Question

In which industries and processes is polyethylene glycol PEG-300 mainly used?

Answer
2026-06-06 官方文档 聚乙二醇PEG-300

Polyethylene glycol PEG-300 is widely used in five core fields: pharmaceuticals, daily chemicals, industrial manufacturing, rubber processing, and agriculture. It is a multifunctional nonionic solvent, humectant, and processing aid.

Detailed Description

Polyethylene glycol PEG-300 (CAS No.: 25322-68-3) is a nonionic surfactant produced by Guoli Chemical, appearing as a colorless to slightly yellow transparent viscous liquid. With its excellent emulsifying, wetting, dispersing, and solubilizing capabilities, as well as outstanding chemical stability (resistant to acids, bases, and hard water conditions), this product has become a key functional additive in multi-industry process steps.

In the pharmaceutical industry, PEG-300 is widely used as a water-soluble ointment base, suppository base, pill carrier, and injection solvent due to its good biocompatibility and low toxicity. It is also used in tablet coating and lubrication. In the daily chemical industry, as an efficient humectant, lubricant, and surfactant intermediate, it is extensively added to personal care products such as skin care products, shampoos, and toothpaste, significantly enhancing the moisturizing feel and user experience.

In the industrial sector, PEG-300 has diverse applications: it provides lubrication and antistatic treatment in papermaking and textile processing; it is used as a solvent and plasticizer in coatings and inks to improve leveling and stability; in rubber products, it acts as an effective component of mold release agents and a dispersing medium for vulcanization accelerators; in agriculture, it is used as a pesticide emulsifier and spreader to enhance the wetting and spreading ability of the spray liquid on plant surfaces, thereby improving pesticide application efficacy.

Technical Parameters

Parameter ItemParameter Value
Ion TypeNonionic
AppearanceColorless to slightly yellow transparent viscous liquid
CAS No.25322-68-3
Flash Point (Closed Cup)195℃~234℃
Autoignition TemperatureApproximately 310℃~350℃
Hazard ClassificationNon-hazardous
Skin IrritationNon-irritating
BiodegradabilityReadily biodegradable (meets OECD standards)

Application Recommendations

Pharmaceutical Processes: When used as an injection solvent or ointment base, it is recommended to be used in a clean environment and ensure sealed storage to prevent moisture absorption. For tablet coating, its plasticizing properties can be utilized to adjust the flexibility of the coating material.

Daily Chemical Formulations: It is recommended to add it to creams, lotions, shampoos, and other formulations as a moisturizing and lubricating component. The reference dosage should be adjusted according to the formulation system, generally suggested in the range of 1% to 10%. Its nonionic nature provides good compatibility with anionic, cationic, and amphoteric surfactants.

Industrial Lubrication and Plasticization: In textile processing, it can be used for antistatic treatment of yarns or fibers. In coating and ink systems, it is recommended to be added during the paint mixing stage to improve application performance due to its low volatility and good solubility.

Rubber Processing: As a component of mold release agents or a dispersing medium for vulcanization accelerators, it can improve dispersion uniformity and reduce surface defects of products.

Pesticide Formulations: Used as an emulsifier and spreader, it effectively reduces the surface tension of the spray liquid, enhances the spreading and adhesion ability on leaves, and improves the utilization rate of pesticide efficacy.

Precautions

  • Hygroscopicity: PEG-300 is hygroscopic. After opening, reseal it as soon as possible to avoid prolonged exposure to humid air, which may affect product quality.
  • Operating Temperature: It is recommended to control the operating temperature below 170℃, staying away from the flash point (195℃). Ensure good ventilation when heating.
  • Incompatible Materials: Avoid contact with strong oxidizing agents (such as peroxides, permanganates, concentrated nitric acid, etc.) to prevent hazardous reactions.
  • Storage Conditions: Recommended storage temperature is 5℃ to 40℃. Use stainless steel or polyethylene (HDPE/LDPE) containers sealed and stored away from open flames and heat sources.
  • Safety Protection: Although this product is non-irritating to the skin and not classified as hazardous, it is still recommended to wear protective gloves and chemical safety goggles during operation, and thoroughly wash hands after use.