, immediately perform the following first aid: Inhalation discomfort: Immediately move the person to fresh air and keep breathing unobstructed. If discomfort persists, seek medical attention immediately. Skin contact: Remove all contaminated clothing and thoroughly rinse the affected area with plenty of running water and soap. If symptoms such as redness or stinging occur, seek medical help. Eye contact (critical): This is the most concerning situation. Immediately separate the eyelids with fingers and rinse continuously and gently with plenty of water or saline for at least 15 minutes. If contact lenses are worn, remove them after 5 minutes of rinsing, then continue rinsing. If there is still stinging, redness, or other irritation in the eyes after rinsing, seek medical attention immediately and present the chemical safety label of this product. Accidental ingestion: Rinse the mouth immediately with water, do not induce vomiting. Seek medical attention quickly and provide the doctor with the full product name (Polyoxyethylene (5) sorbitan monooleate) and CAS number (9005-65-6). Product leakage: Personnel should quickly evacuate the leakage area. Under the premise of ensuring safety, wear chemical protective gloves and goggles, cover and collect the leaked liquid with dry sand, diatomaceous earth, or other inert absorbent materials, and place it in a sealed chemical waste container. Do not allow the leaked material to enter sewers or any open water bodies. Product Performance or Formulation Problem Troubleshooting If the expected effect is not achieved in the application, such as unstable emulsion, precipitation, or layering, you can troubleshoot from the following aspects: Mismatch of Hydrophilic-Lipophilic Balance (HLB) value: The HLB value of Tween T-81 is 10. Used alone, it can form an oil-in-water (O/W) emulsion. If the emulsification effect is poor, it is generally recommended to compound it with low HLB value Span series (such as S-80). By combining them, the overall HLB value of the system can be precisely adjusted to achieve optimal emulsion stability. It is recommended to start with a small amount of compounding and gradually test to the ideal ratio. Insufficient or excessive dosage: The recommended dosage depends on the type and content of the oil phase, usually 1%-5% of the total formulation. Too low a dosage can easily lead to incomplete emulsification, while too high may cause foam and affect the system viscosity. You can start with 2% and fine-tune up and down for optimization. Unsuitable process conditions: The temperature, homogenization speed, and time during emulsification are crucial. It is recommended to heat the oil phase and water phase separately to the same temperature (usually 50-70°C), then slowly add the water phase to the oil phase for homogenization. The homogenization speed and time need to be determined through small-scale tests. Compatibility with strong electrolytes or acidic/alkaline systems: Although Tween T-81 has certain chemical stability, its emulsification efficiency may decrease under extreme pH conditions (such as strong acids or bases) or high-concentration electrolyte systems. It is recommended to conduct small-scale compatibility tests before use. How to Obtain Official Technical Support from Guoli Chemical If the problem cannot be solved through the above troubleshooting, or if it involves complex compounding systems or requires customized solutions, it is recommended to directly contact the technical team of the manucturer — Hai'an Guoli Chemical Co., Ltd. . You can prepare the following core information so that engineers can quickly locate the problem: Specific product name and batch number (see the label on the barrel) Your specific application field (such as cosmetics, pesticides, metal processing, etc.) Detailed description of the problem encountered (such as appearance, stability, process abnormalities, etc.) Your current formulation system and process conditions (can be discussed under a confidentiality agreement) You can find the latest technical service hotline, email address, or online technical consultation entry through the official website of Hai'an Guoli Chemical Co., Ltd., product brochures, or procurement channel pages to obtain more in-depth application guidance. Technical Parameter Reference The following provides the core technical indicators of Tween T-81 for reference when debugging formulations: Parameter ItemTypical Value Product FormAmber oily liquid HLB Value10 Active Content≥97% Density (25°C)1.00 - 1.05 g/cm³ Hydroxyl Value (mgKOH/g)65 - 85 Saponification Value (mgKOH/g)45 - 55 Cloud Point (1% Aqueous Solution)50 - 60°C pH Value (1% Aqueous Solution)5.0 - 7.0 Flash Point>150°C (Data source: Guoli Chemical Product Database)

Question 3

How to purchase Tween T-81? What is the minimum order quantity?

