Stearic acid polyoxyethylene ether SG-10 (CAS No.: 9004-99-3) is a classic fatty acid polyoxyethylene ester nonionic surfactant. Its molecular structure consists of hydrophilic polyoxyethylene chains and lipophilic stearate groups. This structure endows the product with excellent surface activity and also determines its mild safety profile. The product is widely used in cosmetics, personal care products, textile printing and dyeing auxiliaries, and other fields that come into direct or indirect contact with the human body, fully demonstrating its safety and reliability.
From the perspective of human health effects, the product has extremely low acute oral toxicity (rat LD50 > 5,000 mg/kg), classifying it as low-toxicity, and poses no health risk at actual usage levels. Skin irritation tests show that a 5% dilution is non-irritating to rabbit skin (Primary Irritation Index PII 0–0.5), making it suitable for formulations that come into direct contact with skin. Regarding eyes, the pure product only causes slight reversible irritation and is not classified as a serious eye damage substance. Skin sensitization tests (guinea pig Buehler test) were negative, with no sensitization observed. In terms of genotoxicity, the Ames test and in vitro mammalian cell chromosome aberration test were both negative, indicating no genotoxicity.
In terms of environmental impact, the product has a fish acute toxicity of 96-hour LC50 > 100 mg/L, indicating low toxicity to aquatic organisms. More importantly, under OECD 301B test conditions, its 28-day biodegradation rate exceeds 60%, making it a readily biodegradable substance that can be effectively degraded in conventional wastewater treatment systems without accumulating in the environment. The product complies with environmental regulatory requirements, but care should still be taken to avoid large-scale discharge into water bodies, soil, or sewers to prevent local short-term accumulation.
| Test Item | Test Subject/Method | Result | Conclusion |
|---|---|---|---|
| Acute Oral Toxicity | Rat | LD50 > 5,000 mg/kg | Low toxicity |
| Skin Irritation | Rabbit (5% dilution) | PII 0–0.5 | Non-irritating |
| Eye Irritation | Rabbit (pure product) | Slight irritation | Reversible irritation |
| Skin Sensitization | Guinea pig (Buehler test) | Negative | No sensitization |
| Genotoxicity (Ames test) | In vitro | Negative | No genotoxicity |
| Chromosome Aberration Test | In vitro mammalian cells | Negative | No genotoxicity |
| Fish Acute Toxicity | 96-hour LC50 | > 100 mg/L | Low aquatic toxicity |
| Biodegradability | OECD 301B (28 days) | Degradation rate > 60% | Readily biodegradable |
Based on the above safety data, this product has high safety for use in various application fields: