Question

What is Polypropylene Glycol PPG-600? What are its main uses?

Answer
2026-06-06 官方文档 聚丙二醇PPG-600

Polypropylene Glycol PPG-600 (CAS No.: 25322-69-4) is a non-ionic polymer of propylene oxide, appearing as a colorless to slightly yellow transparent viscous liquid. It is widely used in various fields such as polyurethane synthesis, industrial defoamers, lubricants, daily chemicals, and pharmaceuticals.

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Detailed Description

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Polypropylene Glycol PPG-600, also known as PPG-600, polyoxypropylene glycol, or polypropylene glycol polyether, is a high-molecular-weight polymer formed by the ring-opening polymerization of propylene oxide. It belongs to the category of non-ionic surfactants. The molecular structure contains multiple ether bonds and terminal hydroxyl groups, giving it excellent emulsifying and dispersing properties, wetting and solubilizing capabilities, as well as good chemical stability.

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This product exhibits excellent resistance to acids, alkalis, and hard water, maintaining stable performance under a wide range of pH conditions and in hard water environments. Additionally, its low volatility and high flash point (>200°C, closed cup) ensure operational safety, making it suitable for high-temperature processes. As a non-ionic product, it has good compatibility with anionic, cationic, and amphoteric surfactants, offering high flexibility for formulation.

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In terms of safety, PPG-600 is not classified as a hazardous substance. It has low acute oral toxicity (LD₅₀ > 2,000 mg\/kg) and is non-irritating to the skin. It is considered a low-toxicity substance with no significant hazards to human health under normal use conditions.

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Technical Parameters

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Parameter ItemParameter Value
Product NamePolypropylene Glycol PPG-600
CAS No.25322-69-4
Product TypeNon-ionic Surfactant \/ Polyether Polyol
AppearanceColorless to slightly yellow transparent viscous liquid
Ionic TypeNon-ionic
Flash Point (Closed Cup)> 200 °C
Acute Toxicity (Oral, Rat)LD₅₀ > 2,000 mg\/kg
Skin IrritationNon-irritating
GHS ClassificationNot classified as hazardous substance or mixture
Resistance to Acids, Alkalis, and Hard WaterExcellent, stable under wide pH range
Recommended Storage Temperature5 °C to 40 °C
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Application Suggestions

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Polyurethane Industry: As a core component of polyether polyols, it reacts with isocyanates to form prepolymers, imparting excellent flexibility, resilience, and hydrolysis resistance to the finished products. It is an important synthetic raw material for polyurethane prepolymers and elastomers.

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Industrial Additives and Functional Fluids: Utilizing its low surface tension and good dispersibility, it can be used as a base component for industrial defoamers (suitable for fermentation, papermaking, coatings, etc.); in mold release agents, it forms an effective separation film for smooth demolding; it can also be used as a plasticizer and softener to increase material flexibility.

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Lubricants and Metalworking Fluids: As a synthetic lubricant base oil, it offers excellent lubricity and thermal-oxidative stability; in water-glycol fire-resistant hydraulic fluids, it provides thickening and lubricating effects; in metal cutting fluids and quenchants, it offers good lubrication and cooling performance.

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Daily Chemicals and Pharmaceuticals: It can be used as a solvent, humectant, and skin feel modifier in cosmetics; by further etherification or esterification reactions, it can produce non-ionic surfactants; in the pharmaceutical field, it serves as a water-soluble base material for ointments and suppositories, exhibiting good biocompatibility.

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Precautions

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  • Eye contact may cause mild discomfort (e.g., redness, tearing). It is recommended to wear chemical safety goggles during operation.
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  • Keep away from open flames in high-temperature environments, ensure good ventilation; install local exhaust ventilation in processes involving heating or aerosol generation.
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  • It is recommended to wear chemically resistant protective gloves (e.g., nitrile or neoprene gloves).
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  • Store in a cool, dry, well-ventilated place away from extreme temperature fluctuations, and keep away from strong oxidizers and strong acids.
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  • Low temperatures may increase viscosity or cause solidification; warm to room temperature and stir evenly before use.
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  • Avoid direct discharge into water bodies. Dispose of waste in accordance with local regulations; incineration in approved facilities is recommended.
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