Accepted Answer

To purchase Tween T-81, please contact the sales team of Guoli Chemical. Normally, it is sold by full drums, and the specific minimum order quantity is subject to business confirmation. Detailed Explanation Tween T-81 (CAS: 9005-65-6) is one of the core products of Hai'an County Guoli Chemical Co., Ltd., belonging to nonionic surctants. According to Guoli Chemical's product database, this product currently offers two standard packaging specifications: 50kg/drum and 200kg/drum, both in well-sealed plastic drums. The minimum order quantity is usually based on full drums, and the specific minimum order quantity may vary depending on inventory, production batch, or customized requirements. The current product price column shows "The above prices are for reference only. For actual prices, please contact the sales team to obtain the latest quotation." Chemical raw material prices are affected by multiple ctors such as upstream raw material costs, market supply and demand, and purchase volume, adopting a dynamic pricing mechanism, so a fixed unit price cannot be provided here. It is recommended that you contact the sales manager directly through Guoli Chemical's official website or official phone number to obtain an instant quotation and procurement contract details. Procurement Process and Logistics Information Inquiry and Selection: Contact Guoli Chemical's sales department, inform them of the required product name (Tween T-81), purity requirement (≥97%), and intended use. The technical team can assist in confirming product suitability. Order Confirmation: Clarify the purchase quantity, packaging specification (50kg or 200kg), delivery cycle, and settlement method. Logistics and Delivery: Usually transported by land logistics. Specific freight and delivery range are determined by the sales team based on the receiving address. Sample Request: If this is your first time using this product, it is recommended to request a sample from Guoli Chemical for formulation testing to confirm effectiveness before bulk purchase. Technical Parameters Parameter ItemTypical Value/Specification Product NameTween T-81 (Polysorbate 81) CAS No.9005-65-6 AppearanceAmber oily liquid Effective Content≥97% HLB Value10.0 Ionic TypeNonionic Standard Packaging50kg / 200kg plastic drum Quotation MethodContact sales team for latest quotation Precautions Is this product a hazardous chemical? Tween T-81 is classified under GHS as Eye Irritation Category 2 (H319), which is only irritating and not a hazardous chemical, but it should still be handled in accordance with chemical regulations. During storage, keep the container tightly closed and store in a cool, dry, well-ventilated area, away from direct sunlight, and avoid mixing with strong oxidizers. Specific procurement contracts, delivery periods, and minimum order quantities are subject to the final business confirmation of Hai'an County Guoli Chemical Co., Ltd.

Question 4

Does Tween T-81 meet environmental requirements? Can you provide a test report?

Accepted Answer

Tween T-81 is a nonionic surctant with low environmental risk, exhibiting good performance on conventional environmental indicators. However, there is no specific environmental certification or test report information in the database. It is recommended to contact the sales department of Guoli Chemical for the latest compliance documents. Detailed Explanation Tween T-81 (Polyoxyethylene (5) sorbitan monooleate), as a nonionic surctant, has ester and ether bonds in its molecular structure that possess a certain degree of degradability in the natural environment. According to Guoli Chemical's product database, the heavy metal content of this product is controlled at ≤10 mg/kg, and the arsenic content is ≤2 mg/kg, both at low levels, meeting conventional environmental control requirements. In the GHS hazard classification, Tween T-81 is only classified as eye irritation (Category 2, H319) and is not listed in hazard categories such as acute aquatic toxicity, chronic aquatic toxicity, or persistent organic pollutants, indicating its potential impact on aquatic ecosystems is relatively small. In various industrial applications, Tween T-81 has been widely used in strictly regulated fields such as food, pharmaceuticals, and cosmetics. These industries have high thresholds for toxicological safety and environmental compatibility of raw materials, indirectly confirming that this product has good environmental adaptability. However, it is important to note that in the event of a spill, direct discharge into sewers or water bodies should be avoided. The product should be collected with inert absorbent materials and disposed of according to regulations, which is standard practice for responsible use. Technical Parameters ParameterValue/Description Heavy Metal Content≤10 mg/kg Arsenic (As) Content≤2 mg/kg GHS Aquatic Toxicity ClassificationNot listed (no acute/chronic aquatic toxicity hazards) BiodegradabilityNo specific biodegradation rate data available for reference Environmental Certifications (REACH/RoHS, etc.)No relevant certification records in the database Application Recommendations If you need to use Tween T-81 in exported products or end applications with clear environmental compliance requirements (such as EU REACH regulations, China's "Measures for the Environmental Management of New Chemical Substances", etc.), it is recommended to directly contact the sales or technical team of Guoli Chemical to obtain the latest product compliance statements and test reports (such as biodegradability test reports, RoHS test reports, updated MSDS/SDS, etc.). Test data for different batches may vary slightly, and the official documents issued by the manucturer shall prevail. Precautions In case of a spill, use inert materials (such as sand, diatomaceous earth) to contain and collect the product. Never discharge it into sewers or natural water bodies. The product itself has no toxicological hazards, but it is classified as eye irritant (H319) under GHS. Protective goggles should still be worn during operation. Store in a cool, dry place at 5°C to 30°C, keep the container tightly sealed, and avoid freezing and extreme temperatures.

Question 5

What are the advantages of Tween T-81 compared to other similar products?

Accepted Answer

The core advantage of Tween T-81 lies in its unique 5 EO chain length and HLB value of 10, which clearly distinguish it from other Tween series products in terms of water-in-oil emulsification, oil affinity, and formulation flexibility. Detailed Description Tween T-81 (Polyoxyethylene (5) Sorbitan Monooleate), compared to other Tween series products from Guoli Chemical, the most fundamental difference is that its molecular structure contains only 5 polyoxyethylene (EO) units, while Tween T-80, T-60, T-20 and other products have 20 EO units. This structural difference directly determines that T-81 has a lower hydrophilic-lipophilic balance value (HLB=10), making it a typical water-in-oil emulsifier, whereas the HLB values of other Tween products generally range from 14.9 to 16.7, leaning towards oil-in-water systems. This means that when preparing oil-based or water-in-oil formulations, Tween T-81 is a more direct and efficient first choice among the Tween series. Secondly, Tween T-81 demonstrates excellent oil affinity and broad solvent compatibility. Compared to T-80 and T-20, T-81 can more effectively emulsify and solubilize various mineral oils, vegetable oils, and essential oils, forming finer and more stable emulsions or microemulsion systems. Additionally, when compounded with the Span series (sorbitan tty acid esters), Tween T-81 allows for fine-tuning the overall HLB value of the formulation over a wider range. This compounding flexibility provides formulation engineers with a precise adjustment method when simultaneously using high-HLB and low-HLB emulsifiers, a unique advantage that high-HLB Tween products find difficult to match. In terms of chemical stability and environmental tolerance, Tween T-81 also stands out. It can maintain surce activity over a wide pH range, withstand acids, bases, and hard water environments, and is less prone to adverse reactions with electrolytes. This gives it better formulation adaptability and long-term stability in demanding industrial applications such as pesticide formulations and metalworking fluids compared to some similar products. Technical Parameters Parameter Name Tween T-81 Tween T-80 Tween T-60 Tween T-20 Chemical Name Polyoxyethylene (5) Sorbitan Monooleate Polyoxyethylene (20) Sorbitan Monooleate Polyoxyethylene (20) Sorbitan Monostearate Polyoxyethylene (20) Sorbitan Monolaurate Number of EO Units 5 20 20 20 HLB Value 10 Approx. 15 Approx. 14.9 Approx. 16.7 Appearance (25°C) Light yellow to amber oily liquid Light yellow to amber viscous liquid Light yellow to amber paste/wax Light yellow to amber viscous liquid Cloud Point (1% Aqueous Solution) 50-60°C Approx. 90°C Approx. 85°C Approx. 95°C CAS Number 9005-65-6 9005-65-6 9005-67-8 9005-64-5 Hydroxyl Value (mg KOH/g) 65~85 65~80 80~96 96~108 Saponification Value (mg KOH/g) 45~55 45~55 40~50 40~54 Note: HLB values and cloud point data for similar products are partially sourced from general literature; actual values may vary slightly due to product specifications. All parameters for T-81 are sourced from Guoli Chemical's product database. Application Recommendations First Choice for Water-in-Oil (W/O) Systems: If your formulation is oil-based or requires emulsifying a large amount of grease, Tween T-81, with its low HLB value (10), can be used directly as the primary emulsifier, a role that other high-HLB Tween products cannot fulfill. Emulsifying Difficult Oils: In cleansing products such as makeup remover oils and bath oils, it has excellent emulsifying and solubilizing capabilities for essential oils and vegetable oils, resulting in a clear product appearance and good rinseability. Compounding to Adjust HLB Scenario: When the total HLB requirement of the formulation system is low (e.g., 5~8), using high-HLB Tweens alone is difficult to achieve. By compounding Tween T-81 with the Span series, the HLB value can be flexibly adjusted to achieve more precise emulsification effects. This is its core synergistic advantage. Pesticide Emulsifiable Concentrates and Emulsions in Water: As a key emulsifier, Tween T-81 ensures uniform dispersion of the active ingredient, enhancing the wetting and spreading ability of the spray solution on plant leaves, thereby improving efficacy. Metalworking Fluids: Provides excellent emulsion stability and boundary lubrication auxiliary functions, helping to extend tool life, suitable for demanding machining environments. Precautions Tween T-81 has a low cloud point (50-60°C); phase separation may occur in high-temperature aqueous solution systems; evaluation should be based on actual process temperatures. Due to its low HLB value, if preparing oil-in-water (O/W) emulsions, T-81 should not be used alone; it must be compounded with high-HLB emulsifiers. Storage temperature should be controlled between 5°C and 30°C, avoiding freezing and overheating, and keeping the container tightly sealed.

