Polyethylene Glycol 400 Dioleate (PEG400DO) is a nonionic surfactant with relatively high safety. Its acute oral toxicity LD50 is greater than 5000 mg/kg (rats), classifying it as a low-toxicity substance. However, the product is still classified as Skin Irritant (Category 2), Eye Irritant (Category 2), and Specific Target Organ Toxicity - Single Exposure (Category 3, respiratory tract irritation). Therefore, its potential irritation risks should not be overlooked during industrial operations and formulation processes.
This product is readily biodegradable and has a low cumulative impact on the environment. However, it may still cause harmful effects to aquatic organisms in the short term. Waste liquids containing this ingredient should not be directly discharged into natural water bodies. Under normal storage conditions, PEG400DO is chemically stable, but it is recommended to store it in a cool, dry, well-ventilated place away from strong oxidizers and ignition sources. Keep the container sealed to avoid moisture absorption and deterioration.
As a nonionic surfactant, PEG400DO has good compatibility with anionic, cationic, and other nonionic surfactants, allowing flexible combinations in compounding. However, it is recommended to conduct small-scale tests before mass production to confirm compatibility with other components and the stability of the final formulation.
| Item | Requirement |
|---|---|
| Personal Protective Equipment (PPE) | Wear protective gloves, protective clothing, protective goggles/face shield to avoid direct skin and eye contact |
| Respiratory Protection | Avoid inhalation of dust/fumes/gas/mist/vapors/spray (P261). Use a respirator in poorly ventilated areas |
| Workplace Hygiene | Thoroughly wash exposed skin after handling (P264). Launder work clothing regularly, do not take it home |
| Eye Contact Treatment | Immediately rinse cautiously with water for several minutes; remove contact lenses if present and easy to do, then continue rinsing (P305+P351+P338) |
| Persistent Eye Irritation | If eye irritation persists after rinsing, seek medical attention immediately (P337+P313) |
| Storage Conditions | Store in a cool, dry, well-ventilated place. Keep container tightly closed, away from strong oxidizers |
| Waste Disposal | Dispose of in accordance with local regulations; do not discharge into water bodies or soil directly |
The above suggestions are for process reference only. In actual use, optimization and adjustment should be made based on the specific formulation system, processing conditions, and target product performance requirements. When using for the first time or changing batches, it is recommended to conduct small-scale tests to confirm process suitability and product safety before scaling up production.