PEG400DO (Polyethylene Glycol 400 Dioleate) is a low-toxicity nonionic surfactant with an acute oral toxicity LD50 > 5000 mg/kg (rat), indicating overall low toxicity. However, according to the Guoli Chemical product safety data, this product is still classified by GHS as Skin irritation (Category 2), Eye irritation (Category 2), and Specific target organ toxicity - single exposure (Category 3, respiratory irritation). Therefore, adequate attention must be given during handling and use.
In actual use, PEG400DO is a light yellow to amber liquid with a flash point above 200°C. Vapor volatilization is low at room temperature, but during heating, stirring, or spraying operations, mists or vapors may be generated, which can cause respiratory discomfort if inhaled. Its ester bond structure is prone to hydrolysis under alkaline conditions, so it should avoid being mixed, stored, or used with strong alkaline substances to prevent additional risks from decomposition products.
| Item | Content |
|---|---|
| GHS Classification | Skin irritation (Category 2); Eye irritation (Category 2); Specific target organ toxicity - single exposure (Category 3, respiratory irritation) |
| Hazard Statements | H315: Causes skin irritation / H319: Causes serious eye irritation / H335: May cause respiratory irritation |
| Precautionary Measures | P261: Avoid breathing dust/fume/gas/vapor/spray P280: Wear protective gloves/protective clothing/eye protection/face protection |
| Post-work Requirements | P264: Wash thoroughly after handling |
| Eye First Aid | P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing P337+P313: If eye irritation persists: Get medical advice/attention |
| Acute Toxicity (Oral) | LD50 > 5000 mg/kg (rat) |
When using PEG400DO in scenarios such as textile oil compounding, metalworking fluid formulation, personal care product manufacturing, and pesticide formulation processing, it is recommended to operate in a well-ventilated environment. If heating for melting or prolonged stirring is required, activate local exhaust ventilation to reduce accumulation of vapors or mists in the air. The product is a low-foaming surfactant, not prone to generating excessive foam during stirring, but attention should still be paid to splashing risks.