Question 6

How to store Tween T-81? What is the shelf life?

Accepted Answer

Tween T-81 should be stored sealed in a cool, dry, and well-ventilated environment, with the temperature controlled between 5°C and 30°C; under proper storage conditions, the general shelf life is 2 years (from the date of production). Detailed Explanation Tween T-81 (Polyoxyethylene (5) sorbitan monooleate) is a nonionic surctant with relatively stable chemical properties, but proper storage conditions are crucial to ensure long-term product performance. This product is an amber oily liquid. Improper storage may lead to oxidative deterioration, stratification, or microbial contamination, affecting its core functions such as emulsification, solubilization, and dispersion. Regarding the shelf life, no specific duration is indicated in the product database. Based on industry common practice and the characteristics of nonionic surctants, under strict adherence to storage conditions, the recommended usage period for Tween T-81 is generally 2 years (from the date of production). It is recommended to refer to the specific shelf life indicated on the product packaging or the Certificate of Analysis (COA), and follow the "first in, first out" principle for inventory management. Storage Conditions Storage RequirementSpecific Instructions Storage EnvironmentA cool, dry, and well-ventilated place Temperature Range5°C to 30°C, avoid freezing and overheating Container RequirementsKeep the container tightly closed, use corrosion-resistant, well-sealed containers, and clearly label them AvoidancesKeep away from heat sources, sparks, open flames, and incompatible substances such as strong oxidizers Regular InspectionRegularly inspect containers for signs of damage or leakage Application Recommendations After each use, immediately seal the container to minimize prolonged exposure of the product to air. For bulk storage users, it is recommended to aliquot the product into smaller containers for individual use to avoid repeatedly opening the same package and introducing contamination. If any abnormal changes in appearance (e.g., significant darkening of color, turbidity, or stratification) or odor are observed, discontinue use and perform quality testing. Precautions During winter storage, special attention should be paid to freeze prevention. Temperatures below 5°C may cause increased viscosity or even turbidity. If this occurs, place the product in a warm environment to slowly return to room temperature and stir gently. Do not heat directly. Wear protective gloves and safety goggles during handling (this product is classified as Eye Irritant Category 2, H319), and avoid contact with eyes and skin. It is recommended to use the product within 6 months after opening to ensure optimal performance. Dispose of waste containers and expired products in accordance with local regulations; do not discard arbitrarily or mix with general waste.

Question 7

What safety precautions should be taken when using Tween T-81?

