Polyethylene Glycol PEG-300 (CAS No.: 25322-68-3) is a non-ionic surfactant produced by Guoli Chemical, appearing as a colorless to slightly yellow transparent viscous liquid, almost odorless. Its chemical structure is α-hydro-ω-hydroxy polyethylene glycol, with an average molecular weight of about 300, belonging to the low molecular weight polyethylene glycol series. This product is synthesized through the stepwise addition polymerization of ethylene oxide with water or ethylene glycol, and its molecular chain contains numerous ether bonds and terminal hydroxyl groups, granting it excellent hydrophilicity and chemical stability.
PEG-300 exhibits outstanding multifunctional characteristics: excellent emulsifying ability, effectively reducing oil-water interfacial tension to uniformly mix immiscible phases; superior wetting and dispersing properties, promoting uniform distribution of solid particles in liquid media; significant solubilization effect, increasing the solubility of poorly soluble substances in water. At the same time, the product is chemically stable, maintaining good performance in acidic, alkaline, and hard water environments, and has low volatility, ensuring long-lasting lubrication and moisturizing effects.
In terms of safety, PEG-300 is classified as a practically non-toxic substance, with an acute oral LD50 greater than 20 g/kg, non-irritating to the skin, non-sensitizing, and negative for genotoxicity and carcinogenicity assessments. It has good biodegradability, meeting OECD rapid biodegradation standards, and is essentially non-toxic to aquatic organisms, making it an environmentally friendly product.
| Parameter | Technical Indicator |
|---|---|
| Product Name | Polyethylene Glycol PEG-300 |
| CAS No. | 25322-68-3 |
| Aliases | PEG-300, Polyethylene Glycol 300, Macrogol 300, Polyoxyethylene Glycol 300 |
| Ion Type | Non-ionic |
| Appearance | Colorless to slightly yellow transparent viscous liquid |
| Flash Point (Closed Cup) | 195℃～234℃ |
| Autoignition Temperature | Approximately 310℃～350℃ |
| Acute Oral Toxicity (LD50) | > 20 g/kg (Practically non-toxic) |
| Skin Irritation | Non-irritating |
| Sensitization | None |
| Biodegradability | Readily biodegradable (Meets OECD standards) |
| Hazard Classification | Non-hazardous |
| Recommended Storage Temperature | 5℃～40℃ |
| Maximum Operating Temperature | Recommended below 170℃ |
Pharmaceutical Industry: PEG-300 is an important excipient in the pharmaceutical field, used as a water-soluble ointment base, suppository base, drop pill carrier, and injection solvent, as well as a tablet coating and lubricant. Its good biocompatibility and low toxicity make it an indispensable functional excipient in pharmaceutical formulations.
Daily Chemical Industry: As a highly effective moisturizer and lubricant, PEG-300 is widely added to personal care products such as skincare products, shampoos, and toothpaste, effectively improving the moisturizing feel and user experience. It is also a crucial intermediate for synthesizing other surfactants.
Industrial Applications: Provides lubrication and antistatic treatment in papermaking and textile processing; used as a solvent and plasticizer for coatings and inks, improving product leveling and stability; serves as an effective component of mold release agents and a dispersing medium for vulcanization accelerators in rubber products.
Agricultural Field: Used as a pesticide emulsifier and spreader, enhancing the wetting and spreading ability of the spray liquid on plant surfaces, significantly improving pesticide application effectiveness and utilization.