Question 1

Is polypropylene glycol PPG-600 harmful to the human body? Does it have an impact on the environment?

Accepted Answer

Polypropylene glycol PPG-600 is a low-toxicity substance and has no significant harm to human health under normal use conditions; it has low aquatic toxicity and is not easily bioaccumulated in the environment, but direct discharge into water bodies should be avoided. Detailed Description Impact on Human Health According to the safety data from the Guoli Chemical Product Database, polypropylene glycol PPG-600 is not classified as a dangerous substance under GHS classification. Its acute oral toxicity LD₅₀ is greater than 2,000 mg\/kg (rat), indicating low toxicity. In terms of skin irritation, this product is non-irritating, but prolonged or repeated contact may cause skin detting; it is recommended to wear nitrile or neoprene gloves during operation. Eye contact may cause mild discomfort, such as redness and tearing, and it is advised to wear chemical safety goggles. Under normal use conditions, it has no significant harm to human health, but inhalation of oil mist or vapor should be avoided, and hands should be thoroughly washed after operation. Impact on the Environment Polypropylene glycol PPG-600 has low aquatic toxicity and is not easily bioaccumulated, making it an environmentally friendly chemical. However, large amounts of untreated product directly discharged into water bodies may still adversely affect aquatic ecosystems. According to the product safety instructions, effective measures should be taken during use to prevent leaks from entering sewers, surce water, or groundwater. Waste disposal should comply with local regulations, and it is recommended to incinerate or recycle at qualified waste treatment cilities; direct discharge into water bodies or soil is strictly prohibited. Technical Parameters Safety-Related Technical Indicators (Data Source: Guoli Chemical Database) Parameter ItemValue\/Description GHS ClassificationNot classified as a dangerous substance Acute Toxicity (Oral, Rat)LD₅₀ > 2,000 mg\/kg (low toxicity) Skin IrritationNon-irritating Eye IrritationMay cause mild discomfort Flash Point (Closed Cup)> 200 ℃ (not flammable at normal operating temperatures) Aquatic ToxicityLow aquatic toxicity BioaccumulationNot easily bioaccumulated Transport ClassificationNot classified as dangerous goods Heavy Metal Content≤10 mg\/kg Arsenic Content≤2 mg\/kg Application Recommendations Given the low toxicity and good biocompatibility of polypropylene glycol PPG-600, it is widely used in fields that involve direct or indirect contact with the human body, such as cosmetics and pharmaceuticals: Cosmetics Field: Can be used as a solvent, humectant, and skin feel modifier, with mild skin-friendly properties Pharmaceutical Field: Can be used as a water-soluble base material for ointments and suppositories, with good drug release performance Industrial Field: Used as a raw material for polyurethane synthesis, defoamer, base oil for lubricants, metalworking fluids, etc., safe and controllable under normal industrial operating conditions Precautions Maintain good ventilation during operation; processes involving heating or generating aerosols should be equipped with local exhaust ventilation Store in a cool, dry, well-ventilated place, recommended temperature 5°C to 40°C, away from strong oxidizers and strong acids In case of large spills, contain with inert absorbent material to prevent entry into water bodies; combustion may produce toxic fumes such as carbon monoxide; firefighters should wear self-contained positive-pressure breathing apparatus Waste disposal must comply with local regulations; incineration or recycling recommended; direct discharge into the environment is prohibited The above data is based on the Guoli Chemical Product Database and the product safety data sheet; please refer to the complete MSDS for specific use

Question 2

What should I do if problems occur during the use of polypropylene glycol PPG-600? How can I obtain technical support?