Accepted Answer

The most critical safety risk when using Tween T-81 is serious eye irritation (H319). Protective goggles/ce shield and gloves must be worn during operation to avoid contact with eyes and skin. Detailed Explanation Tween T-81 (polyoxyethylene (5) sorbitan monooleate) is classified under GHS hazard category Eye Irritation Category 2, with pictogram GHS07 (exclamation mark) and signal word "Warning". Although its overall toxicity is low, accidental eye contact during operation can cause serious eye irritation, making eye protection the most important safety concern when using this product. As a non-ionic surctant, Tween T-81 is chemically stable under normal conditions and does not readily undergo vigorous reactions with other substances. However, this does not mean that safe operating procedures can be ignored. During industrial production and formulation blending, operations involving heating, stirring, and pouring should be carried out in a well-ventilated environment to avoid prolonged inhalation of vapors or mists. After work, hands and exposed skin should be thoroughly washed. For storage, Tween T-81 should be kept sealed in a cool, dry, and well-ventilated place. The storage temperature should be controlled between 5°C and 30°C, avoiding freezing and overheating. Containers should be kept away from heat sources, sparks, and open flames, and stored separately from incompatible substances such as strong oxidizing agents. Key Safety Parameters Safety ItemSpecific Requirement GHS Hazard ClassificationEye Irritation (Category 2), H319 PictogramGHS07 (Exclamation mark) Signal WordWarning Hazard StatementH319 Causes serious eye irritation Storage Temperature5°C — 30°C, avoid freezing and overheating Incompatible SubstancesStrong oxidizing agents Personal Protective Equipment Requirements Eye Protection: Chemical safety goggles or ce shield (most critical) Hand Protection: Suitable protective gloves Body Protection: Wear suitable protective clothing. Remove and wash contaminated clothing before reuse after operation. Respiratory Protection: Operate in well-ventilated areas to avoid inhalation of vapors or mists. Emergency Response Guidelines Eye Contact (Highest Priority) Immediately separate eyelids and rinse continuously with plenty of water or saline solution for at least 15 minutes. If wearing contact lenses and it is easy to do so, remove them during the rinse. If eye irritation persists after rinsing, seek medical attention immediately. This is in accordance with Precautionary Statements P305+P351+P338 and P337+P313. Skin Contact Immediately remove contaminated clothing and wash skin thoroughly with plenty of soap and water. If irritation or discomfort persists, seek medical attention. Ingestion Rinse mouth with water immediately. Do NOT induce vomiting. Seek medical attention promptly. Show the safety data sheet or container label to the doctor. Spill Handling Evacuate personnel to a safe area. Wear personal protective equipment. Contain and collect the spill with inert absorbent material (e.g., sand, diatomaceous earth) and place in a sealed container for disposal according to regulations. Avoid discharge into drains or water bodies. Fire Response Use water spray, alcohol-resistant foam, dry powder, or carbon dioxide for extinction. Firefighters must wear self-contained breathing apparatus and full protective clothing. Precautions Read and understand the complete safety instructions before operation; do not operate based on experience alone. No eating, drinking, or smoking during use. Follow good industrial hygiene practices. After work, thoroughly wash skin according to Precautionary Statement P264. Regularly inspect storage containers for signs of damage or leakage. Use corrosion-resistant, well-sealed containers for storage, and label them clearly.

Question 8

How to use Tween-81? What is the recommended dosage?

Accepted Answer

Tween-81, as a nonionic surctant with an HLB value of 10.0, combines multiple functions of emulsification, solubilization, wetting, and dispersion. The specific dosage needs to be determined through experiments based on the application system, usually ranging from 0.5% to 15%. Detailed Explanation Tween-81 (Polyoxyethylene (5) Sorbitan Monooleate) is a high-quality nonionic surctant produced by Guoli Chemical. At room temperature, it is an amber oily liquid, easily soluble in oils and organic solvents, and can be dispersed in water. Its HLB value of 10.0 is in the middle of the hydrophilic-lipophilic balance, allowing it to be used as an oil-in-water (O/W) emulsifier or, by compounding with lipophilic emulsifiers such as Span series (e.g., Span 80, Span 60), flexibly adjust to a lower HLB value to build a stable water-in-oil (W/O) system. With excellent chemical stability (resistant to acid, alkali, and hard water), good wetting and penetration ability (surce tension about 30-35 mN/m), and broad formulation compatibility, Tween-81 has mature applications in daily chemicals, food, pharmaceuticals, pesticides, and industrial fields. When using Tween-81, the addition method should be chosen according to the specific process requirements. If used as an emulsifier, first dissolve Tween-81 in the oil phase to be emulsified, then slowly add the water phase under stirring. If necessary, use high-pressure homogenization or a colloid mill to refine the emulsion. If used as a solubilizer, pre-mix Tween-81 with the substance to be solubilized (such as flavors, essential oils, lipophilic active ingredients), then gradually add water and dilute to obtain a clear or bluish opalescent stable system. When compounding with the Span series, the ratio of the two directly affects the final HLB value. The Griffin formula (HLB blend = HLB-A × WA% + HLB-B × WB%) can be used for calculation to match the oil phase emulsification requirements. Technical Parameters Parameter Item Value Description HLB Value 10.0 Hydrophilic-Lipophilic Balance value, suitable for O/W emulsification and adjusting system HLB through compounding Active Content ≥97% High purity ensures stable application effect Cloud Point (1% aqueous solution) 50-60°C Reflects the thermal stability boundary of the aqueous system Surce Tension Approx. 30-35 mN/m Indicates its ability to reduce intercial tension; the lower the value, the better the wetting and spreading property Critical Micelle Concentration (CMC) 0.01-0.1 g/L Above this concentration, micelles can be effectively formed to exert solubilization and emulsification effects pH Value (1% aqueous solution) 5.0-7.0 Nearly neutral acidity and alkalinity, gentle to the formulation system Acid Value ≤2 mgKOH/g Low acid value ensures formulation stability Hydroxyl Value 65~85 mgKOH/g Can be used for subsequent chemical modification reactions such as esterification Application Recommendations Based on Guoli Chemical's product database and common industry experience, the recommended dosages of Tween-81 in different applications are as follows (optimal dosage needs to be verified by experiments): Application Field Functional Role Recommended Dosage (wt%) Usage Instructions Cosmetic Creams/Lotions Emulsifier 1 ~ 5% Use in combination with Span 80 or Span 60 to enhance emulsion stability; pre-heat and dissolve in the oil phase before use Makeup Remover Oil/Bath Oil Solubilizer, Wetting Agent 3 ~ 12% Emulsifies upon contact with water, providing a pleasant rinse-off feel; can be used as primary or auxiliary emulsifier Food (Ice Cream, Margarine, etc.) Emulsion Stabilizer 0.1 ~ 1% Must comply with food additive usage standards; recommended to add during the oil melting stage Oral/Topical Pharmaceutical Preparations Solubilizer, Emulsifier 0.5 ~ 5% Used to improve the bioavailability of poorly soluble drugs; dosage should be validated with formulation process Pesticide Emulsifiable Concentrate/Microemulsion Key Emulsifier 5 ~ 15% (based on total formulation weight) Better effect when compounded with anionic emulsifiers (e.g., calcium alkylbenzene sulfonate); ensure uniform dispersion of active ingredients Coatings/Inks Pigment Wetting and Dispersing Agent 0.5 ~ 3% (based on pigment weight) Add during the grinding stage to help reduce viscosity and prevent floating and flooding Metalworking Fluids Emulsifier, Lubricating Additive 1 ~ 5% Use with base oil and

Question 9

What industries and processes is Tween T-81 mainly used in?

