Polypropylene glycol PPG-400 (also known as polyoxypropylene glycol, polypropylene oxide, Polypropylene glycol 400) is a linear polymer with propylene oxide as the core monomer and a molecular weight of approximately 400. The ether bonds in its molecular structure endow the product with good flexibility and chemical stability, while the terminal hydroxyl groups provide reactive sites for further chemical modification. Produced by Hai'an Guoli Chemical Co., Ltd., this product plays a key role as an intermediate and functional component in many industrial formulations due to its low hygroscopicity, high compatibility, and low toxicity.
The most notable feature of PPG-400 is its excellent surface activity and chemical inertness—it maintains stable physicochemical properties in acidic, alkaline, and hard water media, and is not prone to hydrolysis or failure. At the same time, the product has a high primary hydroxyl content and moderate reactivity, making it a high-quality raw material for synthesizing polyurethanes, ester derivatives, and more. In terms of safety, PPG-400 has low acute oral toxicity (rat oral LD₅₀ > 2000 mg/kg), is non-irritating to the skin, causes only slight and transient eye irritation, and is non-sensitizing, allowing it to meet high safety standards in personal care and pharmaceutical fields.
As a versatile chemical intermediate, PPG-400 serves as a soft segment component in the polyurethane industry, effectively adjusting the flexibility and hydrolysis resistance of materials; in lubricants, it serves as an important raw material for synthetic ester base oils due to its excellent viscosity-temperature characteristics and thermal stability; in daily chemicals, it acts as a humectant, solubilizer, and skin feel enhancer, helping to uniformly disperse active ingredients.
| Parameter | Value |
|---|---|
| Product Name | Polypropylene glycol PPG-400 |
| CAS Number | 25322-69-4 |
| Aliases | Polyoxypropylene glycol, Polypropylene oxide, PPG 400, Polypropylene glycol 400, PAG 400 |
| Appearance | Colorless to slightly yellow transparent viscous liquid |
| Molecular Weight | Approximately 400 |
| Type | Nonionic surfactant |
| Flash Point (Closed Cup) | Approximately 220–230°C |
| Solubility | Excellent compatibility with various organic solvents, resins, and polymers |
| Acute Toxicity (Rat Oral) | LD₅₀ > 2000 mg/kg (low toxicity) |
| Skin Irritation | Non-irritating (New Zealand White Rabbit test) |
| Eye Irritation | Slight, transient irritation (Draize score ≤2, recovery within 24 hours) |
| Sensitization | Non-sensitizing (Guinea pig closed patch test negative) |
| Biodegradability | Not readily biodegradable (OECD 301B, degradation rate ≤20% in 28 days) |
| Aquatic Toxicity | Fish, Daphnia, Algae L(E)C₅₀ all >100 mg/L (low toxicity) |
| Recommended Storage Temperature | 0–40°C |
| Shelf Life | Not less than 12 months (in original sealed container at appropriate temperature) |
| Packaging | Clean and dry galvanized iron drums or ton drums |
Note: Some parameters such as hydroxyl value, viscosity, density, pH, etc., are not precisely available. Please contact Guoli Chemical for a detailed Certificate of Analysis (COA).
Polyurethane Industry: Used as a key polyol soft segment component in flexible and rigid polyurethane foams, elastomers, coatings, and adhesives. Recommended for polyurethane product formulations requiring flexibility and hydrolysis resistance, effectively adjusting chain segment flexibility and hydrophilic-hydrophobic balance.
Lubricants and Functional Fluids: Used as a base oil or co-solvent in synthetic high-temperature lubricants, hydraulic fluids, compressor oils, and metalworking fluids, providing excellent lubricity, cleanliness, and antioxidant synergy, suitable for use over a wide temperature range.
Surfactants and Emulsifiers: As a nonionic surfactant intermediate, widely used in industrial cleaning, textile auxiliaries (e.g., synthetic fiber oils), etc., performing emulsifying and dispersing functions.
Personal Care and Cosmetics: Used as a humectant, lubricant, and solubilizer in creams, lotions, and facial cleansers, improving skin feel and helping to uniformly disperse active ingredients, with dosage adjusted according to specific formulations.
Pharmaceutical Applications: Can be used as a suppository base, ointment base, and drug solubilizer, with safety meeting relevant pharmaceutical requirements.
Other Industrial Uses: Can serve as a defoamer raw material, mold release agent component, heat transfer fluid, etc., meeting various industrial processing needs.