Accepted Answer

If problems occur during the use of polypropylene glycol PPG-600, it is recommended to first conduct common ult troubleshooting based on product characteristics. If the issue cannot be resolved, contact Haian Guoli Chemical Co., Ltd. for professional technical support. Detailed Description Polypropylene glycol PPG-600 is a non-ionic polypropylene oxide polymer with stable chemical properties and wide compatibility, rarely causing serious problems under normal use conditions. If anomalies occur during use, they are usually related to ctors such as storage conditions, operating procedures, formulation compatibility, or contamination by impurities. It is recommended to follow the approach of "self-check first, then consult" for step-by-step troubleshooting. Most issues can be resolved by adjusting operating conditions. Guoli Chemical provides Safety Data Sheets (SDS) and Technical Data Sheets (TDS) for all products, which contain detailed operating specifications, emergency response measures, and technical parameters. When users encounter issues during use, they can first refer to these documents for immediate guidance. If the problem remains unresolved, the technical team at Guoli Chemical can provide one-on-one technical consultation services. Common Issues and Troubleshooting Directions Common Issue Possible Cause Recommended Action Turbidity, layering, or precipitation in the product Long-term low-temperature storage leading to increased viscosity or partial solidification; or moisture absorption during storage Heat the product to 20°C~40°C and stir thoroughly before use; check container sealing to avoid prolonged exposure to humid air Abnormal increase in product viscosity Storage temperature too low (below 5°C); or product exceeds recommended storage period Allow natural temperature recovery in a room-temperature environment; if necessary, use a warm water bath (not exceeding 40°C) to heat and stir until uniform; confirm production date and shelf life of the product Incompatibility or precipitation during compounding Mixing with strong acids, strong oxidizers, or incompatible systems; pH conditions too extreme PPG-600 is non-ionic and should be compatible with anionic, cationic, or amphoteric surctants; check for strong oxidizers or strong acids in the formulation; adjust the formulation pH to neutral or slightly acidic/alkaline range Abnormal polyurethane synthesis reaction (e.g., reaction too st/slow, product performance not meeting standards) Excessive moisture content in raw materials; improper isocyanate ratio; incorrect reaction temperature control Dehydrate PPG-600 before use (vacuum heating dehydration); accurately calculate and control the isocyanate index; strictly control the reaction temperature according to process requirements Poor defoaming performance Insufficient dosage; pH or temperature of the system beyond applicable range; improper dispersion method Optimize dosage and ensure thorough dispersion; PPG-600 is stable under a wide pH range, but extreme conditions require verification; adjust the timing of addition and stirring conditions Product color darkening Trace oxidation due to high temperature or long-term storage; incompatible container material Check if storage temperature exceeds 40°C, avoid prolonged high temperatures; ensure use of stainless steel, carbon steel, or polypropylene containers, avoid incompatible materials Ways to Obtain Technical Support If the problem remains unresolved after the above troubleshooting, you can contact Haian Guoli Chemical Co., Ltd. via the following methods for professional technical support: Consult SDS/TDS documents: The Safety Data Sheet and Technical Data Sheet provided with the product contain detailed technical parameters, operating guidelines, and emergency response measures, serving as primary reference materials for problem resolution. Contact Sales Manager: Communicate directly with your dedicated sales consultant or contact person, providing the product batch number, usage conditions, and specific anomalies for quick problem identification. Official Website Technical Inquiry: Visit the official website of Guoli Chemical and submit your issue through online customer service or the technical support portal. Technical engineers will provide targeted advice based on your application scenario. Sample Submission for Analysis: If the issue involves product quality disputes, you can send a sample to Guoli Chemical's quality inspection department for re-testing and analysis to obtain an authoritative test report. Information to Prepare When Communicating with Technical Support To help technical personnel efficiently diagnose the issue, it is recommended to prepare the following information in advance: Product batch number/production date (see packaging label) Storage conditions (temperature, humidity, container material, time since opening) Specific application scenario (e.g., polyurethane synthesis, defoamer compounding, cosmetic formulation, etc.) Description of anomalies (time of occurrence, appearance changes, performance deviations, etc.) Operating process parameters (temperature, dosage, compounding ingredients, stirring conditions, etc.) Notes For issues involving personal safety (e.g., ingestion, large spill, eye contact), immediately follow the first aid measures and emergency procedures in the product's SDS, seek medical attention or contact the fire department, and then contact Guoli Chemical. Before using the product, ensure that the complete Safety Data Sheet (SDS) is read to ensure all operators are aware of the safety precautions. PPG-600 is classified as a non-hazardous substance (GHS classification) and poses no significant health risks under normal use, but it is still recommended to wear appropriate eye protection and protective gloves.

Question 3

How to purchase polypropylene glycol PPG-600? What is the minimum order quantity?

Accepted Answer

Polypropylene glycol PPG-600 can be ordered directly through the Guoli Chemical sales team, with a minimum order quantity typically being 1 drum (50kg plastic drum). Specific pricing needs to be obtained by contacting sales for the latest quotation. Detailed Description Polypropylene glycol PPG-600 (CAS No.: 25322-69-4) is a regular industrial raw material product of Haian County Guoli Chemical Co., Ltd., stocked year-round. The product is now widely used in polyurethane synthesis, industrial defoamers, lubricant blending, metalworking fluids, daily chemicals, pharmaceuticals, and many other fields. According to the latest information from the Guoli Chemical database, prices are quoted in "RMB/ton", and the actual transaction price needs to be obtained by contacting the sales team for real-time quotations. Chemical raw material prices are subject to significant fluctuations due to upstream propylene oxide market conditions, supply volume, transportation distance, and other ctors, so fixed prices cannot be displayed on the website. Thank you for your understanding. Packaging Specifications and Ordering Information Packaging SpecificationDescription 50kg Plastic DrumStandard small packaging, suitable for sampling, small batch testing, or first trial. Usually the minimum order specification. 200kg Plastic DrumStandard industrial packaging, suitable for small to medium-scale production users for bulk procurement. IBC ToteBulk packaging, suitable for customers with large consumption such as polyurethane industry and lubricant blending plants, offering better cost efficiency. Ordering Process It is recommended to contact the Guoli Chemical sales team directly: You can obtain the sales hotline or leave an online message through the Guoli Chemical official website (www.guolichem.com). The sales engineer will provide one-on-one quotations and services based on your usage requirements, delivery address, and payment method. For first-time cooperation, Guoli Chemical usually supports applying for free samples for you to test and verify before placing a formal order, ensuring the product meets process requirements. Application Suggestions Before ordering, confirm that the product specification meets your application requirements: if used for polyurethane prepolymer synthesis, pay attention to hydroxyl value (178~197 mgKOH/g) and moisture (≤0.1%) indicators; if used for industrial defoamers or metalworking fluids, kinematic viscosity (100~130 mm²/s) is a key parameter; if used for cosmetics or pharmaceuticals, confirm the product grade and compliance documents with sales in advance. Precautions The product is hygroscopic. Unopened packaging has a shelf life of 12 months. After opening, use as soon as possible and keep the packaging sealed. Storage temperature is recommended to be maintained at 5°C~40°C. At low temperatures, product viscosity will increase or even solidify. Before use, warm to room temperature and stir to homogenize. Transportation is non-hazardous, and regular freight is sufficient. However, for long-distance transport, avoid sun exposure and freezing.

Question 4

Does polypropylene glycol PPG-600 meet environmental requirements? Can a test report be provided?