Accepted Answer

Tween T-81 is widely used in over ten industries such as cosmetics, food, pharmaceuticals, pesticides, coatings, metal processing, and textiles, serving as a multifunctional nonionic surctant that plays key process roles including emulsification, solubilization, wetting, and dispersion. Detailed Description Tween T-81 (Polyoxyethylene (5) sorbitan monooleate, CAS No. 9005-65-6) is a well-balanced water-in-oil nonionic surctant, appearing as an amber oily liquid. With its unique molecular structure—grafting five polyoxyethylene chains and a monooleate group onto the sorbitan ring—it exhibits high efficiency, stability, and strong tolerance in various formulation systems, making it an indispensable functional auxiliary in multiple industrial fields. The core process value of this product lies in its "multi-functionality in one agent": it can serve as an efficient emulsifier to uniformly disperse oils and essential oils in the aqueous phase, as a solubilizer to significantly enhance the transparency and stability of poorly soluble substances, and as an excellent wetting and dispersing agent to rapidly reduce intercial tension and prevent solid particle agglomeration. Additionally, Tween T-81 remains active over a wide pH range, tolerating acidic, alkaline, and hard water environments, and when used in combination with the Span series, it allows flexible adjustment of the HLB value to achieve more precise emulsification. Major Application Industries and Processes Industry FieldSpecific Process/ProductFunctional Role Cosmetics and Personal CareCreams, lotions, makeup removers, bath oils, shampoos, body washesLipophilic emulsifier, solubilizer, emollient, providing fine texture and smooth skin feel Food IndustryIce cream, margarine, bakery productsFood-grade emulsifier and stabilizer, evenly dispersing oils, improving mouthfeel and shape retention Pharmaceutical PreparationsOral preparations, topical drug delivery systemsSolubilizer and emulsifier, promoting dissolution and dispersion of poorly soluble ingredients, enhancing bioavailability Pesticides and Agricultural AdjuvantsEmulsifiable concentrates, microemulsions, emulsion concentratesKey emulsifier, ensuring uniform dispersion of technical materials, enhancing wetting, spreading, and penetration of the spray liquid Coatings, Inks, and PigmentsPigment dispersion, coating preparationPigment wetting dispersant and emulsion stabilizer, preventing floating and flooding, improving gloss and adhesion Metalworking FluidsWater-based cutting fluids, grinding fluidsEmulsion stabilizer and boundary lubrication auxiliary, extending tool life, providing anti-rust auxiliary function Textile and Leather ProcessingSpinning oils, softening finishes, leveling agentsAntistatic, smoothing, and emulsifying effects, reducing fiber friction, improving bric hand feel Application Recommendations In actual formulation design, it is recommended to use Tween T-81 in combination with the Span series (e.g., Span 80). By adjusting the ratio of the two, the hydrophilic-lipophilic balance (HLB value) of the system can be precisely controlled, thereby adapting to the emulsification requirements of different oil phases. In pesticide microemulsions and cosmetic cream systems, the recommended dosage of Tween T-81 is typically 2% to 8% of the total formula weight. The specific dosage should be optimized through experiments based on the oil phase type and desired emulsion type (O/W or W/O). For transparent water-based products (e.g., makeup removers, body washes) that require solubilizing essential oils or fragrances, pre-mix Tween T-81 with the material to be solubilized at a ratio of 1:1 to 3:1, then slowly add water with dilution to obtain a clear and transparent solubilized system. Precautions Eye Irritation Risk: Tween T-81 is classified as GHS eye irritation Category 2 (H319). Always wear chemical safety goggles and protective gloves during handling. Storage Conditions: Store at temperatures between 5°C and 30°C, avoid freezing and overheating, keep the container tightly closed, and store in a cool, dry, well-ventilated area. Emergency Treatment: In case of eye contact, immediately rinse with plenty of water for at least 15 minutes. If wearing contact lenses, remove them and continue rinsing. If irritation persists, seek medical attention. Compounding Note: Store separately from incompatible substances such as strong oxidizers, and avoid operation at high temperatures or near open flames. The above information is sourced from the product database of Haian Guoli Chemical Co., Ltd. For more detailed technical parameters or to obtain samples, please feel free to contact our technical team.

Question 10

What are the physicochemical technical parameters of Tween T-81?

