Question

What are the precautions for using polypropylene glycol PPG-600?

Answer
2026-05-17 官方文档 聚丙二醇PPG-600

Polypropylene glycol PPG-600 is a low-toxicity, non-hazardous substance, but care should still be taken during use regarding eye protection, ventilation, proper storage, and emergency response to ensure safe and efficient use.

Detailed Description

Polypropylene glycol PPG-600 is a nonionic propylene oxide polymer, appearing as a colorless to slightly yellow transparent viscous liquid with a flash point >200°C (closed cup). It is not flammable at normal operating temperatures. Its acute oral toxicity LD₅₀ > 2,000 mg\/kg, indicating low toxicity, and it is non-irritating to the skin. These characteristics make it relatively safe to handle overall, but standard chemical operating procedures should still be followed.

During use, special attention should be paid to preventing eye contact, as this product may cause mild discomfort (such as redness or tearing). It is recommended to wear chemical safety goggles during operation, and nitrile rubber or neoprene protective gloves for hand protection. Although the flash point is high, in high-temperature processes (such as heating, spraying, or operations generating aerosols), ensure good ventilation in the work area and install local exhaust ventilation, while keeping away from open flames.

The product has good compatibility with anionic, cationic, and amphoteric surfactants, offering high formulation flexibility. In low-temperature environments, the product's viscosity may increase or even solidify; warm it to room temperature and stir evenly before use, avoiding local overheating. After operation, wash hands thoroughly; eating, drinking, and smoking are prohibited in the work area.

Technical Parameters

ItemParameter
AppearanceColorless to slightly yellow transparent viscous liquid
Flash point (closed cup)> 200 ℃
Acute toxicity (oral, rat)LD₅₀ > 2,000 mg\/kg (low toxicity)
Skin irritationNon-irritating
Eye contactMay cause mild discomfort
GHS classificationNot classified as hazardous substance
Transport classificationNot classified as dangerous goods
Recommended storage temperature5 ℃ to 40 ℃

Application Recommendations

In practical applications, the following points should be noted based on specific scenarios:

  • Polyurethane synthesis: When used as a polyether polyol component reacting with isocyanates, strictly control the moisture content, keep the container sealed to prevent moisture absorption, to avoid affecting the quality of the prepolymer.
  • Defoamer formulation: Utilizing its low surface tension property, it is recommended to pre-mix thoroughly with other antifoam components to ensure uniform dispersion for optimal defoaming and foam suppression.
  • Lubricants\/Metalworking fluids: Pay attention to compatibility with other additives; in quench oil applications, precisely control the addition ratio according to process requirements to regulate the cooling rate.
  • Cosmetics and pharmaceutical applications: In cosmetics, pay attention to the amount added to optimize skin feel; for pharmaceutical ointments and suppository bases, ensure the product meets corresponding pharmaceutical excipient standards.

Precautions

  • Incompatible materials: Keep away from strong oxidizers (such as peroxides, perchlorates, nitric acid) and strong acids to avoid vigorous reactions.
  • Storage requirements: Store in a cool, dry, well-ventilated dedicated warehouse; recommended containers made of stainless steel, carbon steel, or polypropylene; keep sealed to prevent moisture absorption and contamination; keep away from fire, heat sources, and direct sunlight.
  • Eye contact emergency: Immediately flush with plenty of running water or saline solution, holding eyelids open, for at least 15 minutes; if discomfort persists, seek medical attention immediately.
  • Skin contact emergency: Remove contaminated clothing; wash skin thoroughly with plenty of soap and water for at least 15 minutes.
  • Spill handling: Contain and absorb with inert absorbent materials such as sand, earth, or vermiculite; prevent entry into drains or surface waters.
  • Fire emergency: Use carbon dioxide, dry powder, foam, or water spray; never use a direct water stream. Combustion may produce toxic fumes including carbon monoxide, aldehydes, and ketones; firefighters must wear self-contained positive-pressure breathing apparatus.
  • Ingestion handling: Do not induce vomiting to prevent aspiration into the lungs; rinse mouth thoroughly with water and seek medical attention immediately.
  • Disposal: Incinerate or recycle at approved waste treatment facilities; do not discharge directly into waterways or soil.