Accepted Answer

Polypropylene glycol PPG-600 is an environmentally friendly product with low toxicity, low aquatic toxicity, and low bioaccumulation potential, meeting conventional environmental requirements. For specific test reports, please contact Guoli Chemical. The following product technical parameters are provided for reference. Detailed Description According to Guoli Chemical's product safety technical data, polypropylene glycol PPG-600 (CAS No.: 25322-69-4) demonstrates good environmental performance: acute oral toxicity LD₅₀ > 2,000 mg/kg, classified as a low-toxicity substance; it exhibits low toxicity to aquatic organisms and has low bioaccumulation potential. The GHS classification assessment indicates that this product is not classified as a hazardous substance or mixture and does not require hazard classification under GHS standards. However, it should be noted that although the product itself has low environmental hazards, it is still necessary to strictly avoid direct discharge of large quantities of untreated product into water bodies or soil. Waste disposal should comply with local, provincial, and national regulations, and it is recommended to carry out incineration or recycling at qualified waste treatment cilities. Regarding test reports, Guoli Chemical's product database currently does not provide independent third-party test reports online. Official product test reports (such as ROHS, REACH, Halogen, Heavy Metals, etc. issued by third-party organizations like SGS or CTI) are usually issued with batch products or provided upon customer request. It is recommended that you directly contact Guoli Chemical's sales or technical service department, specifying the required test items (e.g., heavy metal content, hazardous substance limits, biodegradability, etc.), to obtain the corresponding batch's formal Certificate of Analysis (COA). The following are the complete technical parameters related to environmental protection and safety for polypropylene glycol PPG-600 recorded in Guoli Chemical's database, where heavy metal content, arsenic content, and other indicators can serve as important references for environmental compliance. Technical Parameters (Indicators Related to Environmental Compliance) Parameter NameTechnical IndicatorStandard/Method GHS Hazard ClassificationNot classified as hazardous substance or mixtureGHS Classification Criteria Acute Toxicity (Oral, Rat)LD₅₀ > 2,000 mg/kgOECD 401 Skin IrritationNon-irritatingOECD 404 Aquatic ToxicityLow aquatic toxicity— Bioaccumulation PotentialLow bioaccumulation potential— Heavy Metal Content (as Pb)≤ 10 mg/kgGuoli Chemical ctory Standard Arsenic Content (As)≤ 2 mg/kgGuoli Chemical ctory Standard Flash Point (Closed Cup)≥ 230 °CGB/T 261 FlammabilityNon-flammable liquid— Transport ClassificationNot classified as dangerous goods (according to UN Recommendations on the Transport of Dangerous Goods)UN RTDG Application Recommendations Development of Environmentally Friendly Formulations: PPG-600's low aquatic toxicity and low volatility make it suitable for developing environmentally friendly lubricants, metalworking fluids, and daily chemical products, potentially replacing traditional components with higher environmental risks. Wastewater Treatment Concerns: In industrial applications (such as defoamers, mold release agents), wastewater containing PPG-600 should be treated through conventional wastewater treatment processes before discharge to avoid high-concentration direct discharge. Although the product has low bioaccumulation potential, users are still advised to assess environmental exposure risks in end-use scenarios. Compliance Declaration Requirements: For REACH registration, TSCA compliance, or China's new chemical substance environmental management registration, you can use the above parameters combined with the formal test report provided by Guoli Chemical for declaration. Notes The heavy metal and arsenic content indicators provided in the database are ctory internal control standards. For actual test values of specific batches, please refer to the accompanying COA. If your application area involves special regulated industries such as food contact materials or medical devices, please be sure to declare the usage scenario to Guoli Chemical to obtain targeted compliance confirmation and relevant test reports. For waste disposal, it is recommended to incinerate at qualified waste treatment cilities. Do not directly discharge large quantities of untreated product into sewers, surce water, or groundwater.

Question 5

What are the advantages of polypropylene glycol PPG-600 compared to other similar products?

