Compared to other molecular weights of polyethylene glycol (such as PEG-200, PEG-400, PEG-600, etc.) and traditional organic solvents or surfactants, the polyethylene glycol PEG-300 produced by Guoli Chemical achieves a more delicate balance between safety and functionality. Its core advantage is first reflected in an extremely high safety margin: the acute oral toxicity LD50 > 20 g/kg, which is practically non-toxic, and it is non-irritating to the skin, non-sensitizing, and non-genotoxic. This means it can be safely used in fields with extremely strict requirements for purity and biocompatibility, such as pharmaceutical injections, topical ointments, and high-end personal care products, which many industrial-grade solvents or ionic surfactants cannot match.
In terms of application breadth, PEG-300 demonstrates multifunctionality as "one agent, multiple uses." It is an efficient emulsifier, solubilizer, and dispersant, and due to its moderate molecular weight (285~315), it combines low volatility with good fluidity, allowing it to be used alone as a plasticizer, humectant, and lubricant. Compared to lower molecular weight PEG (higher volatility, insufficient moisture retention) or higher molecular weight PEG (excessive viscosity, inconvenient operation), PEG-300 is a transparent viscous liquid at room temperature (with a freezing point as low as -15~-8°C), ensuring long-term formulation stability while facilitating pumping and metering. This greatly simplifies the process in coatings, inks, textiles, and pesticide formulation processing.
Furthermore, the environmental friendliness of PEG-300 constitutes a key competitive advantage. Its characteristics of easy biodegradability and no bioaccumulation align with the global trend toward green chemical products. Additionally, its non-ionic nature allows it to maintain stable chemical performance over a wide pH range and in hard water conditions, with excellent compatibility with most components in formulations except acids, bases, and oxidizing agents. This significantly reduces the risk of formulation failure due to incompatibility, ensuring the quality and batch consistency of downstream products from the raw material side.
| Parameter Category | Item | Guoli Chemical PEG-300 Typical Value | Advantage Explanation |
|---|---|---|---|
| Basic Physical Properties | Appearance | Colorless to slightly yellow transparent liquid | High purity, meeting pharmaceutical-grade sensory requirements |
| Average Molecular Weight | 285 ~ 315 | Balances fluidity and low volatility | |
| Viscosity (40°C) | 60 ~ 75 mm²/s | Moderate, easy for transport and processing | |
| Freezing Point | -15 ~ -8°C | Better low-temperature fluidity than PEG-400, etc. | |
| Functional Indicators | HLB Value | Approx. 16.5 | Strong hydrophilicity, excellent O/W emulsification and solubilization |
| Hydroxyl Value (mgKOH/g) | 356 ~ 394 | High reactivity, easy for derivatization modification | |
| Cloud Point (1% Aqueous Solution) | > 100°C | Good high-temperature stability, no precipitation | |
| Safety and Environmental Protection | Acute Oral LD50 | > 20 g/kg (Practically Non-toxic) | Pharmaceutical-grade safety level |
| Flash Point (Closed Cup) | > 200°C | Non-flammable, safe for storage and transport | |
| Biodegradability | Readily Biodegradable | Meets OECD standards, low environmental burden | |
| Heavy Metals/Arsenic | ≤ 10 mg/kg / ≤ 2 mg/kg | Low impurities, meeting strict regulations |
First Choice for Pharmaceuticals: With its practically non-toxic grade and excellent biocompatibility, PEG-300 is an ideal choice for ointment bases, suppository carriers, pill matrices, and injection solvents. Its non-irritating and non-sensitizing properties to the skin make it especially suitable for pediatric and sensitive skin formulations.
High-End Daily Chemical Moisturizing: In serums, creams, and toothpaste, the recommended addition amount is 2%~10% of the total formulation. Utilizing its dual function of moisture absorption and lubrication, it effectively improves the product's smooth application and post-application moisturizing feeling, with good low-temperature formulation stability.
Green Industrial Alternatives: In coatings and inks, it serves as an environmentally friendly plasticizer and solvent, replacing traditional phthalates. The recommended dosage is 5%~15% of the resin solid content, significantly reducing VOC emissions while improving coating film flexibility. In pesticide formulations, it acts as an emulsifying spreading agent, enhancing the wetting and spreading of the spray liquid on hydrophobic leaf surfaces, thereby improving efficacy utilization.
Rubber Processing Additive: As an internal mold release agent and dispersion medium for vulcanization accelerators, it is recommended to add 0.5%~2% during the mixing stage. Its moderate viscosity helps achieve uniform dispersion in the rubber matrix and is not easily volatilized, ensuring process stability during continuous production.