Accepted Answer

Tween T-81 is a nonionic water-in-oil emulsifier with an HLB value of 10, and its various physicochemical technical parameters are balanced and stable, suitable for formulation systems in multiple industries. Detailed Description Tween T-81 (Polyoxyethylene (5) Sorbitan Monooleate) is a classic nonionic surctant produced by Guoli Chemical, with the molecular formula C34H64O11 and a molecular weight of approximately 690. At room temperature, this product appears as a light yellow to amber oily liquid, characterized by low foaming and slight hygroscopicity. It is readily soluble in oils and organic solvents and can be dispersed in water. As a balanced performance emulsifier, Tween T-81, when used in combination with the Span series (sorbitan tty acid esters), can flexibly adjust the hydrophilic-lipophilic balance value of the system, achieving more precise emulsification effects. With excellent chemical stability, Tween T-81 can maintain its activity in mild acid, alkali, and hard water environments, making it widely applicable in industries such as cosmetics, food, pharmaceuticals, pesticides, coatings, and metalworking fluids. The following physicochemical technical parameters are sourced from the Guoli Chemical product database, providing an accurate basis for user formulation design and quality control. Technical Parameters Parameter ItemTechnical Indicator Product NameTween T-81 Chemical NamePolyoxyethylene (5) Sorbitan Monooleate CAS No.9005-65-6 AliasesPolysorbate 81, PEG-5 Sorbitan Monooleate, Tween 81 Molecular FormulaC34H64O11 Molecular WeightApprox. 690 Product TypeNonionic Surctant AppearanceLight yellow to amber oily liquid Active Content≥97% HLB Value10 Cloud Point (1% Aqueous Solution)50-60°C pH Value (1% Solution)5.0-7.0 pH Value (5% Solution)5.0-7.0 Density1.00-1.05 g\/cm³ Kinematic Viscosity (25°C)200-500 mm²\/s Refractive Index (20°C)1.470-1.480 Surce TensionApprox. 30-35 mN\/m Critical Micelle Concentration (CMC)0.01-0.1 g\/L Acid Value≤2 mgKOH\/g Saponification Value45-55 mgKOH\/g Hydroxyl Value65-85 mgKOH\/g Iodine Value18-25 gI2\/100g Moisture Content≤3.0% Flash Point>150°C HygroscopicitySlightly hygroscopic Foam PerformanceLow foaming Chemical StabilityStable at room temperature; stable under mild acid and alkali conditions SolubilityReadily soluble in oils and organic solvents, dispersible in water Heavy Metals≤10 mg\/kg Arsenic≤2 mg\/kg Packaging Specification50kg\/200kg plastic drum Application Recommendations Tween T-81 has an HLB value of 10, making it suitable as a transitional emulsifier for O\/W and W\/O emulsions, especially performing well in cosmetic creams, lotions, and makeup removers. It is recommended to be used in combination with the Span series (e.g., Span 80). By adjusting the ratio of the two, a composite emulsifying system with an HLB value ranging from 4 to 10 can be achieved, enabling more precise emulsification and stabilization effects. In pesticide emulsifiable concentrates and microemulsion formulations, the recommended dosage is typically 2% to 8% of the total formulation. In metalworking fluids, a recommended addition amount of 3% to 10% can significantly enhance emulsification stability and boundary lubrication performance. Precautions This product is classified under GHS as causing eye irritation (Category 2, H319). Always wear chemical safety goggles and protective gloves during handling. Store at temperatures between 5°C and 30°C, avoiding freezing and excessive heat; keep containers tightly sealed in a cool, dry, and well-ventilated place. In case of eye contact, immediately rinse with plenty of water for at least 15 minutes, and remove contact lenses if present; if irritation persists, seek medical attention immediately. Keep away from incompatible substances such as strong oxidizers. In case of spillage, collect using inert absorbent materials (e.g., diatomaceous earth, sand).

Tween T-81

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Property	Value
CAS No.	9005-65-6
Molecular Formula	C34H64O11
Appearance	Pale yellow to amber
Ionic Type	Nonionic
Avg. Molecular Weight	Approx. 690
Cloud Point	50-60°C (1%aq. soln.)
Active Content	≥97%
pH Value(1%)	5.0-7.0
pH Value(5%)	5.0-7.0
Iodine Value	18-25
Solubility	Readily soluble in oils and organic solvents; dispersible in water
Surface Tension	~30-35 mN/m
CMC	0.01-0.1 g/L
Acid Value	≤2
Saponification Value	45~55
Hydroxyl Value	65~85
Moisture	≤3.0
Density	1.00~1.05
Kinematic Viscosity	200-500 mm²/s (25°C)
Refractive Index	1.470-1.480 (20°C)
Flash Point	>150°C
Hygroscopicity	Slightly hygroscopic
Chemical Stability	Stable at room temperature
Foam Property	Low foam
Alkali Resistance	Stable under mild alkaline conditions
Solid Content	~100%
Heavy Metal	≤10 mg/kg
Arsenic	≤2 mg/kg

Tween T-81

Product Details

Applications

Properties

Safety

Product Overview

Performance Features

Packaging and Storage

Tween / Polysorbate Applications

Product Properties

Safety

GHS

Handling

Storage

First Aid

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