Accepted Answer

Polypropylene glycol PPG-600 has outstanding molecular weight and performance balance, with excellent compounding compatibility and high safety. It is the flagship product of Guoli Chemical in the field of nonionic polyether polyols. Detailed Description Compared with other polypropylene glycol series products on the market (such as PPG-200, PPG-400, PPG-1000, PPG-2000 and other molecular weight grades), Guoli Chemical's PPG-600 is in a "golden mid-molecular weight" range (molecular weight 570~630). Low molecular weight PPG (such as PPG-200/400) has low viscosity, relatively higher volatility and hygroscopicity, while ultra-high molecular weight PPG (such as PPG-2000 and above) has enhanced thickening and lubrication effects but reduced water solubility and ease of operation. PPG-600 achieves the optimal balance between the two - with moderate viscosity and good fluidity, it is convenient for pumping and metering operations while maintaining the flexibility imparting ability expected from polyether polyols. It is particularly suitable as a raw material for polyurethane prepolymer synthesis and as a multifunctional intermediate in various fields. From a formulation compatibility perspective, the nonionic nature of PPG-600 gives it excellent compounding flexibility, allowing it to coexist with anionic, cationic, and amphoteric surctants without charge interference. Although this is a general characteristic among similar products, its stability against acid, alkali, and hard water is particularly outstanding. It maintains functional stability over a wide pH range and in hard water environments, avoiding performance degradation that some similar products may experience under extreme conditions. Additionally, the low surce tension of PPG-600 provides excellent wetting, solubilizing, and dispersing capabilities, making it more efficient and requiring less dosage when used in defoamers, mold release agents, metalworking fluids, and other applications. In terms of safety, Guoli Chemical's PPG-600 has a flash point ≥230°C (closed cup), placing it in the high flash point tier among similar products, making it safer for operation under high-temperature process conditions. Its acute oral toxicity LD₅₀ > 2,000 mg/kg (low toxicity) and non-irritating to skin meet the strict safety requirements for raw materials in industries such as daily chemicals and pharmaceuticals. Overall, PPG-600 builds clear product advantages in three dimensions: molecular weight design, application adaptability, and safety compliance. Technical Parameters Parameter NamePPG-600 Typical ValueParameter Significance Molecular Weight (Mn)570~630Affects viscosity, flexibility, and reactivity Hydroxyl Value (mg KOH/g)178~197Reflects active hydrogen content, determines reactivity with isocyanates, etc. HLB Value1.5Hydrophilic-lipophilic balance value, suitable for W/O emulsification and wetting dispersion Kinematic Viscosity (cSt, 40℃)100~130Moderate viscosity, easy to handle, pump, and compound Cloud Point (℃, 1% aqueous solution)30~40Nonionic cloud point characteristic, suitable for temperature-responsive formulations pH (1% aqueous solution)5.0~7.0Near neutral, minimal impact on system pH Flash Point (℃, closed cup)≥230High flash point, excellent operational safety Density (g/cm³, 20℃)1.004~1.010Close to water, easy to disperse Active Content (%)≥99High purity, low impurities, stable performance Moisture Content (%)≤0.1Low moisture content, vorable for anhydrous reaction systems Application Recommendations Polyurethane Prepolymer/Elastomer Synthesis: Reacts as a polyether polyol with isocyanates to impart excellent flexibility and resilience to the finished product, recommended for elastomeric products requiring high dynamic performance. Industrial Defoamers: Utilizes low surce tension and low foaming characteristics, suitable for industrial systems prone to foaming such as fermentation, papermaking, and coatings. Recommended addition amount is 0.1%~1.0% of the total formulation. Synthetic Lubricants and Metalworking Fluids: Acts as a base oil or thickening component, providing good lubricity, thermal oxidation stability, and cooling effects. Suitable for water-glycol fire-resistant hydraulic fluids and cutting fluid formulations. Daily Chemicals and Pharmaceuticals: Used as a cosmetic solvent, humectant, and pharmaceutical ointment base. Gentle on the skin, good biocompatibility, meeting daily chemical grade safety requirements. Nonionic Surctant Intermediates: After etherification or esterification modification, can be used to prepare high-performance emulsifiers and dispersants for detergent and industrial auxiliary compounding. Notes PPG-600 may experience increased viscosity or solidification at low temperatures ( During operation, direct contact with strong oxidizers (such as peroxides, nitric acid, etc.) and strong acids should be avoided to prevent violent reactions. The product is slightly hygroscopic. After opening the package, it is recommended to use it as soon as possible and keep the container sealed to prevent moisture absorption from affecting purity. Eye contact may cause mild discomfort; chemical safety goggles are recommended. Good ventilation should be maintained in high-temperature processes. Recommended storage temperature is 5~40°C, away from heat sources and open flames. Use containers made of stainless steel, carbon steel, or polypropylene for storage.

Question 6

How to store polypropylene glycol PPG-600? How long is the shelf life?

Accepted Answer

Polypropylene glycol PPG-600 should be stored in a cool, dry, and well-ventilated environment at 5°C to 40°C, with the container sealed tightly; under recommended conditions, unopened original packaging can usually be stably stored for 2 years, but the product database currently does not list official shelf life data. Detailed Explanation Polypropylene glycol PPG-600 is a chemically stable non-ionic polyether polyol that does not decompose under normal temperature and pressure. The key points for its storage are: prevent moisture absorption, avoid high temperatures, and keep away from strong oxidants. The product has some hygroscopicity and will slowly absorb moisture when exposed to air, so keeping the packaging container sealed is crucial for maintaining long-term product quality stability. In low-temperature environments (below 5°C), the product's viscosity will significantly increase or even solidify, but this is a physical change that does not affect chemical properties. Before use, simply warm the product to room temperature and stir evenly to restore its normal state. Regarding shelf life, the Guanli Chemical product database currently does not include official shelf life data for this product. Based on industry practices and common experience with similar polyether products, under strict adherence to recommended storage conditions and with the container unopened, polypropylene glycol PPG-600 can usually maintain stable technical indicators for 24 months from the date of manucture. If the product has been opened and used, it is recommended to use it within 6 months and immediately reseal the container after each use. During storage, if significant changes in product appearance are observed (such as severe turbidity, stratification, discoloration, or odor), or if there is any doubt about the product's condition before use, it is recommended to contact Guanli Chemical's technical service team for quality re-inspection and confirmation. Do not use the product directly. Technical Parameters (Storage Related) Parameter CategoryIndex/Requirement Chemical StabilityStable under normal temperature and pressure, avoid strong oxidants Recommended Storage Temperature5°C to 40°C AppearanceColorless to light yellow viscous liquid HygroscopicityHygroscopic Flash Point≥ 230°C (Closed Cup) Recommended Packaging MaterialsStainless steel, carbon steel, polypropylene containers Shelf LifeNo official data (Industry suggestion: 2 years unopened) Storage Key Recommendations Seal and prevent moisture: The product is hygroscopic; after opening, immediately tighten the lid and consider adding a moisture-proof liner at the container opening. Temperature control: Avoid storing outdoors, in high-temperature workshops, or near heat sources such as steam pipes and boilers; in low-temperature winter areas, pay attention to freeze protection; if solidified, thaw by warming and stir evenly before use. Separate storage: Store in dedicated warehouses or areas, strictly separated from strong oxidants (e.g., peroxides, concentrated nitric acid) and strong acids; storage areas should be equipped with anti-leakage trays or containment dikes. First-in, first-out: It is recommended to implement the "first-in, first-out" inventory management principle to avoid long-term accumulation. Notes Although this product is not a hazardous chemical, it must not be stored together with food, beverages, or feed items in the same warehouse. If the product needs to be reused after long-term storage beyond the suggested period, it is recommended to sample and test key indicators such as hydroxyl value, moisture content, acid value, and viscosity; confirm they are qualified before use. Disposal of waste should comply with local environmental regulations; it is recommended to treat in licensed incineration cilities and not discharge directly into water bodies or soil.

