At room temperature, polyethylene glycol PEG-300 is a colorless to slightly yellow transparent viscous liquid with excellent solubility, moisture retention, and chemical stability. Its usage methods are flexible and varied; it can be used alone or miscible with various solvents such as water, alcohols, and glycerin in any proportion. According to different application scenarios, PEG-300 can be incorporated into the formulation system by stirring, heating (recommended to be controlled below 170°C), or direct addition.
In the pharmaceutical field, PEG-300 is commonly used as an ointment base and suppository base. It is usually heated to a molten state, mixed evenly with other drug ingredients, and then cooled to solidify. When used as a solvent for injections, strict aseptic procedures must be followed, and products meeting pharmaceutical-grade standards should be used. In daily chemical products, PEG-300 serves as a humectant and lubricant, generally added directly to the formula during the emulsification or stirring stage, with a recommended addition amount of 2% to 10% (depending on the specific formulation).
In industrial applications, PEG-300 can be used as a solvent and plasticizer for coatings and inks. It is recommended to be added during the grinding or dispersion stage to improve the leveling and stability of the product. In the agricultural field, when used as a pesticide emulsifier and spreading agent, it is usually compounded with pesticide technical materials and other auxiliaries, then diluted and sprayed. In rubber processing, PEG-300 serves as a component of mold release agents or a dispersion medium for vulcanization accelerators, and can be directly coated on the mold surface or mixed into the rubber compound.
| Parameter | Value/Description |
|---|---|
| Ion type | Nonionic |
| Appearance | Colorless to slightly yellow transparent viscous liquid |
| Solubility | Miscible with various solvents such as water, alcohols, and glycerin in any proportion |
| Recommended operating temperature | Controlled within a safe range below 170°C |
| Flash point (closed cup) | 195°C ~ 234°C |
| Hygroscopicity | Has certain hygroscopicity; needs to be sealed promptly after opening |
Pharmaceutical Preparations: When used as an ointment base, heat to about 60~70°C to make it flowable, mix evenly with the drug, then cool and solidify. When used as a solvent for injections, the dosage must comply with drug registration standards and should be operated under GMP conditions. This product has good biocompatibility, with an acute oral toxicity LD50 > 20 g/kg, belonging to the practically non-toxic grade.
Daily Chemical Products: It is recommended to be added during the emulsification stage, with a recommended addition amount of 2%~10% of the formula. It can be compounded with humectants such as glycerin and propylene glycol to enhance the product's moisturizing feel and application smoothness. Suitable for creams, lotions, shampoos, toothpaste, and other products.
Coatings and Inks: As a plasticizer and solvent, it is recommended to be added during the pigment dispersion stage, accounting for 1%~5% of the total formula. It can improve the flexibility and adhesion of the coating film and enhance leveling.
Pesticide Formulations: When preparing, compound with pesticide technical material and emulsifier according to the recommended ratio, then dilute and use as a spray liquid. It can enhance the wetting and spreading ability of the spray liquid on plant leaves.
Rubber Processing: When used as a mold release agent, it can be directly coated on the inner wall of the mold. When used as a dispersion medium for vulcanization accelerators, add during the mixing stage, with a recommended dosage of 0.5%~3% of the rubber mass.