Question 7

What safety precautions should be taken when using polypropylene glycol PPG-600?

Accepted Answer

Polypropylene glycol PPG-600 is a non-hazardous substance and is safe under normal use conditions, but basic chemical handling procedures should still be followed, with special attention to eye protection, high-temperature fire prevention, and leak management. Detailed Description Polypropylene glycol PPG-600 is a non-ionic polymer with high safety. According to GHS standards, it is not classified as a hazardous substance or mixture. Its acute oral toxicity is low (rat LD₅₀ > 2,000 mg/kg), making it a low-toxicity substance; it is non-irritating to the skin, has a flash point above 200°C (closed cup), is not flammable at normal operating temperatures, and is not classified as dangerous goods for transportation. These characteristics make PPG-600 relatively safe in industrial applications, but this does not mean that safety operating procedures can be completely ignored. In actual use, three main aspects require attention: first, eye contact may cause mild discomfort (such as redness and tearing), and it is recommended to wear chemical safety goggles to prevent splashes; second, prolonged or repeated skin contact may cause skin detting, so it is recommended to wear nitrile or neoprene protective gloves and wash hands carefully after operation; third, although the flash point is high, the product can still burn at high temperatures and release toxic fumes such as carbon monoxide, aldehydes, and ketones. Therefore, ensure good ventilation and keep away from open flames during heating processes. For storage, PPG-600 should be kept in a cool, dry, and well-ventilated environment, with a recommended storage temperature of 5°C to 40°C. Special attention should be paid to the ct that low temperatures may cause the product to thicken or even solidify; before use, it should be warmed to room temperature and stirred evenly. It should also be kept away from strong oxidizing agents (such as peroxides, perchlorates, nitric acid) and strong acids to prevent violent reactions. Recommended packaging containers include stainless steel, carbon steel, or polypropylene, and they should be sealed to prevent moisture absorption and contamination. Key Safety Parameters Safety IndicatorParameter ValueDescription GHS Hazard ClassificationNon-hazardous substanceNo classification required per GHS standards Acute Oral Toxicity (Rat)LD₅₀ > 2,000 mg/kgLow toxicity substance Skin IrritationNon-irritatingProlonged contact may cause detting Eye IrritationMild discomfortPossible redness and tearing Flash Point (Closed Cup)> 200°CNot flammable under normal operating temperatures Recommended Storage Temperature5°C to 40°CLow temperatures may cause solidification Transport ClassificationNon-dangerous goodsPer UN transport recommendations Operating and Emergency Response Recommendations Personal Protective Equipment Requirements Respiratory Protection: No special protection is generally required; if oil mist or vapor concentrations are high and ventilation is insufficient, wear an organic vapor filter respirator. Hand Protection: It is recommended to wear nitrile or neoprene protective gloves and replace them promptly if contaminated. Eye Protection: It is recommended to wear chemical safety goggles to prevent splashes from entering the eyes. Body Protection: Wear conventional work protective clothing; heavily contaminated clothing should be washed before reuse. Ventilation Conditions: Maintain good ventilation in the workplace; install local exhaust ventilation during heating or spraying processes. Leak Emergency Procedures Small Leak: Absorb with inert materials such as sand, earth, or vermiculite, collect and place in a sealed container for disposal as chemical waste. Large Leak: Build dikes or dig pits to contain the spill, use explosion-proof pumps to transfer to dedicated containers for recovery or disposal. Prevent the leak from entering sewers, surce water, or groundwater; if contamination has occurred, immediately notify the local environmental authority. First Aid Measures Skin Contact: Remove contaminated clothing and rinse with copious amounts of soap and water for at least 15 minutes; seek medical attention if irritation persists. Eye Contact: Hold eyelids open and rinse thoroughly with plenty of flowing water or saline for at least 15 minutes; seek medical attention if discomfort persists. Ingestion: Do not induce vomiting to avoid aspiration into the lungs; rinse mouth with water and seek immediate medical attention. Inhalation: Move the affected person to fresh air; if breathing is difficult, perform artificial respiration and seek medical attention. Precautions Although PPG-600 is not classified as dangerous goods and is generally safe, explosion-proof equipment should still be used and preventive measures maintained during high-temperature processes. The product may produce toxic fumes when burning; firefighters should wear self-contained positive-pressure breathing apparatus and full protective gear, and use carbon dioxide, dry powder, foam, or water mist for extinguishing; do not use straight water streams. Waste disposal should follow local regulations; incineration or recycling at qualified waste treatment cilities is recommended. Do not discharge directly into waterways or soil.

Question 8

How to use polypropylene glycol PPG-600? What is the recommended dosage?

Accepted Answer

The usage method of polypropylene glycol PPG-600 varies depending on the application field. Currently, there is no unified fixed addition amount data in the product database. It is recommended to determine the optimal dosage through experiments based on the specific process. The following are industry-general recommended addition ranges and usage methods according to application fields. Detailed Description 1. Polyurethane Industry Application As a core component of polyether polyol, PPG-600 directly participates in the polymerization reaction with isocyanates (such as MDI, TDI) according to the formula ratio to synthesize polyurethane prepolymers and elastomers. Before use, the product should be preheated to room temperature (viscosity increase or solidification may occur after low-temperature storage), stirred evenly, and then added by measuring according to the prepolymer formula. It is recommended to operate under nitrogen protection or in a dry environment to avoid moisture interfering with the isocyanate reaction. The recommended addition amount is usually 20% to 60% of the total prepolymer formula (adjusted based on target hardness and flexibility). 2. Industrial Defoamer Utilizing the low surce tension (approximately 33 mN/m) and good dispersibility of PPG-600, it can be used as a base component or active ingredient of industrial defoamers. When in use, it is directly added to the medium requiring defoaming, or pre-compounded with dispersants and emulsifiers to form a defoamer emulsion before addition. It is suitable for systems such as fermentation, papermaking, and coatings. The recommended addition amount is 0.01% to 0.5% of the total system amount, which needs to be optimized through experiments based on the extent of foam and process conditions. 3. Release Agent As an active component of the release agent, PPG-600 can be mixed with solvents (such as water or organic solvents) and emulsifiers in proportion to prepare a release solution, which is then sprayed or brushed onto the mold surce to form a uniform isolation film. The recommended mass proportion of PPG-600 in the formulation is 5% to 30% (in the final release solution), and the specific concentration depends on the mold material and release difficulty. 4. Lubricating Oil and Metalworking Fluids When used as synthetic lubricating base oil or additive, it is directly added to the base oil according to the formula ratio and stirred evenly. In water-glycol fire-resistant hydraulic fluids, it serves as a thickening and lubricating component, usually used in combination with other functional additives. The recommended addition amount in metalworking fluids (cutting fluids, quenchants) is 5% to 20% of the total concentrate amount, significantly enhancing lubrication and cooling performance. 5. Daily Chemical and Pharmaceutical Applications In cosmetics, as a humectant or solvent, the recommended dosage is 1% to 10% of the total formula amount. It can be added to the water phase or oil phase and stirred evenly. In pharmaceutical ointment/suppository bases, it is usually used as one of the main components of water-soluble bases, with the amount determined according to the specific formulation. When used as an intermediate for nonionic surctants, further chemical modification through etherification or esterification reactions is required, and PPG-600 is charged as a reaction starting material according to the stoichiometric ratio. Technical Parameters Parameter ItemSpecification Indicator AppearanceColorless to light yellow viscous liquid Molecular Weight570~630 Hydroxyl Value (mg KOH/g)178~197 HLB ValueApproximately 1.5 (strong lipophilicity) pH (1% Aqueous Solution)5.0~7.0 Density (25℃, g/cm³)1.004~1.010 Kinematic Viscosity (40℃, mm²/s)100~130 Cloud Point (℃)30~40 Flash Point (℃, Closed Cup)≥230 Moisture (%)≤0.1 Acid Value (mg KOH/g)≤0.1 SolubilitySoluble in water, easily soluble in alcohols, esters, and ketone organic solvents Application Suggestions Pre-treatment before use: It is normal for the product to have increased viscosity or solidify after low-temperature storage. Before use, warm the product to 15℃~35℃ and stir thoroughly until fluidity is restored, then sample and measure. Compounding order: In emulsification or dispersion systems, it is recommended to first mix PPG-600 thoroughly with the oil phase components, then slowly add the water phase, which helps to obtain a more stable emulsion system. Dosage optimization: The recommended addition ranges for the above fields are industry empirical values. The actual optimal dosage needs to be determined through gradient experiments based on the specific formulation system. Storage conditions: Recommended storage temperature is 5℃~40℃, stored in a cool, dry, and ventilated place. Keep the container sealed to prevent moisture absorption, and keep away from strong oxidizers and strong acids. Packaging specifications: Guoli Chemical offers three packaging options: 50kg plastic drum, 200kg plastic drum, and IBC tote, allowing flexible selection for users of different scales. Precautions PPG-600 is a lipophilic nonionic polymer (HLB value approximately 1.5). When used in aqueous systems, it usually needs to be combined with emulsifiers or solubilizers to achieve good dispersion. It is recommended to wear protective gloves and chemical safety goggles during operation to avoid prolonged skin contact and eye splashes. The product is highly hygroscopic. After opening, use it as soon as possible and seal it promptly to prevent moisture absorption from the environment affecting product quality. When operating at high temperatures (such as polyurethane synthesis), ensure good ventilation and keep away from open flames. Although the flash point is high (≥230℃), there is still a risk of combustion at high temperatures. Disposal of waste should comply with local environmental regulations. It is recommended to hand it over to a qualified waste disposal agency for incineration or recycling, and do not discharge directly into water bodies or soil.

Question 9

What are the main industries and processes where polypropylene glycol PPG-600 is primarily used?

Accepted Answer

Polypropylene glycol PPG-600 is widely used in four major fields: polyurethane synthesis, industrial auxiliaries, lubricants and metalworking fluids, as well as daily chemicals and pharmaceuticals, serving as a versatile non-ionic polymer intermediate. Detailed Description Polypropylene glycol PPG-600 (CAS: 25322-69-4) is a non-ionic propylene oxide polymer, appearing as a colorless to slightly yellow transparent viscous liquid. With its excellent emulsifying and dispersing properties, stability against acids, alkalis, and hard water, low volatility, and non-ionic characteristics, PPG-600 plays an irreplaceable functional role in multiple industries. Its core value lies in its ability to act both as a synthetic raw material in polymerization reactions and as a functional additive for direct use, offering high flexibility. From the perspective of process adaptability, PPG-600's high flash point (>200°C closed cup) enables it to withstand high-temperature process conditions, while its broad compatibility with anionic, cationic, and amphoteric surctants provides formulators with significant compounding freedom. In polyurethane prepolymer synthesis, PPG-600, as a core polyether polyol component, reacts with isocyanates, significantly enhancing the flexibility, resilience, and hydrolysis resistance of the final product. In the field of industrial auxiliaries, PPG-600's low surce tension and good dispersibility make it an efficient active component in defoamers and mold release agents; in metalworking fluids, it serves a dual function of lubrication and cooling. Additionally, its mild skin compatibility and good biocompatibility make it important in cosmetic moisturizers and pharmaceutical preparation matrices. Detailed Application Fields and Processes Application FieldSpecific Process/UseFunction of PPG-600 Polyurethane IndustryPolyurethane prepolymer and elastomer synthesisAs a core polyether polyol component, reacts with isocyanates to endow the product with flexibility, resilience, and hydrolysis resistance Polyurethane foam plasticsProvides chain segment flexibility and reactivity adjustment Industrial AuxiliariesIndustrial defoamers (fermentation, papermaking, coatings)Utilizes low surce tension and dispersibility to quickly break foam and inhibit its regeneration Active component in mold release agentsForms an effective release film, reducing adhesion for smooth demolding Plasticizers and softenersCompatible with resin systems, increasing flexibility and soft feel of plastics, rubber, and textiles Intermediates for non-ionic surctant synthesisPreparation of detergents, emulsifiers, etc., through etherification or esterification reactions Lubricants and Metalworking FluidsComponents of synthetic lubricant base oils and hydraulic fluidsProvides lubricity, thermal oxidation stability, and high viscosity index Water-glycol fire-resistant hydraulic fluidsAs a thickener and lubricating component, enhances viscosity stability and load-bearing capacity Metalworking fluids (cutting fluids, quenching fluids)Provides lubrication and cooling effects, reducing tool wear; regulates cooling rate in quenching fluids Daily Chemicals and PharmaceuticalsCosmetic solvents and moisturizersMild and skin-friendly, providing moisturizing properties and feel improvement Pharmaceutical ointment and suppository basesAs a water-soluble base, offers good biocompatibility and drug release properties Detergents and personal care productsEnhances formulation uniformity and user experience Textile IndustryTextile softening finishingAs a softener component, improves bric hand feel Textile auxiliariesWetting agent function, improving efficiency in dyeing and finishing processes Application Recommendations Polyurethane Synthesis Process: It is recommended to use PPG-600 as the soft segment component, compounded with other polyether polyols of different molecular weights based on the hardness and elasticity requirements of the target product. During prepolymer synthesis, strictly control moisture content (recommended below 0.05%) to avoid side reactions with isocyanates. Defoamer Formulation: PPG-600 can serve as a base component in defoamers, used synergistically with hydrophobic silica, silicones, etc. The recommended dosage range is 0.1% to 2% depending on the foam level of the specific system. Metalworking Fluid Formulation: In water-based cutting fluids and quenching fluids, the recommended addition amount of PPG-600 is 5% to 30%, depending on the required lubricity and cooling capacity. It can be compounded with rust inhibitors, extreme pressure additives, etc. Daily Chemical Products: When used as a moisturizer or solvent in cosmetic formulations, the recommended addition amount is 1% to 10%. Its non-ionic nature ensures good compatibility with various surctant systems. Precautions Storage Conditions: Store in a cool, dry place at 5°C to 40°C. Low temperatures may increase viscosity or cause solidification; warm to room temperature and stir evenly before use. Safe Operation: Flash point >200°C (closed cup), not flammable under normal operating temperatures, but it is still recommended to use explosion-proof equipment and maintain good ventilation in high-temperature processes. Wear chemical safety goggles and nitrile rubber gloves during operation. Incompatible Materials: Keep away from strong oxidizing agents (e.g., peroxides, perchlorates, nitric acid) and strong acids to avoid violent reactions. Environmental Protection: Low aquatic toxicity, but avoid direct discharge into water bodies. Disposal must comply with local regulations; incineration in licensed cilities or recycling is recommended. First Aid: In case of eye contact, immediately flush with plenty of running water for at least 15 minutes; for skin contact, wash thoroughly with soap and water; if ingested, do not induce vomiting and seek medical attention immediately.

Question 10

What are the physicochemical technical parameters of polypropylene glycol PPG-600?

Accepted Answer

Comprehensive Overview of Physicochemical Parameters of Polypropylene Glycol PPG-600 — A Nonionic Polyether Polyol with Hydroxyl Value 178~197 mgKOH/g and Viscosity 100~130 mPa·s Detailed Description Polypropylene glycol PPG-600 (CAS No.: 25322-69-4) is a nonionic propylene oxide polymer produced by Haian Guoli Chemical Co., Ltd., with the molecular formula HO(C3H6O)nH (n≈10), a molecular weight between 570~630, and an appearance of a colorless to light yellow transparent viscous liquid. This product exhibits excellent chemical stability, maintaining stability under normal temperature and pressure, and has good compatibility with anionic, cationic, and amphoteric surctants, offering high formulation flexibility. As a nonionic surctant with a low HLB value (approximately 1.5), PPG-600 features low foaming properties, is soluble in water, and readily soluble in organic solvents such as alcohols, esters, and ketones, with a surce tension of about 33 mN/m. The product has a high flash point (≥230°C), a melting point below -20°C, maintains stable performance under a wide pH range and hard water conditions, exhibits excellent resistance to acids, alkalis, and hard water, and possesses good hygroscopicity as well as lubricating and moisturizing properties. The following technical parameter data are sourced from Guoli Chemical's product database, covering comprehensive information from physical properties and chemical indicators to packaging specifications, providing accurate reference for product selection, formulation design, and quality testing. Technical Parameters Parameter ItemTechnical Indicator Product NamePolypropylene Glycol PPG-600 CAS Number25322-69-4 Molecular FormulaHO(C₃H₆O)nH, n≈10 Molecular Weight570~630 AppearanceColorless to light yellow transparent viscous liquid Ionic TypeNonionic Active Content≥99% Moisture Content≤0.1% Density (25°C)1.004~1.010 g/cm³ Kinematic Viscosity (40°C)100~130 mPa·s Low Shear Viscosity (25°C)150~200 mPa·s Refractive Index (25°C)1.449~1.452 Melting Point< -20°C Flash Point (Closed Cup)≥230°C Cloud Point30~40°C HLB ValueApprox. 1.5 Hydroxyl Value178~197 mgKOH/g Acid Value≤0.1 mgKOH/g Saponification Value≤1 mgKOH/g Amine Value≤0.1 mgKOH/g Iodine Value≤1 gI₂/100g Unsaturation≤0.01 mmol/g pH Value (1% Aqueous Solution)5.0~7.0 pH Value (5% Aqueous Solution)5.0~8.0 Surce TensionApprox. 33 mN/m Foaming CharacteristicLow foaming HygroscopicityHygroscopic SolubilitySoluble in water, readily soluble in organic solvents such as alcohols, esters, and ketones Alkali ResistanceStable Chemical StabilityStable under normal temperature and pressure, avoid strong oxidizers Heavy Metal Content≤10 ppm Arsenic Content≤2 ppm Packaging Specifications50kg plastic drum / 200kg plastic drum / IBC tote Application Recommendations Based on the above technical parameters, the core application directions of polypropylene glycol PPG-600 can be summarized as follows: The hydroxyl value of 178~197 mgKOH/g makes it highly suitable as a polyether polyol component for polyurethane prepolymers and elastomer synthesis, reacting with isocyanates to impart excellent flexibility and resilience to the final products. The viscosity of 100~130 mPa·s and low foaming characteristic make it an ideal base component for industrial defoamers (fermentation, papermaking, coatings). In the fields of synthetic lubricants and metalworking fluids, its high flash point (≥230°C) and excellent lubricity ensure operational safety under high-temperature conditions. In daily chemicals and pharmaceuticals, its low toxicity (LD₅₀ > 2,000 mg/kg) and good skin-friendly moisturizing properties make it suitable for cosmetic solvents and pharmaceutical ointment bases. Precautions Storage Temperature: Recommended storage in a cool, dry environment between 5°C and 40°C. Low temperatures may increase viscosity or even cause solidification; naturally warm to room temperature and stir evenly before use. Incompatible Materials: Keep away from strong oxidizers (e.g., peroxides, perchlorates, nitrates) and strong acids to prevent violent reactions. Moisture Protection: The product is hygroscopic; ensure the container is sealed after use to avoid prolonged exposure to humid air, which may increase moisture content. Operational Protection: Although skin irritation is low, it is recommended to wear chemical safety goggles and chemical-resistant gloves during handling to avoid prolonged or repeated contact that may cause skin detting. Packaging Selection: Storage and transport containers made of stainless steel, carbon steel, or polypropylene are recommended.

Polypropylene Glycol PPG-600

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Product Overview

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Property	Value
CAS No.	25322-69-4
Molecular Formula	HO(C3H6O)nH, n≈10
Appearance	Colorless to pale yellow viscous liquid
Ionic Type	Nonionic
Avg. Molecular Weight	570~630
Cloud Point	30~40
Active Content	≥99
pH Value(1%)	5.0~7.0
pH Value(5%)	5.0~8.0
Iodine Value	≤1
Solubility	Soluble in water; readily soluble in alcohols, esters and ketones
Surface Tension	~33
Acid Value	≤0.1
Saponification Value	≤1
Hydroxyl Value	178~197
Moisture	≤0.1
Density	1.004~1.010
Kinematic Viscosity	100~130
Refractive Index	1.449~1.452
Flash Point	≥230
Hygroscopicity	Hygroscopic
Chemical Stability	Stable at room temperature; avoid strong oxidizers
Amine Value	≤0.1
Foam Property	Low foam
Alkali Resistance	Stable
Unsaturation	≤0.01
Viscosity	100~130
Melting Point	< -20
Low Shear Viscosity	150~200
Solid Content	≥99
Free Alcohol	≤0.1
Heavy Metal	≤10
Arsenic	≤2

Polypropylene Glycol PPG-600

Product Details

Applications

Properties

Safety

Product Overview

Performance Features

Application Guidelines

Packaging and Storage

PPG Applications

Product Properties

Safety

GHS

Handling

Storage

First Aid

Related Products

Polypropylene Glycol PPG-400

Polypropylene Glycol PPG-200